Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Haing Da Nguyen"'
Autor:
Charles Boone, Haing Da Nguyen, Anja Katrin Bielinsky, Michael Costanzo, Elizabeth N. Koch, Jordan R. Becker, Yee Mon Thu, Kyungjae Myung, Stephanie Smith, Chad L. Myers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e66379 (2013)
PLoS ONE, Vol 8, Iss 6, p e66379 (2013)
Deficiency in DNA ligase I, encoded by CDC9 in budding yeast, leads to the accumulation of unligated Okazaki fragments and triggers PCNA ubiquitination at a non-canonical lysine residue. This signal is crucial to activate the S phase checkpoint, whic