Výsledky vyhledávání - "Haiqun(John) Jia"

Abstract 4259: PT199, a next generation anti-CD73 mAb that inhibits both membrane-bound and soluble CD73 activity to completion without 'hook effect'

Autor: Haiqun (John) Jia, Jack Li, Fen Pei, Lorraine Greenwood, Lauren Pejza, Yan Long, Kelan Chen, Jessica Perer, Ming Wang, Hui Zou

Publikováno v: Cancer Research. 82:4259-4259

CD73, also known as ecto-5’-nucleotidase, is implicated in promoting immunosuppressive tumor microenvironment (TME) through production of adenosine. The first generation of anti-CD73 therapeutic antibodies currently in clinical studies have largely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a0589dca6757164ab9a7dcfe8f9fc9e
https://doi.org/10.1158/1538-7445.am2022-4259

Zobrazit plný text záznamu

Abstract 2908: PT217, an anti-DLL3/anti-CD47 bispecific antibody, exhibits anti-tumor activity through novel mechanisms of action

Autor: Haiqun(John) Jia, Dorthy Fang, Molly Lobsinger, Yan Long, Kelan Chen, Albert Lam, Yangyang Guo, Kaisa Selesniemi, Ming Wang, Hui Zou

Publikováno v: Cancer Research. 82:2908-2908

Small cell lung cancer (SCLC) is the most lethal subtype of lung cancers with few patients surviving more than 5 years from diagnosis. While SCLC initially responds well to standard chemotherapy treatment, chemotherapy-resistant recurrence is charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bead8580f747a0f4e0f9182fb0e2503
https://doi.org/10.1158/1538-7445.am2022-2908

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání