Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Haini N. Cai"'
Publikováno v:
Developmental Biology. 476:189-199
The three-dimensional (3D) organization of the genome is highly dynamic, changing during development and varying across different tissues and cell types. Recent studies indicate that these changes alter regulatory interactions, leading to changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964f0d98494df38a732e2c111b4a8716
https://doi.org/10.1016/j.ydbio.2021.03.022
https://doi.org/10.1016/j.ydbio.2021.03.022
Autor:
Sapna K. Patel, Ping Shen, Mo Li, Matthew L. Romine, Haini N. Cai, Julie G. Nelson, Kevin Jiayang Liu
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Cell density regulates many aspects of cell properties and behaviors including metabolism, growth, cytoskeletal structure and locomotion. Importantly, the responses by cultured cells to density signals also uncover key mechanisms that govern animal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39890bb45f5c5ed8843e0e7405917ab7
http://link.springer.com/article/10.1038/s41598-019-47652-0
http://link.springer.com/article/10.1038/s41598-019-47652-0
Pairing of food aroma with selected taste can lead to enhanced food flavor and eating euphoria, but how cross-modal sensory combinations are integrated to increase food reward value remains largely unclear. Here we report that combined stimulation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98023363b1a07b0f4fec733e453a89d6
https://doi.org/10.1101/859223
https://doi.org/10.1101/859223
Autor:
Mo Fong Li, Haini N. Cai, Derrick C. Lane, Zhibo Ma, Carly R. Duffy, Sapna K. Patel, Sharmila Roy
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
The three-dimensional organization of the eukaryotic genome is important for its structure and function. Recent studies indicate that hierarchies of chromatin loops underlie important aspects of both genomic organization and gene regulation. Looping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b649cdb18aa96e2db8a4a14fc365db3e
https://doi.org/10.1038/s41598-018-33588-4
https://doi.org/10.1038/s41598-018-33588-4
Publikováno v:
Behavioural Brain Research. 278:506-513
Our previous studies have demonstrated a critical role of a VEGFR-like signaling pathway in hunger-driven overeating of sugar-rich food in Drosophila larvae. In the current study, we investigate whether the VEGFR signaling mechanism plays a similar r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c466f7c0443a7332dafde04e856ddcde
https://doi.org/10.1016/j.bbr.2014.10.004
https://doi.org/10.1016/j.bbr.2014.10.004
Autor:
Zhibo Ma, Mo Li, Sharmila Roy, Derrick C. Lane, Haini N. Cai, Matthew L. Romine, Kevin Jiayang Liu, Sapna K. Patel
The three-dimensional (3D) organization of the eukaryotic genome is critical for its proper function. Evidence suggests that extensive chromatin loops form the building blocks of the genomic architecture, separating genes and gene clusters into disti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed857634a9cdd5f45ec8d2b6b3e21e86
https://europepmc.org/articles/PMC4997523/
https://europepmc.org/articles/PMC4997523/
Autor:
Sharmila Roy, Dimple R. Bosu, Meena Puppali, Haini N. Cai, Parimal Majumder, Vladimir E. Belozerov
Publikováno v:
Nucleic Acids Research
Chromatin boundaries regulate gene expression by modulating enhancer–promoter interactions and insulating transcriptional influences from organized chromatin. However, mechanistic distinctions between these two aspects of boundary function are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd495b6fcbdeb2abc97fd2f1df0e8c06
https://doi.org/10.1093/nar/gkp362
https://doi.org/10.1093/nar/gkp362
Chromatin boundary elements (CBEs) are widely distributed in the genome and mediate formation of chromatin loops, but their roles in gene regulation remain poorly understood. The complex expression pattern of the Drosophila homeotic gene Sex combs re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faaf55a5328af29a3433faf2580e5fe4
https://europepmc.org/articles/PMC4628056/
https://europepmc.org/articles/PMC4628056/
Autor:
Haini N. Cai, Parimal Majumder
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5223-5228
Chromatin boundaries or insulators modulate enhancer–promoter interactions in complex genetic loci. However, the mechanism underlying insulator activity is not known. Previous studies showed that the activity of the Drosophila suHw insulator is abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49466614490a86ceddbc836672684ba
https://doi.org/10.1073/pnas.0830190100
https://doi.org/10.1073/pnas.0830190100
Autor:
Ping Shen, Haini N. Cai
Publikováno v:
Journal of Neurobiology. 47:16-25
The conserved neuropeptide Y (NPY) signaling pathway has been strongly implicated in the stimulation of food uptake in vertebrates as well as in the regulation of food conditioned foraging behaviors of Caenorhabditis elegans. Using in situ RNA hybrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa33cafe3cd1c35f6493f857319bcefb
https://doi.org/10.1002/neu.1012
https://doi.org/10.1002/neu.1012