Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Haishun, Ye"'
Publikováno v:
Chemical Communications. 59:1497-1500
A unique coupling of diphenylcyclopropenones and 1,2-aminothiol in water at pH 7.4 produces an amide conjugate with the release of thiol for multiple bioconjugation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::933c85eb98b90bb0f92f64284a38faf5
https://doi.org/10.1039/d2cc06419g
https://doi.org/10.1039/d2cc06419g
Publikováno v:
Chemical Communications. 59:4233-4236
Cysteine esters and amides spontaneously degrade under physiological conditions to generate H2S. This discovery not only provides new insights into fundamental science issues, but also inspires a class of tunable cleavage motifs for prodrug design.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a17321b97b98764c925023b0b946e0
https://doi.org/10.1039/d3cc00684k
https://doi.org/10.1039/d3cc00684k
Publikováno v:
Chemistry – A European Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a609db005ddacb87539606b5b749a40
https://doi.org/10.1002/chem.202301105
https://doi.org/10.1002/chem.202301105
Autor:
Haishun Ye, Lu Sun, Zhili Pang, Xiuru Ji, Yan Jiao, Xiaoqiang Tu, Haojie Huang, Xinjing Tang, Zhen Xi, Long Yi
Publikováno v:
Analytical Chemistry. 94:1733-1741
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd8bcffb5ee41831123b58e62e247d78
https://doi.org/10.1021/acs.analchem.1c04324
https://doi.org/10.1021/acs.analchem.1c04324
Publikováno v:
New Journal of Chemistry. 46:7859-7863
Thiobenzophenones are tunable structural motifs for intracellular H2S delivery through hydrolysis reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de8c17c60089100efdce12d0ec221d9
https://doi.org/10.1039/d2nj01152b
https://doi.org/10.1039/d2nj01152b
Publikováno v:
RSC Chemical Biology. 3:848-852
Using both thiolysis of NBD amine and CBD arylether as dual receptors, we rationally design a dual-quenching probe for the detection of the biogenesis of H2S + GSH derived from l-Cys rather than d-Cys in live cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e580a92ca69ab7b8d5cb007deff19e7f
https://doi.org/10.1039/d2cb00105e
https://doi.org/10.1039/d2cb00105e
Publikováno v:
Journal of Materials Chemistry B.
A highly selective and sensitive, endoplasmic reticulum (ER)-targeted fluorescent probe was successfully developed and applied to reveal HOCl- and cisplatin-induced H2S biogenesis in live cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172d65f34fd671e35c40c3110fea694d
https://doi.org/10.1039/d3tb00863k
https://doi.org/10.1039/d3tb00863k
Publikováno v:
Organic & Biomolecular Chemistry. 19:6527-6533
In order to evaluate 7-sulfonamide benzoxadiazole (SBD) derivatives for the development of fluorescent probes, herein we investigated the thiolysis reactivity and selectivity of a series of SBD compounds with different atoms (N/O/S/Se) at the 4-posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019de40d219c92b6ea9ffddc86d7ff9e
https://doi.org/10.1039/d1ob01114f
https://doi.org/10.1039/d1ob01114f
Publikováno v:
Organicbiomolecular chemistry. 20(20)
The thiolysis of NBD piperazinyl amine (NBD-PZ) is highly selective for H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b8b001501e545cbd267d1d8f94901d4
https://pubmed.ncbi.nlm.nih.gov/35510487
https://pubmed.ncbi.nlm.nih.gov/35510487
Autor:
Zhen Xi, Haojie Huang, Sarah G. Bolton, Xueying Kang, Ismail Ismail, Zhuoyue Chen, Michael D. Pluth, Haibin Song, Xiuru Ji, Lu Sun, Long Yi, Haishun Ye
Publikováno v:
Chemical Science
H2S is a well-known toxic gas and also a gaseous signaling molecule involved in many biological processes. Advanced chemical tools that can regulate H2S levels in vivo are useful for understanding H2S biology as well as its potential therapeutic effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4318d35e8bd019509e28e03f104f80
http://europepmc.org/articles/PMC8163142
http://europepmc.org/articles/PMC8163142