Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hajo, Kries"'
Autor:
Annika Bande, Eva Blasco, Georg Dierkes, Johanna Heine, Alexander Hinz, Constantin Hoch, Ullrich Jahn, Hajo Kries, Björn Meermann, Erik Strub, Frank Tambornino, Carl Christoph Tzschucke
Publikováno v:
Nachrichten aus der Chemie. 71:52-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45be51ce7e9e81e33071a8300da5d5a4
https://doi.org/10.1002/nadc.20234133000
https://doi.org/10.1002/nadc.20234133000
Autor:
Annika Bande, Guillaume Delaittre, Georg Dierkes, Johanna Heine, Alexander Hinz, Constantin Hoch, Ullrich Jahn, Hajo Kries, Björn Meermann, Carl Christoph Tzschucke, Markus Zegke
Publikováno v:
Nachrichten aus der Chemie. 70:52-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369068319566b6ba67e53ebe1ed1e171
https://doi.org/10.1002/nadc.20224132391
https://doi.org/10.1002/nadc.20224132391
Autor:
Philipp Stephan, Chloe Langley, Daniela Winkler, Jérôme Basquin, Lorenzo Caputi, Sarah E. O’Connor, Hajo Kries
Publikováno v:
Angewandte Chemie International Edition
Engineering of biosynthetic enzymes is increasingly employed to synthesize structural analogues of antibiotics. Of special interest are non-ribosomal peptide synthetases (NRPSs) responsible for production of important antimicrobial peptides. Here, di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81461b0437bd3d712d12dd31e8320c1
https://hdl.handle.net/21.11116/0000-000D-4CA3-621.11116/0000-000D-4CA5-421.11116/0000-000D-4CA6-3
https://hdl.handle.net/21.11116/0000-000D-4CA3-621.11116/0000-000D-4CA5-421.11116/0000-000D-4CA6-3
Autor:
Jacob M. Wurlitzer, Aleksa Stanišić, Sebastian Ziethe, Paul M. Jordan, Kerstin Günther, Oliver Werz, Hajo Kries, Markus Gressler
Publikováno v:
Chemical Science. 13:9091-9101
Specificity profiling of a nonribosomal peptide synthetase of an early diverging fungus revealed high substrate flexibility. Feeding studies with click-functionalised amino acids enabled the production of fluorescent peptides targeting macrophages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e21040963a1763dc511030a860682433
https://doi.org/10.1039/d2sc00860b
https://doi.org/10.1039/d2sc00860b
Autor:
Markus Gressler, Hajo Kries
Publikováno v:
BIOspektrum. 28:481-483
Repurposing the enzymes in microbial metabolism such as nonribosomal peptide synthetases (NRPSs) is explored as a route towards better antibiotics. NRPSs are gigantic enzymatic assembly lines that form highly modified peptides from diverse building b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b307360a0c526bc2ca130908e478542
https://doi.org/10.1007/s12268-022-1810-x
https://doi.org/10.1007/s12268-022-1810-x
Autor:
Aleksa Stanišić, Annika Hüsken, Philipp Stephan, David L. Niquille, Jochen Reinstein, Hajo Kries
Publikováno v:
ACS Catalysis. 11:8692-8700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad94a3801a10c6cc9fe3bed56725508e
https://doi.org/10.1021/acscatal.1c01270
https://doi.org/10.1021/acscatal.1c01270
Autor:
Luka Raguž, Chia‐Chi Peng, Florentine U. N. Rutaganira, Thomas Krüger, Aleksa Stanišić, Theresa Jautzus, Hajo Kries, Olaf Kniemeyer, Axel A. Brakhage, Nicole King, Christine Beemelmanns
Publikováno v:
Angewandte Chemie. 134
The choanoflagellate Salpingoeca rosetta is an important model system to study the evolution of multicellularity. In this study we developed a new, modular, and scalable synthesis of sulfonolipid IOR-1A (six steps, 27 % overall yield), which acts as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40078d99698845105caa4ced83b55d4d
https://doi.org/10.1002/ange.202209105
https://doi.org/10.1002/ange.202209105
Autor:
Farzaneh Pourmasoumi, Sayantan De, Huiyun Peng, Felix Trottmann, Christian Hertweck, Hajo Kries
Publikováno v:
ACS chemical biology. 17(9)
Nonribosomal peptide synthetases (NRPSs) are a vast source of valuable natural products, and re-engineering them is an attractive path toward structurally diversified active compounds. NRPS engineering often requires heterologous expression, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd26867da713ad1237ed96280d4fe8a7
https://pubmed.ncbi.nlm.nih.gov/36044980
https://pubmed.ncbi.nlm.nih.gov/36044980
Autor:
Jakob Franke, Keishi Ishida, Hajo Kries, Georg Pohnert, Mie Ishida-Ito, Felix Trottmann, Christian Hertweck, Aleksa Stanišić
Publikováno v:
Angewandte Chemie-International Edition 59 (2020), Nr. 32
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Pathogenic bacteria of the Burkholderia pseudomallei group cause severe infectious diseases such as glanders and melioidosis. Malleicyprols were identified as important bacterial virulence factors, yet the biosynthetic origin of their cyclopropanol w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8366f9a0f88a8eb609e9062d86143ef1
https://doi.org/10.1002/anie.202003958
https://doi.org/10.1002/anie.202003958
Publikováno v:
ACS Catalysis. 10:4460-4464
Important reactions in biology and biocatalysis involve proton abstraction from carbon. When the resulting anionic charge is delocalized from carbon to an oxygen atom, these deprotonations can be c...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10a44c4dbfe8f0eb7bdb1b39baae01ad
https://doi.org/10.1021/acscatal.0c00575
https://doi.org/10.1021/acscatal.0c00575