Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Hajo Jongepier"'
1
Skin-blanching is associated with FEV1, allergy, age and gender in asthma families
Autor: Maarten van den Berge, Eef D. Telenga, Judith M. Vonk, Dirkje S. Postma, Gerard H. Koppelman, Hajo Jongepier, Leslie A. Lange
Publikováno v: Respiratory Medicine, 106(10), 1376-1382. W B SAUNDERS CO LTD
Background: Inhaled glucocorticosteroids reduce airway inflammation in asthma patients, thereby improving lung function and reducing airway hyperresponsiveness and symptoms. The response to glucocorticosteroids can be measured with the glucocorticost
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7032c27afe1ddad96f4ccd6c145823
https://research.rug.nl/en/publications/ed0fd857-d28f-4c1a-a8d6-3400baf886d0
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2
Lung function decline in asthma
Autor: Arie Dijkstra, Hajo Jongepier, ten Nicolaas Hacken, Gerard H. Koppelman, Dirkje S. Postma, Judith M. Vonk, Wim Timens, Jan P. Schouten
Publikováno v: Thorax, 61(2), 105-110. BMJ PUBLISHING GROUP
Inhaled corticosteroids (ICS) provide short term benefits in asthma but the long term effects are still unknown.281 patients diagnosed with moderate to severe asthma in 1963-75 were re-examined in 1991-9. Information was collected on forced expirator
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb03e57263e8d01ffbc4edc432b87d6b
https://doi.org/10.1136/thx.2004.039271
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3
Differential desensitization of homozygous haplotypes of the beta(2)-adrenergic receptor in lymphocytes
Autor: Haukeline H. Volders, Jaap Oostendorp, Eugene R. Bleecker, Henk F. Kauffman, S. Adriaan Nelemans, Hajo Jongepier, Dirkje S. Postma, Johan Zaagsma, Deborah A. Meyers, Herman Meurs, H. Marike Boezen
Publikováno v: American Journal of Respiratory and Critical Care Medicine, 172(3), 322-328. AMER THORACIC SOC
Single-nucleotide polymorphisms of the beta(2)-adrenergic receptor gene and its 5 ' promoter have been associated with differences in receptor function and desensitization. Linkage disequilibrium may account for inconsistencies in reported effects of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db5e72ebda3d4e6aba4a0f9dc21bd47
https://doi.org/10.1164/rccm.200409-1162oc
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4
Genome screen for asthma and bronchial hyperresponsiveness
Autor: Timothy D. Howard, Elizabeth J. Ampleford, Deborah A. Meyers, O. Colin Stine, Dirkje S. Postma, Eugene R. Bleecker, Gerard H. Koppelman, Hajo Jongepier
Publikováno v: Journal of Allergy and Clinical Immunology, 115(6), 1169-1175. MOSBY-ELSEVIER
Background: Asthma is a common respiratory disease caused by the interaction of genetic susceptibility and exposure to various environmental factors. Passive smoke exposure, characterized by parental smoking, has been shown to be a risk factor for th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc3aefb7fa0fa376e22f65c190f946a
https://doi.org/10.1016/j.jaci.2005.01.070
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5
Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel
Autor: Dirkje S. Postma, Timothy D. Howard, Eugene R. Bleecker, Gregory A. Hawkins, Gerard H. Koppelman, Hajo Jongepier, Deborah A. Meyers, Richard S. Smith, PJ Amelung
Publikováno v: DNA sequence, 15(3), 167-173
The glucocorticoid receptor (GR) gene (NR3C1) maps to 5q31, a region genetically linked to asthma. In this study, NR3C1 exons 1A, 1B, and exons 1C to 9 (alpha and beta) were sequenced in a screening panel of asthmatics and unaffected controls from US
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95211f918c10b3abeeaef8b30b037158
https://doi.org/10.1080/10425170410001704517
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6
Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma
Autor: Hendrika Boezen, Arie Dijkstra, Eugene R. Bleecker, SL Zheng, Hajo Jongepier, Timothy D. Howard, J. M. Vonk, Dirkje S. Postma, Deborah A. Meyers, Gerard H. Koppelman
Publikováno v: Clinical and Experimental Allergy, 34(5), 757-760. Wiley
BACKGROUND: Asthma is a genetically complex disease characterized by respiratory symptoms, intermittent airway obstruction and airway hyper-responsiveness due to airway inflammation and remodelling. The ADAM33 gene is associated with asthma and airwa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db02c9d304bea7439bf4308e77fcdb4f
https://doi.org/10.1111/j.1365-2222.2004.1938.x
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7
Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations
Autor: Gerard H. Koppelman, Eugene R. Bleecker, Jianfeng Xu, Deborah A. Meyers, Dirkje S. Postma, Wendy C. Moore, Timothy D. Howard, Siqun L. Zheng, Hajo Jongepier
Publikováno v: Journal of Allergy and Clinical Immunology. 112:717-722
Background Asthma is a complex genetic disease characterized by reversible intermittent airway obstruction and respiratory symptoms primarily caused by acute and chronic bronchial inflammation. Recently, a gene potentially involved in airway remodeli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb9c3e02901ad3defa06e751130aa39
https://doi.org/10.1016/s0091-6749(03)01939-0
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9
Genomewide screen for pulmonary function in 200 families ascertained for asthma
Autor: Deborah A. Meyers, Gerard H. Koppelman, Dirkje S. Postma, Timothy D. Howard, Hajo Jongepier, Eugene R. Bleecker
Publikováno v: American Journal of Respiratory and Critical Care Medicine, 172(4), 446-452. AMER THORACIC SOC
Changes in pulmonary function are important in determining asthma outcome. Genetic factors may influence airway obstruction in asthma. We performed a genomewide screen in 200 families of probands objectively diagnosed with asthma in the 1960s to iden
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21c3d95234bf53c72f8ab757a5ad593
https://research.rug.nl/en/publications/88cfaf8a-ac08-44a2-83f5-8ef7caef131c
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10
Polymorphisms in SPINK5 are not associated with asthma in a Dutch population
Autor: Marcel Bruinenberg, Ilja M. Nolte, Gerard J. te Meerman, Hajo Jongepier, Dirkje S. Postma, Eugene R. Bleecker, Gerard H. Koppelman, Deborah A. Meyers
Publikováno v: Journal of Allergy and Clinical Immunology, 115(3), 486-492. MOSBY-ELSEVIER
Background: Asthma and allergic phenotypes are complex genetic diseases with known linkage to chromosome 5q. This region has many candidate genes, including serine protease inhibitor Kazal type 5 (SPINK5), which has been associated with asthma and at
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eda7568f1c379684a3b44e26455dddb
https://pubmed.ncbi.nlm.nih.gov/15753894
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