Screening of deafness-causing DNA variants that are common in patients of European ancestry using a microarray-based approach.

Autor: Denise Yan, Guangxin Xiang, Xingping Chai, Jie Qing, Haiqiong Shang, Bing Zou, Rahul Mittal, Jun Shen, Richard J H Smith, Yao-Shan Fan, Susan H Blanton, Mustafa Tekin, Cynthia Morton, Wanli Xing, Jing Cheng, Xue Zhong Liu

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0169219 (2017)

The unparalleled heterogeneity in genetic causes of hearing loss along with remarkable differences in prevalence of causative variants among ethnic groups makes single gene tests technically inefficient. Although hundreds of genes have been reported

Externí odkaz: https://doaj.org/article/b3e763a4b1d042b89edcf775468cd572

The expression of PHB2 in the cochlea: Possible relation to age-related hearing loss

Autor: Zhiqi Ma, Haiqiong Shang, Yueqiu Gao, Xiaoyu Yu, Yong Li, Ming Guan, Yaoshu Teng, Xiaolin Cao, Bin Wang

Publikováno v: Cell biology internationalREFERENCES. 45(12)

Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly, but its mechanism remains unclear. Scaffold protein Prohibitin 2 (PHB2) has been widely involved in aging and neurodegeneration. However, the role of PHB2 in ARHL i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a82208f509df35df6569ba9c4136bf3
https://pubmed.ncbi.nlm.nih.gov/34435719

Facilitation of facial nerve regeneration using chitosan-β-glycerophosphate-nerve growth factor hydrogel

Autor: Lei Xu, Haibo Wang, Xiaofei Li, Yanyan Mao, Zhaomin Fan, Yuechen Han, Haiqiong Shang, Xiuhua Chao, Jianfeng Li

Publikováno v: Acta Oto-Laryngologica. 136:585-591

Conclusion C/GP hydrogel was demonstrated to be an ideal drug delivery vehicle and scaffold in the vein conduit. Combined use autologous vein and NGF continuously delivered by C/GP-NGF hydrogel can improve the recovery of facial nerve defects. Object

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ed4005cf42fc5f35d9a073d5c51faf
https://doi.org/10.3109/00016489.2015.1136432

Artemin transiently increases iNOS expression in primary cultured trigeminal ganglion neurons

Autor: Gaoying Sun, Yuechen Han, Zhaomin Fan, Xiaohui Bai, Jianfeng Li, Xiuhua Chao, Haibo Wang, Haiqiong Shang, Lei Xu, Yan Wang

Publikováno v: Neuroscience letters. 660

Artemin, a member of the glial cell line-derived neurotrophic factor family, is an important cytokine and a critical participant in trigeminal pain disorders such as tongue pain and migraine. However, the mechanisms underlying artemin's activity are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715d8a2bcadb4c505a1fbf1ce327570d
https://pubmed.ncbi.nlm.nih.gov/28899786

Screening of deafness-causing DNA variants that are common in patients of European ancestry using a microarray-based approach

Autor: Susan H. Blanton, Richard J.H. Smith, Wanli Xing, Rahul Mittal, Xingping Chai, Xue Zhong Liu, Denise Yan, Yao Shan Fan, Guangxin Xiang, Mustafa Tekin, Haiqiong Shang, Jing Cheng, Bing Zou, Jie Qing, Cynthia C. Morton, Jun Shen

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0169219 (2017)
PLoS ONE
Yan, D, Xiang, G, Chai, X, Qing, J, Shang, H, Mittal, B Z R, Shen, J, Smith, R J H, Fan, Y S, Blanton, S H, Tekin, M, Morton, C, Xing, W, Cheng, J & Liu, X Z 2017, ' Screening of deafness-causing DNA variants that are common in patients of European ancestry using a microarray-based approach ', PLoS ONE, vol. 12, no. 3, e0169219 . https://doi.org/10.1371/journal.pone.0169219

The unparalleled heterogeneity in genetic causes of hearing loss along with remarkable differences in prevalence of causative variants among ethnic groups makes single gene tests technically inefficient. Although hundreds of genes have been reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d3ca8cbaa488847287e88f0c813ffe
https://doi.org/10.1371/journal.pone.0169219