CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages

Autor: Mohamed, Sally H., Vanhoffelen, Eliane, Shun Fu, Man, Hei Lau, Pui, Hain, Sofia, Seldeslachts, Laura, Cosway, Emilie, Anderson, Graham, McCulloch, Laura, Vande Velde, Greetje, Drummond, Rebecca A.

Publikováno v: In Mucosal Immunology December 2024 17(6):1256-1272

CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhiinterstitial lung macrophages

Autor: Mohamed, Sally H., Vanhoffelen, Eliane, Shun Fu, Man, Hei Lau, Pui, Hain, Sofia, Seldeslachts, Laura, Cosway, Emilie, Anderson, Graham, McCulloch, Laura, Vande Velde, Greetje, Drummond, Rebecca A.

Publikováno v: Mucosal immunology; December 2024, Vol. 17 Issue: 6 p1256-1272, 17p

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The glucocorticoid dexamethasone inhibits HIF-1α stabilization and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages.

Autor: Clayton SA; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK., Lockwood C; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., O'Neil JD; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Daley KK; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Hain S; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Abdelmottaleb D; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; Zoology Department, Faculty of Science, Benha University, Benha, Egypt., Bolimowska OO; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Tennant DA; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK., Clark AR; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.

Publikováno v: Discovery immunology [Discov Immunol] 2023 Dec 04; Vol. 2 (1), pp. kyad027. Date of Electronic Publication: 2023 Dec 04 (Print Publication: 2023).