Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hairat Sabit"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 89-96 (2013)
The fluorophosphonate (FP) moiety attached to a biotin tag is a prototype chemical probe used to quantitatively analyze and enrich active serine hydrolases in complex proteomes in an approach called activity-based protein profiling (ABPP). In this st
Externí odkaz:
https://doaj.org/article/9a93aadf018146cd862bf26057f9bec3
Autor:
Gordon L. Amidon, Kefeng Sun, Kyung Dall Lee, Hao Xu, Chester J. Provoda, Hairat Sabit, John L. Hilfinger
Publikováno v:
Molecular Pharmaceutics. 15:410-419
The prodrug strategy has been frequently employed as a chemical approach for overcoming the disadvantages of existing parent drugs. In this report, we synthesized four monoester prodrugs of ganciclovir, an anticytomegalovirus drug, and demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376b2dbc0e5becba89c42b3ede117f9f
https://doi.org/10.1021/acs.molpharmaceut.7b00792
https://doi.org/10.1021/acs.molpharmaceut.7b00792
Publikováno v:
Journal of Biological Chemistry. 288:32394-32404
Human apical sodium-dependent bile acid transporter (hASBT, SLC10A2) is responsible for intestinal reabsorption of bile acids and plays a key role in cholesterol homeostasis. We used a targeted and systematic approach to delineate the role of highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893b938beefc26c796dd41cac78fe6a2
https://doi.org/10.1074/jbc.m113.518555
https://doi.org/10.1074/jbc.m113.518555
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 89-96 (2013)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The fluorophosphonate (FP) moiety attached to a biotin tag is a prototype chemical probe used to quantitatively analyze and enrich active serine hydrolases in complex proteomes in an approach called activity-based protein profiling (ABPP). In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05c8edb1e63f7ddbe829d2817080144
https://doaj.org/article/9a93aadf018146cd862bf26057f9bec3
https://doaj.org/article/9a93aadf018146cd862bf26057f9bec3
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 37(10)
The purpose of this study was to thoroughly characterize the efflux transporters involved in the intestinal permeability of the oral microtubule polymerization inhibitor colchicine and to evaluate the role of these transporters in limiting its oral a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c5dd4a4720082972ce684bab22a180
https://pubmed.ncbi.nlm.nih.gov/19589874
https://pubmed.ncbi.nlm.nih.gov/19589874
Publikováno v:
The AAPS journal. 11(2)
The aim of this study was to elucidate the intestinal epithelial cell efflux transport processes that are involved in the intestinal transport of the H(2) receptor antagonist nizatidine. The intestinal epithelial efflux transport mechanisms of nizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8edae239c62f91a8d441854c55b4cb2
https://pubmed.ncbi.nlm.nih.gov/19319690
https://pubmed.ncbi.nlm.nih.gov/19319690