Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Haitao LAN"'
Autor:
Xu Jia, Danting Mao, Jianwei Guo, Jiangyu Ke, Yanlin Zhu, Xiaoyang Zhao, Ziren Luo, Xinghai Liu, Rui Tang, Ruihan Hou, Haitao Lan, Qian zheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Long-term exposure to hyperglycemic conditions leads to β-cell dysfunction, particularly mitochondrial dysfunction, and inflammatory and oxidative stress responses, which are considered the primary causes of β-cell death and the hallmarks
Externí odkaz:
https://doaj.org/article/0a7e093681f9453e8c355ffd13e3da01
Publikováno v:
Molecules, Vol 29, Iss 6, p 1405 (2024)
Design of amyloid β-protein (Aβ) inhibitors is considered an effective strategy for the prevention and treatment of Alzheimer’s disease (AD). However, the limited blood–brain barrier (BBB) penetration and poor Aβ-targeting capability restricts
Externí odkaz:
https://doaj.org/article/fc26827210a84940bb8d7bd5b21caa1a
Autor:
Chuan Xu, Guoxiang Jin, Hong Wu, Wei Cui, Yu-Hui Wang, Rajesh Kumar Manne, Guihua Wang, Weina Zhang, Xian Zhang, Fei Han, Zhen Cai, Bo-Syong Pan, Che-Chia Hsu, Yiqiang Liu, Anmei Zhang, Jie Long, Hongbo Zou, Shuang Wang, Xiaodan Ma, Jinling Duan, Bin Wang, Weihui Liu, Haitao Lan, Qing Xiong, Gang Xue, Zhongzhu Chen, Zhigang Xu, Mark E. Furth, Sarah Haigh Molina, Yong Lu, Dan Xie, Xiu-Wu Bian, Hui-Kuan Lin
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Cancer stem-like cells (CSLCs) acquire enhanced immune checkpoint responses to evade immune cell killing and promote tumor progression. Here we showed that signal regulatory protein γ (SIRPγ) determined CSLC properties and immune evasiveness in a s
Externí odkaz:
https://doaj.org/article/ed9d232ee19b4520b69e25795aaa76fb
Publikováno v:
PeerJ, Vol 9, p e11377 (2021)
Background Breast cancer (BC), one of the most widespread cancers worldwide, caused the deaths of more than 600,000 women in 2018, accounting for about 15% of all cancer-associated deaths in women that year. In this study, we aimed to discover potent
Externí odkaz:
https://doaj.org/article/a316ecf19aa44d4eb39262336fbaa473
Publikováno v:
Chinese Journal of Lung Cancer, Vol 19, Iss 9, Pp 571-576 (2016)
Background and objective The inhibitory ability of miR-424 on the proliferation of renal carcinoma cell and the migration and invasion of cancer cells has been widely explored and demonstrated. However, the effects of miR-424 on non-small cell lung c
Externí odkaz:
https://doaj.org/article/08d79182ccfe4404bb4951a029b97032
Autor:
Guangxi LI, Haitao LAN, Zhiguo LIU, Ting RUI, Jiapeng LU, Lingjie BIAN, Yinghui WANG, Shihan WANG, Hong ZHANG, Yongjun BIAN, Hui LI, Yuyan GUO, Shigang LIU, Liang LI
Publikováno v:
Iranian Journal of Public Health, Vol 46, Iss 11 (2017)
Background: We tried to investigate the effect of PM2.5 on daily counts of outpatient visits in the Guang’anmen Hospital to determine if short-term PM2.5 exposure with extremely high concentration affects cardiopulmonary function of Beijing residen
Externí odkaz:
https://doaj.org/article/9599e248c3bf4a0cb5bd5f487bae4e4a
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42978 (2012)
BACKGROUND: It is controversial whether microRNA-126 is a tumor suppressive or oncogenic miRNA. More experiments are needed to determine whether microRNA-126 is associated with non-small cell lung cancer risk and prognosis. METHODS: Over-expression o
Externí odkaz:
https://doaj.org/article/517c347c74324022ad2c96436ab51969
Due to the complicated influences of the car door system, the closing comfort is difficult to evaluate in the design of the car door system. In order to solve the problem and increase the development efficiency, based on the work of the whole process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::703005160b36c1bdd1f0b5f72ba981bf
https://doi.org/10.21203/rs.3.rs-2948169/v1
https://doi.org/10.21203/rs.3.rs-2948169/v1
Publikováno v:
Journal of Pipeline Systems Engineering and Practice. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d931b830637f26ec945b3056640ea750
https://doi.org/10.1061/jpsea2.pseng-1412
https://doi.org/10.1061/jpsea2.pseng-1412
Publikováno v:
Géotechnique. :1-13
Although the structural response of pipelines has been studied in relation to different geohazards, few studies have focused on the behaviour of flexible pipeline joints. In this paper, the response of a bell-and-spigot joint in a 600 mm dia. lined-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f9f412f8f6722dd89ab6b49c75df89
https://doi.org/10.1680/jgeot.21.00196
https://doi.org/10.1680/jgeot.21.00196