Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Hajime Kotaki"'
Autor:
Mio Ogino, Ken-ichi Miyamoto, Mariko Asahi, Mai Ishikawa, Takuya Hirao, Harumi Yamada, Hiroshi Ito, Yoshimichi Sai, Hajime Kotaki, Iori Hirosawa
Publikováno v:
Biopharmaceutics & Drug Disposition. 35:207-217
Clenbuterol is a long-acting β2-adrenoceptor agonist and bronchodilator that is used for the treatment of asthma, but the desired activities reside almost exclusively in the (-)-R-enantiomer. This study examined enantioselectivity in the disposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87e16640886e140db5b0146f3fe4483c
https://doi.org/10.1002/bdd.1885
https://doi.org/10.1002/bdd.1885
Autor:
Tokue Imanari, Mitsuru Ueki, Hajime Kotaki, Yuko Eto, Masataka Tajima, Shigemitsu Saito, Yasunari Mano, Naoki Onomura, Iori Hirosawa, Kaori Ohuchi, Yoshinori Kato, Noboru Shono, Harumi Yamada, Mariko Asahi
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 39:140-147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2aa4b188ddab567c5b1d66672f0c386
https://doi.org/10.5649/jjphcs.39.140
https://doi.org/10.5649/jjphcs.39.140
Autor:
Daisuke Sato, Yasunari Mano, Masataka Tajima, Kiichi Nakajima, Iori Hirosawa, Hajime Kotaki, Kuniaki Ebara, Kaori Ohuchi, Yoshinori Kato, Fumito Tsuchiya, Aya Higuchi, Kyoko Iwata, Harumi Yamada, Mariko Asahi
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 38:599-608
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86d55f79597270ec5fa98f13e71962f
https://doi.org/10.5649/jjphcs.38.599
https://doi.org/10.5649/jjphcs.38.599
Autor:
Yasuhiko Yamada, Yasufumi Sawada, Hajime Kotaki, Masako Atsumi, Erika Sugiyama, Tatsuji Iga, Hitoshi Sato, Junichi Kawakami
Publikováno v:
Synapse. 50:110-116
Bromocriptine is a selective agonist for dopamine D2-receptors and is used in the treatment of Parkinson's disease. In this study, we performed pharmacokinetic and pharmacodynamic (PK/PD) analyses of the antiparkinsonian effect of bromocriptine and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a2411d4042edd9bf62ba00630250fa
https://doi.org/10.1002/syn.10248
https://doi.org/10.1002/syn.10248
Autor:
Haruaki Nakaya, Noriko Uemura, Hitoshi Sato, Michiko Hirota, Tatsuji Iga, Hajime Kotaki, Erika Hanada, Hisakazu Ohtani, Yasuhiko Yamada
Publikováno v:
Journal of Pharmacy and Pharmacology. 55:995-1002
Disopyramide, a class la antiarrhythmic agent, has been reported to induce torsades de pointes (TdP) associated with excessive QT prolongation in electrocardiogram (ECG), especially when concomitantly administered with erythromycin, a macrolide antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf33568d14f3a942a4297e22f88ae208
https://doi.org/10.1211/0022357021459
https://doi.org/10.1211/0022357021459
Autor:
Mika Matsumoto, Tatsuji Iga, Yoshie Fujinuma, Michiteru Ohtani, Katsuyoshi Uchino, Hitoshi Nakamura, Hajime Kotaki
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 27:491-494
In the present study, we investigated the effect of inter-individual variation and dispensing experience as a factor of variation when mixing digoxin powders.Sixteen of the post-graduate trainees (non-experienced group) who entered the Department of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fee96945585ddccf3e9000c3b7152c
https://doi.org/10.5649/jjphcs.27.491
https://doi.org/10.5649/jjphcs.27.491
Autor:
Yasufumi Sawada, Chieko Taninaka, Hisakazu Ohtani, Tatsuji Iga, Hitoshi Sato, Hajime Kotaki, Erika Hanada
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:2630-2637
In order to evaluate the arrhythmogenic potency of macrolide antibiotics in a quantitative manner, we analyzed the influence of clarithromycin (CAM), roxithromycin (RXM), and azithromycin (AZM) on Q-T intervals from pharmacokinetic and pharmacodynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4d17e1a85d69b57f0ba2bca8055b9c
https://doi.org/10.1128/aac.44.10.2630-2637.2000
https://doi.org/10.1128/aac.44.10.2630-2637.2000
Publikováno v:
Biopharmaceutics & Drug Disposition. 20:271-276
In the initial phase of clinical studies, it was shown that E3040, a new type of anti-inflammatory drug, reduced plasma uric acid levels. The present study describes a comparison of the excretion of uric acid in the proximal tubules of the kidney aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d608c65f10ad9a7be236f1779c3aae
https://doi.org/10.1002/(sici)1099-081x(199907)20:5<271::aid-bdd185>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199907)20:5<271::aid-bdd185>3.0.co
Publikováno v:
Biopharmaceutics & Drug Disposition. 20:101-106
Ebastine (EBS), a novel nonsedative antiallergic agent, is similar to terfenadine in its chemical structure. However, clinical arrhythmogenicity of EBS remains controversial. In this study, we evaluated the possible arrhythmogenic potency of EBS as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0f38aeefc67e58df5b6cfb39ac6a72
https://doi.org/10.1002/(sici)1099-081x(199903)20:2<101::aid-bdd160>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199903)20:2<101::aid-bdd160>3.0.co
Publikováno v:
Journal of Pharmaceutical Sciences. 88:234-240
Disopyramide (DP) is known to induce QT prolongation and Torsades de Pointes (TdP) when administered concomitantly with erythromycin (EM). To define and evaluate quantitatively the arrhythmogenic risk of the concomitant administration of DP and EM, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cd8d49522f73492bc2370efd1ab6ad
https://doi.org/10.1021/js980256r
https://doi.org/10.1021/js980256r