Development of Nonpeptidic Inverse Agonists of the Ghrelin Receptor (GHSR) Based on the 1,2,4-Triazole Scaffold.

Autor: Haj Salah KB; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Maingot M; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Blayo AL; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., M'Kadmi C; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Damian M; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Mary S; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Cantel S; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Neasta J; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Oiry C; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Péraldi-Roux S; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Fernandez G; Laboratory of Neurophysiology of the Multidisciplinary Institute of Cell, La Plata, Buenos Aires 1900, Argentina., Romero GG; Laboratory of Neurophysiology of the Multidisciplinary Institute of Cell, La Plata, Buenos Aires 1900, Argentina., Perello M; Laboratory of Neurophysiology of the Multidisciplinary Institute of Cell, La Plata, Buenos Aires 1900, Argentina., Marie J; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Banères JL; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Fehrentz JA; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France., Denoyelle S; IBMM, Univ Montpellier, CNRS, ENSCM, Faculty of Pharmacy, 34000 Montpellier, France.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Oct 08; Vol. 63 (19), pp. 10796-10815. Date of Electronic Publication: 2020 Sep 21.