Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Haiyan Ying"'
E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation
Autor:
Guilin Qiao, Haiyan Ying, Yixia Zhao, Yanran Liang, Hui Guo, Huifeng Shen, Zhenping Li, Julian Solway, Enxiang Tao, Y. Jeffrey Chiang, Stanley Lipkowitz, Josef M. Penninger, Wallace Y. Langdon, Jian Zhang
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 709-723 (2014)
E3 ubiquitin ligase Cbl-b has emerged as a gatekeeper that controls the activation threshold of the T cell antigen receptor and maintains the balance between tolerance and autoimmunity. Here, we report that the loss of Cbl-b facilitates T helper 2 (T
Externí odkaz:
https://doaj.org/article/47d1fa5e69ba4bec879466f4c8fe9c8f
Autor:
Hui Guo, Guilin Qiao, Haiyan Ying, Zhenping Li, Yixia Zhao, Yanran Liang, Lifen Yang, Stanley Lipkowitz, Josef M. Penninger, Wallace Y. Langdon, Jian Zhang
Publikováno v:
Cell Reports, Vol 1, Iss 5, Pp 472-482 (2012)
E3 ubiquitin ligase Cbl-b plays a crucial role in T cell activation and tolerance induction. However, the molecular mechanism by which Cbl-b inhibits T cell activation remains unclear. Here, we report that Cbl-b does not inhibit PI3K but rather suppr
Externí odkaz:
https://doaj.org/article/16a2de138b5249439783100580902abf
Publikováno v:
Waike lilun yu shijian, Vol 25, Iss 06, Pp 503-506 (2020)
Objective To explore the feasibility of robotic assisted male thyroidectomy. Methods The data of 228 patients with robotic assisted thyroidectomy in our hospital from May 2015 to September 2017 were analyzed retrospectively. The data of tumor size, o
Externí odkaz:
https://doaj.org/article/2081150187f34f27bf56997a533238aa
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::453c4a4f4a355bbb2f9536523305c149
https://doi.org/10.1136/jitc-2022-sitc2022.0905
https://doi.org/10.1136/jitc-2022-sitc2022.0905
Autor:
Haibing Deng, Wenqun Xin, Weiling Pan, Zhixuan Zhu, Mei Ning, Hongping Yu, Zhui Chen, Haiyan Ying
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c81ef8ac68e4692fa8d62cdae9ccdf0b
https://doi.org/10.1136/jitc-2022-sitc2022.1441
https://doi.org/10.1136/jitc-2022-sitc2022.1441
Publikováno v:
Cancer Research. 83:LB317-LB317
Introduction: FGFRs play important roles in cancer development and inhibition of FGFR could disrupt tumor cell proliferation and growth. Four selective FGFR inhibitors have been approved (erdafitinib, pemigatinib, infigratinib, and futibatinib) and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961d6a25d72a836e832b70a4b09dfb51
https://doi.org/10.1158/1538-7445.am2023-lb317
https://doi.org/10.1158/1538-7445.am2023-lb317
Publikováno v:
Cancer Research. 83:LB316-LB316
Background: KRAS is frequently mutated in human cancers, including pancreatic (~90%), colorectal (~35%), and lung cancer (~25%). The KRASG12C mutation (single amino acid substitution of cysteine for glycine at position 12) accounts for ~14% of lung c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c87804858e53853a1947ce17c57bb2b3
https://doi.org/10.1158/1538-7445.am2023-lb316
https://doi.org/10.1158/1538-7445.am2023-lb316
Autor:
Haiyan Ying, Nannan Zhang, Haibing Deng, Fei Yang, Wenqun Xin, Bin Shen, Hongping Yu, Zhui Chen, Yao-chang Xu
Publikováno v:
Cancer Research. 83:LB328-LB328
Introduction: Aberrant activation of FGF19-FGFR4 signaling pathway plays an essential role in the tumorigenesis of Hepatocellular carcinoma (HCC) and FGFR4 inhibitors have shown preliminary efficacy in recent clinical trials for patients with FGF19 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693a870224a1c323c1912ddf4446b5a3
https://doi.org/10.1158/1538-7445.am2023-lb328
https://doi.org/10.1158/1538-7445.am2023-lb328
Publikováno v:
Cancer Research. 82:LB530-LB530
Immunotherapy has revolutionized cancer treatment in the last decade. Several monoclonal PD-1 and PD-L1 antibodies have been approved for various cancers. Unlike antibodies, small molecule inhibitors may offer potential advantages in oral dosing, adj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5693dcc40985b39cf6fb0fd9c1135c97
https://doi.org/10.1158/1538-7445.am2022-lb530
https://doi.org/10.1158/1538-7445.am2022-lb530
Development of Practical Teaching Model Based on Intelligent Comprehensive Nursing Practice Platform
Publikováno v:
Studies in health technology and informatics. 250
To solve the problems existing in the traditional nursing practice teaching and enhance the training quality of nursing baccalaureate students. This article developed a nursing practice teaching model based on the intelligent information platform by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23b88430733b5e116273c2eee2e05ca3
https://pubmed.ncbi.nlm.nih.gov/29857450
https://pubmed.ncbi.nlm.nih.gov/29857450