Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Haiwei Mo"'
Autor:
Caiyun Xiong, Haiwei Mo, Jingsheng Fan, Wenchuang Ren, Hu Pei, Yahui Zhang, Ziwei Ma, Wenyi Wang, Jun Huang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10236 (2022)
Southern corn leaf blight is one of the most widespread foliar diseases in maize-producing areas worldwide and can seriously reduce the yield and quality of sweet corn. However, the molecular mechanisms underlying the disease in sweet corn have not b
Externí odkaz:
https://doaj.org/article/9dea9d2b89be4ed58b1ff0d50193086e
Autor:
Lingling Ou, Shujing Liu, Huaishan Wang, Yeye Guo, Lei Guan, Longbin Shen, Ruhui Luo, David E. Elder, Alexander C. Huang, Giorgos Karakousis, John Miura, Tara Mitchell, Lynn Schuchter, Ravi Amaravadi, Ahron Flowers, Haiwei Mou, Fan Yi, Wei Guo, Jina Ko, Qing Chen, Bin Tian, Meenhard Herlyn, Xiaowei Xu
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104614- (2023)
Summary: Background: Only a minority of melanoma patients experience durable responses to immunotherapies due to inter- and intra-tumoral heterogeneity in melanoma. As a result, there is a pressing need for suitable preclinical models to investigate
Externí odkaz:
https://doaj.org/article/e049b032323c4b70b0b77e7ee4b07a9e
Autor:
Haiwei Mou, Deniz M. Ozata, Jordan L. Smith, Ankur Sheel, Suet-Yan Kwan, Soren Hough, Alper Kucukural, Zachary Kennedy, Yueying Cao, Wen Xue
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract CRISPR/Cas9 has revolutionized cancer mouse models. Although loss-of-function genetics by CRISPR/Cas9 is well-established, generating gain-of-function alleles in somatic cancer models is still challenging because of the low efficiency of gen
Externí odkaz:
https://doaj.org/article/578de3f1d83f4486ba462701b06c2cc8
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-4 (2018)
Abstract Two new studies refine our understanding of CRISPR-associated exon skipping and redefine its utility in engineering alternative splicing.
Externí odkaz:
https://doaj.org/article/719bdb60aee448978c10b3b6a8c2a943
Autor:
Haiwei Mou, Jordan L. Smith, Lingtao Peng, Hao Yin, Jill Moore, Xiao-Ou Zhang, Chun-Qing Song, Ankur Sheel, Qiongqiong Wu, Deniz M. Ozata, Yingxiang Li, Daniel G. Anderson, Charles P. Emerson, Erik J. Sontheimer, Melissa J. Moore, Zhiping Weng, Wen Xue
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract CRISPR is widely used to disrupt gene function by inducing small insertions and deletions. Here, we show that some single-guide RNAs (sgRNAs) can induce exon skipping or large genomic deletions that delete exons. For example, CRISPR-mediated
Externí odkaz:
https://doaj.org/article/eb5d5328d15c438ebd69f1e862c787e0
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007579 (2018)
Recursive splicing (RS) is an evolutionarily conserved process of removing long introns via multiple steps of splicing. It was first discovered in Drosophila and recently proven to occur also in humans. The detailed mechanism of recursive splicing is
Externí odkaz:
https://doaj.org/article/4a88be1bc5c649a58b4e2a409aad21f4
Autor:
Xinwei Hou, Liang Sun, Zongmeng Li, Haiwei Mou, Zhijie Yu, Huaixing Li, Peizhen Jiang, Danxia Yu, Hongyu Wu, Xingwang Ye, Xu Lin, Yingying Le
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24815 (2011)
BACKGROUND: Cellular and animal studies implicate multiple roles of amylin in regulating insulin action, glucose and lipid metabolisms. However, the role of amylin in obesity related metabolic disorders has not been thoroughly investigated in humans.
Externí odkaz:
https://doaj.org/article/1b50d6ac02f64ca3b5bb0f662a7dc83b