Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Haiyi Lou"'
Autor:
Kai Yuan, Xumin Ni, Chang Liu, Yuwen Pan, Lian Deng, Rui Zhang, Yang Gao, Xueling Ge, Jiaojiao Liu, Xixian Ma, Haiyi Lou, Taoyang Wu, Shuhua Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Existing methods to identify the presence of DNA from other hominin species can be limited in the ability to accurately estimate introgression waves, or can only be applied to specific populations. Here, the authors have developed a generalizable met
Externí odkaz:
https://doaj.org/article/c7c262016bde4abeb8cd9fb10f2306c2
Autor:
Lian Deng, Haiyi Lou, Xiaoxi Zhang, Bhooma Thiruvahindrapuram, Dongsheng Lu, Christian R. Marshall, Chang Liu, Bo Xie, Wanxing Xu, Lai-Ping Wong, Chee-Wei Yew, Aghakhanian Farhang, Rick Twee-Hee Ong, Mohammad Zahirul Hoque, Abdul Rahman Thuhairah, Bhak Jong, Maude E. Phipps, Stephen W. Scherer, Yik-Ying Teo, Subbiah Vijay Kumar, Boon-Peng Hoh, Shuhua Xu
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Recent advances in genomic technologies have facilitated genome-wide investigation of human genetic variations. However, most efforts have focused on the major populations, yet trio genomes of indigenous populations from Southeast
Externí odkaz:
https://doaj.org/article/bb937d71dadd4e879a4627ac700dacc5
Autor:
Chao Zhang, Yan Lu, Qidi Feng, Xiaoji Wang, Haiyi Lou, Jiaojiao Liu, Zhilin Ning, Kai Yuan, Yuchen Wang, Ying Zhou, Lian Deng, Lijun Liu, Yajun Yang, Shilin Li, Lifeng Ma, Zhiying Zhang, Li Jin, Bing Su, Longli Kang, Shuhua Xu
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-18 (2017)
Abstract Background The genetic relationships reported by recent studies between Sherpas and Tibetans are controversial. To gain insights into the population history and the genetic basis of high-altitude adaptation of the two groups, we analyzed gen
Externí odkaz:
https://doaj.org/article/c29cbcd8434c42b59ce466bb30915db4
Autor:
Haiyi Lou, Shilin Li, Yajun Yang, Longli Kang, Xin Zhang, Wenfei Jin, Bailin Wu, Li Jin, Shuhua Xu
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27341 (2011)
It has been shown that the human genome contains extensive copy number variations (CNVs). Investigating the medical and evolutionary impacts of CNVs requires the knowledge of locations, sizes and frequency distribution of them within and between popu
Externí odkaz:
https://doaj.org/article/2ede9c6450094eba80647c303aaab264
Publikováno v:
Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56b5e53da0187c31d064278eea18f121
https://doi.org/10.1117/12.2669536
https://doi.org/10.1117/12.2669536
Autor:
Yimin, Wang, Yunchao, Ling, Jiao, Gong, Xiaohan, Zhao, Hanwen, Zhou, Bo, Xie, Haiyi, Lou, Xinhao, Zhuang, Li, Jin, Shaohua, Fan, Guoqing, Zhang, Shuhua, Xu
Publikováno v:
Nucleic acids research.
Structural variations (SVs) play important roles in human evolution and diseases, but there is a lack of data resources concerning representative samples, especially for East Asians. Taking advantage of both next-generation sequencing and third-gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b55aa35cb636efe330f9d8caeb1b19
https://pubmed.ncbi.nlm.nih.gov/36243989
https://pubmed.ncbi.nlm.nih.gov/36243989
Trypsin is an important enzyme secreted by the pancreas for digesting proteins. The precursors of major human trypsin are encoded by trypsinogen genes PRSS1 and PRSS2. Here, we leveraged multi-omic data to study their evolutionary and functional impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b2ca5cf5b934c4cee89125647f04a8
https://doi.org/10.1101/2022.08.08.22278454
https://doi.org/10.1101/2022.08.08.22278454
Publikováno v:
Gut. 72(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87c06519a656bb071a310269aa705948
https://pubmed.ncbi.nlm.nih.gov/35288441
https://pubmed.ncbi.nlm.nih.gov/35288441
Autor:
Jiaojiao Liu, Yang Gao, Xixian Ma, Taoyang Wu, Rui Zhang, Kai Yuan, Haiyi Lou, Xueling Ge, Xumin Ni, Lian Deng, Chang Liu, Yuwen Pan, Shuhua Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
We developed a method, ArchaicSeeker 2.0, to identify introgressed hominin sequences and model multiple-wave admixture. The new method enabled us to discern two waves of introgression from both Denisovan-like and Neanderthal-like hominins in present-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be501bd67c5ad79c8ae91e131516a01
https://doi.org/10.1038/s41467-021-26503-5
https://doi.org/10.1038/s41467-021-26503-5
Publikováno v:
Gut; Jan2023, Vol. 72 Issue 1, p210-212, 13p