Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Haimeng Tang"'
Comprehensive profiling of pathogenic germline large genomic rearrangements in a pan‐cancer analysis
Autor:
Zhe Sun, Chujie Bai, Miaoyi Su, Haimeng Tang, Xiaoying Wu, Yue Wang, Hua Bao, Xunbiao Liu, Xue Wu, Yang Shao, Bei Xu
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1917-1929 (2023)
The presence of large genomic rearrangements (LGRs) has been heavily investigated in breast and ovarian cancer. However, correlations between LGRs and cancer types beyond these two have not been extensively profiled, likely due to the highly ineffici
Externí odkaz:
https://doaj.org/article/eaf06227f43a4ee4beb07025d445b08b
Autor:
Ruoying Yu, Hua Bao, Rui Liu, Haimeng Tang, Yong Wu, Liuqing Zhu, Kaihua Liu, Sisi Liu, Xue Wu, Yang Shao
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101622- (2024)
Externí odkaz:
https://doaj.org/article/b8f19755dca14934a3b83852322bd4b1
Autor:
Qi Xu, Xiaoqing Xu, Haimeng Tang, Junrong Yan, Jingjing Li, Hua Bao, Xue Wu, Yang Shao, Cong Luo, Haimin Wen, Jianying Jin, Jieer Ying
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-11 (2023)
Abstract HER2-positive gastric cancer (GC) makes up 15–20% of all GC incidences, and targeted therapy with trastuzumab is the standard of treatment. However, the mechanisms of resistance to trastuzumab are still not fully understood and presents a
Externí odkaz:
https://doaj.org/article/211540b0891f454994f2b4c2afd6bc6d
Publikováno v:
Cancer Research. 83:6079-6079
Background: FBXW7 is a critical tumor suppressor gene of human colorectal cancers (CRC). However, the comprehensive profiling of FBXW7 in CRC is largely underrepresented in current studies. Herein, we present molecular profiling of FBXW7 in human CRC
Publikováno v:
Cancer Research. 83:939-939
Background: Primary mediastinal large B-cell lymphoma (PMBCL), arising from thymic medullary B cells, shares molecular features with classic Hodgkin lymphoma (cHL), including activation of JAK/STAT and Nuclear Factor Kappa B (NF-ƙB) pathways, as wel
Autor:
Fei Liu, Kaoqing Peng, Rui Chen, Mingzhao Li, Tao Zeng, Yan Zhao, Ming Wang, Hongxing Liu, Jianhao Wu, Min Wu, Haimeng Tang, Hua Bao, Xue Wu, Yang Shao, Di Gu, Shancheng Ren
Publikováno v:
Cancer Research. 83:6599-6599
Prostate cancer is one of the most common types of cancer in men. Current prostate-specific antigen (PSA)-based diagnostic strategy for prostate cancer may frequently cause overdiagnosis. In this study, we prospectively recruited 380 individuals, inc
Autor:
Li Li, Kewen He, Aijie Li, Yang Xu, Jiaohui Pang, Dianbin Mu, Jie Ma, Hong Ge, Aurian Maleki, Xueting Qin, Xian Zhang, Qiuxiang Ou, HaiMeng Tang, Yang Shao, Jinming Yu, Shuanghu Yuan
Publikováno v:
Cancer Research. 83:3309-3309
Background: Locally advanced rectal cancers (LARC) are treated with neoadjuvant chemoradiotherapy (nCRT), total mesorectal excision (TME), and adjuvant chemotherapy, and identifying reliable prognostic/predictive biomarkers is currently warranted for
Publikováno v:
Cancer Research. 83:940-940
Background: MET exon 14 skipping mutation (METΔex14) is a key driver event in non-small cell lung cancer (NSCLC), and can be acquired following drug resistance to MET, EGFR or ALK inhibitors. Clinical and genomic features of METΔex14 in NSCLC remai
Publikováno v:
Cancer Research. 83:2612-2612
Background: The search for prognostic biomarkers indicating sensitivity to immunotherapy in lung adenocarcinoma patients have zeroed in on genes in the SWI/SNF pathway. However, the mutational profiles of the relevant key genes on this pathway have n
Autor:
Rong Huang, Gaigai Shen, Yu Ren, Kelin Zheng, Jiayu Wang, Yan Shi, Jiani C. Yin, Lanqun Qin, Guiying Zhang, Mengke Zhao, Xinyu Su, Luqiao Li, Fufeng Wang, Haimeng Tang, Yang Shao, Baorui Liu, Zhengyun Zou
Publikováno v:
Cancer Research. 83:1358-1358
Purpose: Acral melanoma (AM) is the most common subtype in Chinese melanoma patients with a very poor prognosis. However, our understanding of the disease pathogenesis and molecular landscape is limited by the few studies that have been conducted. He