Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hajime Nakahara"'
Autor:
Munekiyo Kaneko, Akito Yatani, Mitsuhiro Yokoyama, Yasunori Ichikawa, Hajime Nakahara, Osamu Matsuo, Kazuki Matsui, Teruo Sakurama, Shigeru Ueshima
Publikováno v:
Journal of Cardiovascular Pharmacology. 28:571-575
Tissue-type plasminogen activator (t-PA) can occur in two different forms, single- and two-chain t-PA. Such a difference in structure of the t-PA molecule may induce different biological functions. We compared the thrombolytic efficacy of single-chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e38553fd7345edf0dcb60c0aee24370
https://doi.org/10.1097/00005344-199610000-00015
https://doi.org/10.1097/00005344-199610000-00015
Autor:
Hajime Nakahara, Masako Uchida
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 115(4)
A number of reports have characterized cetirizine as a potent histamine H1-receptor antagonist possessing inhibitory effects on eosinophil chemotaxis. In clinical pharmacological tests, cetirizine markedly reduced wheal and flare responses induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595d4a6b57e63e502be30e4029212a41
https://pubmed.ncbi.nlm.nih.gov/10876807
https://pubmed.ncbi.nlm.nih.gov/10876807
Autor:
Shoichi Imai, Takafumi Nagatomo, Yoshito Nakagawa, Setsuko Sasaki, Hajime Nakahara, Hiroshi Tsuchihashi
Publikováno v:
Japanese Journal of Pharmacology. 37:181-187
To characterize the alpha 1-adrenoceptors in the dog aorta and the rat brain and to assess the antagonistic potencies of various chemicals inclusive of newly synthesized ones, radioligand binding assays were performed, and the potencies thus obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807effdd6e3969465f659d1737b2c297
https://doi.org/10.1254/jjp.37.181
https://doi.org/10.1254/jjp.37.181
Publikováno v:
Japanese Journal of Pharmacology. 40:381-387
Analysis of the relative magnitude of the positive inotropic and chronotropic effects and the coronary vasodilating effects of amrinone conducted in the canine heart-lung preparation with a support dog in comparison with those of dobutamine demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cdfe8d02f8b2f63670f08ff429d27c
https://doi.org/10.1254/jjp.40.381
https://doi.org/10.1254/jjp.40.381
Publikováno v:
Drugs. 36:10-19
The acute antihypertensive effects and possible underlying mechanisms of 3 beta-adrenergic-blocking drugs with alpha-blocking activity, i.e. labetalol, drugs with alpha-blocking activity, i.e. labetalol, nipradilol and arotinolol, were studied in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea4f422029a7a133aae0bd3cbfd4421
https://doi.org/10.2165/00003495-198800366-00004
https://doi.org/10.2165/00003495-198800366-00004
Autor:
Mikio Nakazawa, Keisuke Takeda, Kazuki Matsui, Yoshito Nakagawa, Takahito Kimura, Hirokuni Tamatsu, Hajime Nakahara, Tomie Kawada, Shoichi Imai
Publikováno v:
Journal of Cardiovascular Pharmacology. 7:862-868
In the canine heart-lung preparation (HLP) and the anesthetized open-chest dog, both 8-(Benzylthio)-N6-n-butyl-cyclic AMP (BTB-cyclic AMP) (10 times more potent) and dibutyryl-cyclic AMP (DB-cyclic AMP) produced a definite positive inotropic effect (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d07be0430b0db79a6650d649a50ba97
https://doi.org/10.1097/00005344-198509000-00008
https://doi.org/10.1097/00005344-198509000-00008
Autor:
Takafumi NAGATOMO, Hiroshi TSUCHIHASHI, Miyuki SASAKI, Yoshito NAKAGAWA, Hajime NAKAHARA, Shoichi IMAI
Publikováno v:
Japanese Journal of Pharmacology. 34:249-254
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f4bb57fedbe0d71ca21079c25326679
https://doi.org/10.1016/s0021-5198(19)52354-x
https://doi.org/10.1016/s0021-5198(19)52354-x
Publikováno v:
Japanese Heart Journal. 25:827-829
Effects of β-blockers on the peripheral sympatheic adrenergic nervous system were studied in atropinized pithed rats under curarized condition using the rise of the diastolic blood pressure produced by stimulation of the spinal nerves as a measure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6076c44a910e6bab5ac26ddbeefef66
https://doi.org/10.1536/ihj.25.827
https://doi.org/10.1536/ihj.25.827
Publikováno v:
Japanese journal of pharmacology. 39(4)
Acute hypotensive effects and the mechanisms of three beta-adrenergic blocking drugs with alpha-blocking activity were studied in comparison with those of prazosin, propranolol and hydralazine in the conscious spontaneously hypertensive rat (SHR). Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdcfc13198b4edbe434b8f332f5b253f
https://pubmed.ncbi.nlm.nih.gov/2419613
https://pubmed.ncbi.nlm.nih.gov/2419613
Publikováno v:
Japanese journal of pharmacology. 39(4)
In pithed rats two recently-introduced beta-blockers, nipradilol and arotinolol, as well as labetalol shifted the pressor dose-response curve for phenylephrine to the right. Labetalol and arotinolol did not modify the pressor dose-response curve for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f89077c76de22bf2d27bbf2c6de2e6
https://pubmed.ncbi.nlm.nih.gov/2419612
https://pubmed.ncbi.nlm.nih.gov/2419612