Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Haiying Que"'
Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses
Autor:
Li Chen, Wenyan Ren, Hong Lei, Jiayu Wang, Haiying Que, Dandan Wan, Aqu Alu, Dandan Peng, Minyang Fu, Weiqi Hong, Yuhe Huang, Xiangrong Song, Guangwen Lu, Xiawei Wei
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101066- (2024)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has decreased the efficacy of SARS-CoV-2 vaccines in containing coronavirus disease 2019 (COVID-19) over time, and booster vaccination strategies are urgently nece
Externí odkaz:
https://doaj.org/article/de498c355822410c9c314b98a69a739d
Autor:
Weiqi Hong, Hong Lei, Dandan Peng, Yuhe Huang, Cai He, Jingyun Yang, Yanan Zhou, Jian Liu, Xiangyu Pan, Haiying Que, Aqu Alu, Li Chen, Jiayuan Ai, Furong Qin, Binhan Wang, Danyi Ao, Zhen Zeng, Ying Hao, Yu Zhang, Xiya Huang, Chunjun Ye, MinYang Fu, Xuemei He, Zhenfei Bi, Xuejiao Han, Min Luo, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Lu Chen, Xikun Zhou, Wei Wang, Guangwen Lu, Guobo Shen, Li Yang, Jinliang Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Qiangming Sun, Shuaiyao Lu, Youchun Wang, Ping Cheng, Xiawei Wei
Publikováno v:
MedComm, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Urgent research into innovative severe acute respiratory coronavirus‐2 (SARS‐CoV‐2) vaccines that may successfully prevent various emerging emerged variants, particularly the Omicron variant and its subvariants, is necessary. Here, we
Externí odkaz:
https://doaj.org/article/5f86cf25f441434681a4705fbc53e5ee
Autor:
Haiying Que, Weiqi Hong, Tianxia Lan, Hao Zeng, Li Chen, Dandan Wan, Zhenfei Bi, Wenyan Ren, Min Luo, Jingyun Yang, Cai He, Ailing Zhong, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract For coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), 15–30% of patients are likely to develop COVID-19-related acute respiratory distress syndrome (ARDS). There are still few effe
Externí odkaz:
https://doaj.org/article/0b63e69aba434510838814d61e30b2d8
Autor:
Cai He, Jingyun Yang, Weiqi Hong, Zimin Chen, Dandan Peng, Hong Lei, Aqu Alu, Xuemei He, Zhenfei Bi, Xiaohua Jiang, Guowen Jia, Yun Yang, Yanan Zhou, Wenhai Yu, Cong Tang, Qing Huang, Mengli Yang, Bai Li, Jingmei Li, Junbin Wang, Haiying Que, Li Chen, Wenyan Ren, Dandan Wan, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Zhaoming Su, Yuquan Wei, Xiaobo Cen, Yoshimasa Tanaka, Xiangrong Song, Shuaiyao Lu, Xiaozhong Peng, Guangwen Lu, Xiawei Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The SARS-CoV-2 Omicron variant has quickly become the predominant circulating variant, due to the high transmissibility and immune escape. Here, the authors develop a trimeric protein vaccine candidate and show a sustained humoral immune response, an
Externí odkaz:
https://doaj.org/article/6931d87e1b9f415882b4ac5ac20fee24
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Cancer is a severe disease that substantially jeopardizes global health. Although considerable efforts have been made to discover effective anti-cancer therapeutics, the cancer incidence and mortality are still growing. The personalized anti
Externí odkaz:
https://doaj.org/article/e09972130b9d4806bab190196394c36c
Autor:
Zhenfei Bi, Weiqi Hong, Haiying Que, Cai He, Wenyan Ren, Jingyun Yang, Tianqi Lu, Li Chen, Shuaiyao Lu, Xiaozhong Peng, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The development of animal models for COVID-19 is essential for basic research and drug/vaccine screening. Previously reported COVID-19 animal models need to be established under a high biosafety level condition for the utilization of live SA
Externí odkaz:
https://doaj.org/article/6972ecfacb72457b9cae2f508bb948eb
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Currently, SARS-CoV-2 has caused a global pandemic and threatened many lives. Although SARS-CoV-2 mainly causes respiratory diseases, growing data indicate that SARS-CoV-2 can also invade the central nervous system (CNS) and peripheral nervo
Externí odkaz:
https://doaj.org/article/d8bcff38e3284e018f0e9df47a448382
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1372 (2022)
The lymphatic system plays an indispensable role in humoral balance, lipid metabolism, and immune regulation. The lymph nodes (LNs) are known as the primary sites of tumor metastasis and the metastatic LNs largely affected the prognosis of the patien
Externí odkaz:
https://doaj.org/article/e81941c834a94b8d946ec17c4f82c59b
Autor:
Haiying Que, Xiawei Wei, Li Chen, Tianxia Lan, Yuquan Wei, Jingyun Yang, Cai He, Dandan Wan, Weiqi Hong
Publikováno v:
Nano Letters. 21:7960-7969
Toll-like receptor (TLR) agonists as the potent stimulants of an innate immune system hold promises for applications in anticancer immunotherapy. However, most of them are limited in the clinical translation due to the uncontrolled systemic inflammat
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1877(5)
Neutrophils are the frontline cells in response to microbial infections and are involved in a range of inflammatory disorders in the body. In recent years, neutrophils have gained considerable attention in their involvement of complex roles in tumor