Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Haipeng Tao"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e20de65d6ade44daa50439512a26e6e7
Autor:
Linchun Jin, Haipeng Tao, Aida Karachi, Yu Long, Alicia Y. Hou, Meng Na, Kyle A. Dyson, Adam J. Grippin, Loic P. Deleyrolle, Wang Zhang, Didier A. Rajon, Qiong J. Wang, James C. Yang, Jesse L. Kresak, Elias J. Sayour, Maryam Rahman, Frank J. Bova, Zhiguo Lin, Duane A. Mitchell, Jianping Huang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
CAR T-cell therapy efficacy in solid tumors is limited by inadequate T-cell migration and/or persistence in tumour microenvironment. Here, the authors show that the activity of tumour-antigen specific CAR T cells, in multiple preclinical mouse models
Externí odkaz:
https://doaj.org/article/de9a908e5e6e46b0b45bc79a9225470e
Autor:
Duy T. Nguyen, Elizabeth Ogando-Rivas, Ruixuan Liu, Theodore Wang, Jacob Rubin, Linchun Jin, Haipeng Tao, William W. Sawyer, Hector R. Mendez-Gomez, Matthew Cascio, Duane A. Mitchell, Jianping Huang, W. Gregory Sawyer, Elias J. Sayour, Paul Castillo
Publikováno v:
Cells, Vol 11, Iss 12, p 1974 (2022)
The promising outcomes of chimeric antigen receptor (CAR) T cell therapy in hematologic malignancies potentiates its capability in the fight against many cancers. Nevertheless, this immunotherapy modality needs significant improvements for the treatm
Externí odkaz:
https://doaj.org/article/7ccd12e916a543e9999556664a8c4baa
Autor:
Luyan Mu, Yu Long, Changlin Yang, Linchun Jin, Haipeng Tao, Haitao Ge, Yifan E. Chang, Aida Karachi, Paul S. Kubilis, Gabriel De Leon, Jiping Qi, Elias J. Sayour, Duane A. Mitchell, Zhiguo Lin, Jianping Huang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Background: Malignant gliomas are heterogeneous brain tumors with the potential for aggressive disease progression, as influenced by suppressive immunoediting. Given the success and enhanced potential of immune-checkpoint inhibitors in immunotherapy,
Externí odkaz:
https://doaj.org/article/7c5ff51734664520ae68a2503eea7c4d
Autor:
Jianping Huang, Zhiguo Lin, Duane A. Mitchell, Maryam Rahman, Elias J. Sayour, Loic P. Deleyrolle, Meng Na, Alicia Y. Hou, Kyle A. Dyson, Wang Zhang, Yifan (Emily) Chang, Linchun Jin, Adam J. Grippin, Aida Karachi, Haipeng Tao, Yu Long
Suppl Materials and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79be2330f5a4ad098d373bf7e399a90
https://doi.org/10.1158/0008-5472.22425468.v1
https://doi.org/10.1158/0008-5472.22425468.v1
Autor:
Jianping Huang, Zhiguo Lin, Duane A. Mitchell, Maryam Rahman, Elias J. Sayour, Loic P. Deleyrolle, Meng Na, Alicia Y. Hou, Kyle A. Dyson, Wang Zhang, Yifan (Emily) Chang, Linchun Jin, Adam J. Grippin, Aida Karachi, Haipeng Tao, Yu Long
Anti-VEGF therapy prolongs recurrence-free survival in patients with glioblastoma but does not improve overall survival. To address this discrepancy, we investigated immunologic resistance mechanisms to anti-VEGF therapy in glioma models. A screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbb9786863c241eb9642f73b936fdda
https://doi.org/10.1158/0008-5472.c.6512046
https://doi.org/10.1158/0008-5472.c.6512046
Autor:
Alicia Y Hou, Wang Zhang, Kyle Dyson, Elias Sayour, Loic P. Deleyrolle, Jianping Huang, Duane Mitchell, Yu Long, Linchun Jin, Zhiguo Lin, Meng Na, Aida Karachi, Yifan Emily Chang, Adam Grippin, Maryam Rahman, Haipeng Tao
Publikováno v:
Cancer Research. 80:499-509
Anti-VEGF therapy prolongs recurrence-free survival in patients with glioblastoma but does not improve overall survival. To address this discrepancy, we investigated immunologic resistance mechanisms to anti-VEGF therapy in glioma models. A screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210839f0e7c48b6f7b7d7b019af2de26
https://doi.org/10.1158/0008-5472.can-19-1577
https://doi.org/10.1158/0008-5472.can-19-1577
Autor:
Aida Karachi, Maryam Rahman, Linchun Jin, Haipeng Tao, Farhad Dastmalchi, Duane Mitchell, Jianping Huang
Publikováno v:
Neuro Oncol
CD70 CAR T cells developed by our group have anti-tumor efficacy in syngeneic murine GBM model and are currently being developed for first-in-human testing. The objective of this study was to evaluate the impact of temozolomide (TMZ) in various dosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db9e6393841c090d228de4f4894dc68
https://europepmc.org/articles/PMC8598671/
https://europepmc.org/articles/PMC8598671/
Autor:
Haipeng Tao, Dongjiang Chen, Changlin Yang, Linchun Jin, Christina Von Roemeling, Hector Mendez-Gomez, Ruixuan Liu, Duy Nguyen, Alicia Y Hou, Alfonso Pepe, Frances Weidert, Ashley Ghiaseddin, Duane Mitchell, Loic Deleyrolle, Elias Sayour, W Sawyer, David Tran, Jianping Huang
Publikováno v:
Neuro-Oncology. 24:vii222-vii222
BACKGROUND In recent years, emerging evidence indicates that tumor-associated myeloid cells (TAMCs) affect cancer progression. But the molecular mechanisms and signaling pathways involved in the TAMCs’ interaction with extracellular matrix (ECM) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b50d54deb675bee1757ada29e5331b0
https://doi.org/10.1093/neuonc/noac209.855
https://doi.org/10.1093/neuonc/noac209.855
Autor:
Frank J. Bova, Jesse Kresak, Linchun Jin, Adam Grippin, Qiong J. Wang, Yu Long, Jianping Huang, Alicia Y Hou, Meng Na, Aida Karachi, James Chih-Hsin Yang, Didier A. Rajon, Maryam Rahman, Loic P. Deleyrolle, Elias Sayour, Duane Mitchell, Haipeng Tao, Wang Zhang, Zhiguo Lin, Kyle Dyson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Chimeric antigen receptor (CAR) T-cell therapy targeting solid tumors has stagnated as a result of tumor heterogeneity, immunosuppressive microenvironments, and inadequate intratumoral T cell trafficking and persistence. Early (≤3 days) intratumora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb4f8a686f29405567b1fda2109954a
https://doaj.org/article/de9a908e5e6e46b0b45bc79a9225470e
https://doaj.org/article/de9a908e5e6e46b0b45bc79a9225470e