Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hajime Hirasawa"'
Autor:
Hajime Hirasawa
Publikováno v:
Cellular Physiology and Biochemistry, Vol 58, Iss 2, Pp 172-181 (2024)
Background/Aims: Extracellular acidic conditions impair cellular activities; however, some cancer cells drive cellular signaling to adapt to the acidic environment. It remains unclear how ovarian cancer cells sense changes in extracellular pH. This s
Externí odkaz:
https://doaj.org/article/97886bf88c184c54bcca9ab5883114ba
Autor:
Hiromasa Satoh, Fuminobu Tamalu, Narumi Hirosawa, Hajime Hirasawa, Mitsuo Nagane, Ryohei Saito, Shu-Ichi Watanabe, Naofumi Miwa
Publikováno v:
Medical Science Educator. 32:641-648
The physiological practice course at Saitama Medical University provides students with the opportunity to learn physiological principles through wet labs and discussions. To develop a more effective method for maximizing learning outcomes, we extende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d465fa305728c5e1938f97bbdc47bc
https://doi.org/10.1007/s40670-022-01563-4
https://doi.org/10.1007/s40670-022-01563-4
Autor:
Tomoyuki Araki, Masaru Nagashima, Hajime Hirasawa, Fuminobu Tamalu, Yukiko Katagiri, Naofumi Miwa
Publikováno v:
Biochemical and biophysical research communications. 637
Aberrant DNA methylation is associated with oncogenesis of various human cancers, including pancreatic cancer (PC). PC is the seventh most common cancer, and obesity is a known high-risk factor. However, whether obesity influences DNA methylation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe6e99256546775f71fa71f6c15b563
https://pubmed.ncbi.nlm.nih.gov/36375250
https://pubmed.ncbi.nlm.nih.gov/36375250
Publikováno v:
European Journal of Neuroscience. 53:1428-1440
The network mechanisms underlying how inhibitory circuits regulate ON- and OFF-responses (the b- and d-waves) in the electroretinogram (ERG) remains unclear. The purpose of this study was to investigate the contribution of inhibitory circuits to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b172f657b921e1a223b4976ffdba6f9a
https://doi.org/10.1111/ejn.15054
https://doi.org/10.1111/ejn.15054
Publikováno v:
Biochemical and biophysical research communications. 570
Implantation is a highly organized process that involves an interaction between a competent blastocyst and a receptive uterus. Despite significant research efforts, the molecular mechanisms governing this complex process remain elusive. Here, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e98667a9bdbd54d3f7da8ab651d8a7
https://pubmed.ncbi.nlm.nih.gov/34311201
https://pubmed.ncbi.nlm.nih.gov/34311201
Autor:
Hajime Hirasawa, Mineto Morita, Ken Takamatsu, Masaru Nagashima, Naofumi Miwa, Yukiko Katagiri
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Aberrant DNA methylation is associated with the oncogenesis of a variety of human cancers, including endometrial cancer (EC), the seventh most common cancer among women. Obesity is known to be a high-risk factor for EC; however, whether obesity influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71dcc7afabedf38047a3a109424f4320
http://link.springer.com/article/10.1038/s41598-019-42840-4
http://link.springer.com/article/10.1038/s41598-019-42840-4
Publikováno v:
Journal of Neurophysiology. 102:146-158
GABA release by dopaminergic amacrine (DA) cells of the mouse retina was detected by measuring Cl−currents generated by isolated perikarya in response to their own neurotransmitter. The possibility that the Cl−currents were caused by GABA release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e480dbbe6935a29a285c197ec458e2
https://doi.org/10.1152/jn.00130.2009
https://doi.org/10.1152/jn.00130.2009
In the mouse retina, dopaminergic amacrine (DA) cells synthesize both dopamine and GABA. Both transmitters are released extrasynaptically and act on neighbouring and distant retinal neurons by volume transmission. In simultaneous recordings of dopami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb05f9b6de39ff6bac4841cbf71d3e63
https://europepmc.org/articles/PMC4455755/
https://europepmc.org/articles/PMC4455755/
Autor:
Akimichi Kaneko, Hajime Hirasawa
Publikováno v:
The Journal of General Physiology
Feedback from horizontal cells (HCs) to cone photoreceptors plays a key role in the center-surround–receptive field organization of retinal neurons. Recordings from cone photoreceptors in newt retinal slices were obtained by the whole-cell patch-cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c70368245f10455e24f278ecf805cc
https://doi.org/10.1085/jgp.200308863
https://doi.org/10.1085/jgp.200308863