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of 3
pro vyhledávání: '"Hajar Dauleh"'
Autor:
Hoda Gad, Idris Mohammed, Hajar Dauleh, Maheen Pasha, Tara Al-Barazenji, Khalid Hussain, Rayaz A. Malik
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Melanocortin 4 receptor (MC4R) mutations are the commonest cause of monogenic obesity through dysregulation of neuronal pathways in the hypothalamus and prefrontal cortex that regulate hunger and satiety. MC4R also regulates neuropathic pain pathways
Externí odkaz:
https://doaj.org/article/69943c9323e14e789399a727c672d5c5
Autor:
Idris Mohammed, Senthil Selvaraj, Wesam S. Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R. Saraiva, Mashael Al-Shafai, Khalid Hussain
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16361 (2023)
The leptin–melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The MC4R gene plays a central role in leptin–melanocortin sign
Externí odkaz:
https://doaj.org/article/cfec28209f40430798c9a49b91d9db91
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Prader–Willi syndrome (PWS) is a genetic disorder caused by the lack of expression of genes on the paternally inherited chromosome region 15q11.2-q13. It is a multisystem disorder that is characterized by severe hypotonia with poor suck and feeding
Externí odkaz:
https://doaj.org/article/8107084a5485417a92e410ebf0b5ab3e