Inhibition of P-selectin-mediated cell adhesion by a sulfated derivative of sialic acid

Autor: Tsutomu Tsuji, Tomonori Shodai, Sanae Kudo, Saotomo Itoh, Hajime Shimazu, Masaki Terada, Shuji Fujita, Junsuke Suzuki

Publikováno v: Biochemical and biophysical research communications. 312(3)

P-selectin, a carbohydrate-binding cell adhesion molecule expressed on activated endothelial cells and platelets, plays a key role in the recruitment of leukocytes to inflammatory and hemorrhagic sites. It simultaneously recognizes a sialic acid-cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df404c77be09e97fb6a9525a82c22276
https://pubmed.ncbi.nlm.nih.gov/14680834

GENERAL SESSION

Autor: Fumie SASAKI, Shiro NAKAGAWA, Chiharu SUEMATSU, Tajimi HIROHATA, Eiichi SHIMIZU, Tetsuzo KUMAMOTO, Terutaka FUKAYA, Isao YAMAMOTO, Naoki KAGEYAMA, Takuma SAITO, Kimiya SUGIMURA, Akira MIZUTANI, Kazuhiro YOSHIKAWA, Koichi IIJIMA, Yoshio AKAGI, Yasuhiko IBATA, Yutaka Sano, A.S. DABHOLKAR, K. OGAWA, Kiminao MIZUKAWA, Keisuke SHIMIZU, Tadao MATSUURA, Yoshiyuki AOKI, Tadashi OFUJI, Nagayasu OTSUKA, Ko SAHASHI, Hidetoshi FUKUNAGA, Fumúko YAZIMA, Masanori UONO, Koichi INOUE, Tatsunori NISHI, Shigeto KANDA, Akira Kawaoi, Tadao OKANO, TAKANORI AMAKAWA, RYUNOSUKE MIYAZAKI, Mamoru SANO, Hiromi KEINO, Fumiaki NISHIYAMA, Toshiro SHIODA, Tatsuro IRIMURA, Hiroshi HIRANO, N. Morimoto, S. Shimizu, K. Yamada, Yoshimasa KANEDA, Norio TAKIGUCHI, Emiyo MACHINAKA, Sotokichi MORII, Koji KAMI, Tadao MITSUI, Toshio SUZUKI, Shohei YAMASHIMA, Vinci MIZUHIRA, Tsugio AMEMIYA, Satoki UENO, Toshiyuki YAMAGUCHI, Shunta HIROSE, Zenzi IWASA, Masaaki HIROSE, Katsuhisa SHINDO, A.K.A. RAZZAQ, Minoru SHIMIZU, Takatoshi KAWASAKI, Hirotoshi NAGAI, Tokuhiro MIYAMOTO, M. SHIMAZAKI, T. MITSUHASHI, N. ASAI, T. SASAKI, R. HASEGAWA, T. AOBA, Masanobu GAN, Akira IKEDA, Masatoyo Akiyoshi, Hideo Tamura, Saburo Yano, Hozumi Nakada, Kiichi Sato, Osami NADA, Kazuho HIRATA, Kyoko TAKENO, Yoshinori WATANABE, Terukazu TAKANO, Fujio NUMANO, M. Kobayashi, T. Takahashi, K. Moriya, T. Shimamoto, Y. Shioya, H. Fujino, F. Numano, Hiroshi SUZUKI, Takao OHISHI, Shaw WATANABE, Atsuo MIKATA, Masa-oki YAMADA, Hisashi TAKEUCHI, Ken FUJIMORI, Naoyuki Maruo, Takuji Isemura, Masaru Fukuda, Setsuya Fujita, Tateo DAIMON, Kazuko UCHIDA, F. Murata, Y. Momose, T. Nagata, Sachiko KAKUTA, Kouhei MORIMOTO, Shohei YAMASHINA, Shigeyoshi KAMO, Ben HATAI, Kensuke WATANABE, Takao OHISI, Shaw WATAMABE, Keizo KAGEYAMA, Yoshio ASO, T. ONO, N. YAMAMOTO, K. YASUDA, Hirohiko IWATSUKI, W. Allen Shannon, Yoshinobu Hoshino, Arnold M. Seligman, Takuro SUZUKI, Masaru KIMURA, Kazuto NOKUBI, Takeshi MURAKI, Morio KATO, Hiroshi KIMURA, Masaya TOHYAMA, Toshihiro MAEDA, Nobuo SHIMIZU, Jiro SENO, Kotaro OSAWA, Ryuei MAEDA, Tsutomu Koide, Toru Kameya, Yukio Shimosato, Yasuo KISHINO, Toshiko SUMI, Muneaki ABE, Hajime AOE, Kazuhisa TAKETA, Masatoshi UEDA, Kiyowo KOSAKA, Akira TANAKA, Haruo FUKUDA, Motohiko ITO, Haruhiko MIYAYAMA, William H. FISHMAN, Kosuke CHIDA, Noboru YAMAMOTO, Kenjiro YASUDA, Shinsuke KANAMURA, Kazuo OGAWA, M. KAKO, M. TORII, H. SUZUKI, G. TODA, K. MIYAKE, K. OKAZAKI, T. ODA, Osamu Teranobu, Yukio Sumitani, Keiichi Shimada, Masaho Maeda, Taketoshi Sugiyama, Kanji KISHI, Katsumi NISHIJIMA, Toshihiro ISHIDA, Takahito NAGATSUKA, Masakazu TSUNASHIMA, Satimaru SENO, Toshio YOSHIOKA, Kunio TAKAOKA, Akitoshi SUGIMOTO, Masao OHYUMI, Tadao TAKEUCHI, S. Yamashita, Shotaro HISAMITSU, Haruaki TAKEUCHI, Tetsuji NAGATA, Fusayoshi MURATA, Ken SAKAI, Michro OKABE, Komyo ETO, Kenichi TAKAYA, Keiko GOTO, Tomotoshi AKEMATSU, Hajime SHIMAZU, Yoshio KANO, Yozo KAWAKITA, Hajime SUGIHARA, Yoshikiyo BANDO, Kazuo Nakanishi, Akihiro Shima

Publikováno v: ACTA HISTOCHEMICA ET CYTOCHEMICA. 9:88-104

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ff2b29972a76007c5cf4c2032583c10
https://doi.org/10.1267/ahc.9.88

Rectal delivery of antiinflammatory drugs. II. The influence of basic amino acid salts on rectal absorption of diclofenac

Autor: Ichiro Makita, Hajime Shimazu, Teruo Murakami, Tohru Nakata, Harumasa Toya, Hideya Yaginuma, Masaru Yamazaki, Akira Kamada

Publikováno v: Chemical and Pharmaceutical Bulletin. 29:3326-3333

Rectal absorption of diclofenac (DC) and its salts with sodium (DCNa), L-arginine (DC-Arg), L-lysine (DC-Lys), and L-histidine (DC-His) was studied in dogs, rabbits and rats. Plasma levels of unchanged DC were measured by high performance liquid chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7b4c5180b5c081eeb6f92585fb7600
https://doi.org/10.1248/cpb.29.3326

PATHOLOGICAL CONSIDERATION ON THE TOXICITY OF 4-ETHOXY-2-METHYL-5-MORPHOLINO-3(2H)-PYRIDAZINONE (M73101) IN RATS

Autor: Tsuneyoshi Tanabe, Mieko Iwata, Hiroko Togashi, Kazue Hiraga, Kotaro Shimpo, Noriko Mori, Masayo Takahashi, Hajime Shimazu, Tsuneo Kosazuma

Publikováno v: The Journal of Toxicological Sciences. 4:139-161

By using male and female JCL:SD rats, the subacute toxicity and recovery from toxic phenomena were tested on M73101, which was newly developed as an analgesic and anti-inflammatory drug. The drug was compulsively administered perorally in doses of 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9a7c812ee8b6ba102f0ce417bcce247
https://doi.org/10.2131/jts.4.139

INTRAVENOUS CHRONIC TOXICITY OF LENTINAN IN RATS : 6-MONTH TREATMENT AND 3-MONTH RECOVERY

Autor: Ichiro Makita, Masaya Takeuchi, Shinichi Ohkuma, Takashi Hashi, Kotaro Shinpo, Hiroyuki Tanigawa, Hajime Shimazu, Kyoichi Takeda, Yukifumi Kokuba, Takeshi Yamazoe, Chiaki Onodera

Publikováno v: The Journal of Toxicological Sciences. 5:33-57

Chronic toxicity of lentinan was studied in male and female JCL:SD rats. Lentinan was given intravenously into tail vein. Dosage levels employed were 0 (5% mannitol), 0.01, 0.1, 1 (with or without dextran), and 10 mg/kg/day for 6 months in a volume o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45f80cc59a7c4765afcc0b26771d74a5
https://doi.org/10.2131/jts.5.supplement_33