Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hajime Sui"'
Autor:
Atsushi Hakura, Hajime Sui, Yuki Seki, Jiro Sonoda, Yusaku Yoshida, Hisayoshi Takagi, Shigeo Yokose, Tomonari Matsuda, Shoji Asakura, Takehiko Nohmi
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-13 (2023)
Abstract Background Chronic inflammation induces DNA damage and promotes cell proliferation, thereby increasing the risk of cancer. DNA polymerase κ (Pol κ), involved in translesion DNA synthesis, counteracts mutagenesis induced by inflammation in
Externí odkaz:
https://doaj.org/article/1d4b7a9880354c08aa90a424771b9d3a
Autor:
Shuichi Hamada, Miyuki Shigano, Satoru Kawakami, Maya Ueda, Hajime Sui, Katsuya Yamada, Soichiro Hagio, Ayaka Momonami, Akihisa Maeda, Yukari Terashima, Wakako Ohyama, Takeshi Morita, Makoto Hayashi
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Abstract Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity. In a collaborative stu
Externí odkaz:
https://doaj.org/article/c18356cee9e44b748aa005238a282ea6
Autor:
Masayuki Kato, Kei-ichi Sugiyama, Toshiro Fukushima, Yasuyoshi Miura, Takumi Awogi, Shigetomo Hikosaka, Kumiko Kawakami, Madoka Nakajima, Masato Nakamura, Hajime Sui, Kumiko Watanabe, Atsushi Hakura
Publikováno v:
Genes and Environment, Vol 40, Iss 1, Pp 1-13 (2018)
Abstract A large-scale study was conducted by multiple laboratories affiliated with the Japanese Environmental Mutagen Society and the Bacterial Mutagenicity Study Group to investigate possible proficiency indicators for the bacterial reverse mutatio
Externí odkaz:
https://doaj.org/article/0d3a2bfc233041b89a8cb8cb76e2bf8e
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 881:503513
N-Ethyl-N-nitrosourea (ENU) induces recessive mutations (RM) at a high frequency in male mouse primordial germ cells (PGCs) in a dose-dependent and stage-specific manner when administered during embryonic development as confirmed by a specific locus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e810770b5b4aad6a564f382602a06b7f
https://doi.org/10.1016/j.mrgentox.2022.503513
https://doi.org/10.1016/j.mrgentox.2022.503513
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 873
The forward or reverse processes of intragenic recombination (IGR), which occur through the addition or deletion of duplicated homologous exons of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03af0ee5201e3ee476360f993566cd45
https://pubmed.ncbi.nlm.nih.gov/35094814
https://pubmed.ncbi.nlm.nih.gov/35094814
Autor:
Ayaka Momonami, Soichiro Hagio, Satoru Kawakami, Akihisa Maeda, Hajime Sui, Miyuki Shigano, Katsuya Yamada, Takeshi Morita, Wakako Ohyama, Maya Ueda, Shuichi Hamada, Makoto Hayashi, Yukari Terashima
Publikováno v:
Genes and Environment
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity. In a collaborative study by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e819351cf59143d8aceafcbd6d3ec949
https://doi.org/10.1186/s41021-019-0128-5
https://doi.org/10.1186/s41021-019-0128-5
Publikováno v:
Environmental and molecular mutagenesis. 60(4)
In vitro studies indicate that DNA polymerase kappa (Polκ) is able to accurately and efficiently perform DNA synthesis using templates containing various types of DNA damage, including benzo[a]pyrene (BP)-induced N2 -deoxyguanosine adducts. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f15f08088a44bbd14de74e185d44d8f
https://pubmed.ncbi.nlm.nih.gov/30620413
https://pubmed.ncbi.nlm.nih.gov/30620413
Autor:
Yasuyoshi Miura, Takumi Awogi, Toshiro Fukushima, Masayuki Kato, Kumiko Watanabe, Kumiko Kawakami, Shigetomo Hikosaka, Atsushi Hakura, Kei-ichi Sugiyama, Madoka Nakajima, Hajime Sui, Masato Nakamura
Publikováno v:
Genes and Environment
Genes and Environment, Vol 40, Iss 1, Pp 1-13 (2018)
Genes and Environment, Vol 40, Iss 1, Pp 1-13 (2018)
A large-scale study was conducted by multiple laboratories affiliated with the Japanese Environmental Mutagen Society and the Bacterial Mutagenicity Study Group to investigate possible proficiency indicators for the bacterial reverse mutation test wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3251c0c39f4857b57928cd9534c27d19
http://europepmc.org/articles/PMC5883876
http://europepmc.org/articles/PMC5883876
Autor:
Hajime Sui, Yoshiaki Saito, Kenji Usumi, Yuzuki Nakagawa, Fumiaki Kumagai, Tomoyasu Toyoizumi, Ryo Ohta, Kohji Yamakage
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :104-113
As part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiative international validation study of the in vivo rat alkaline comet assay, we examined the ability of acrylonitrile, 9-aminoacridine hydrochloride monohydrate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f16085806c85a1f682f8ef9ab06865
https://doi.org/10.1016/j.mrgentox.2015.04.001
https://doi.org/10.1016/j.mrgentox.2015.04.001
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :81-84
The repeated-dose liver micronucleus (RDLMN) assay has the potential to detect liver carcinogens and can be integrated into general toxicological studies. In this study, thioacetamide (TAA) was tested in 14- and 28-day RDLMN assays to assess the perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadc7ab64a18b7699df7417dfc224f8a
https://doi.org/10.1016/j.mrgentox.2014.10.001
https://doi.org/10.1016/j.mrgentox.2014.10.001