Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Haim Belinson"'
Autor:
Maggie L Chow, Tiziano Pramparo, Mary E Winn, Cynthia Carter Barnes, Hai-Ri Li, Lauren Weiss, Jian-Bing Fan, Sarah Murray, Craig April, Haim Belinson, Xiang-Dong Fu, Anthony Wynshaw-Boris, Nicholas J Schork, Eric Courchesne
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002592 (2012)
Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression
Externí odkaz:
https://doaj.org/article/271731ca984f4c7eb0af7943a32f5218
Autor:
Lia Zepa, Moran Frenkel, Haim Belinson, Zehavit Kariv-Inbal, Rakez Kayed, Eliezer Masliah, Daniel M. Michaelson
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Activating the amyloid cascade by inhibiting the Aβ-degrading enzyme neprilysin in targeted replacement mice, which express either apoE4 or apoE3, results in the specific accumulation of oligomerized Aβ42 in hippocampal CA1 neurons of the apoE4 mic
Externí odkaz:
https://doaj.org/article/cb1bfef81d92434aa6dfa693133c056b
Autor:
Marta Garcia-Miralles, Michael R. Hayden, Mahmoud A. Pouladi, Liang Juin Tan, Jing Ying Tan, Carola I. Radulescu, Neta Zach, Haim Belinson, Harwin Sidik, Nur Amirah Binte Mohammad Yusof
Publikováno v:
Molecular Neurobiology. 56:4464-4478
Laquinimod, an immunomodulatory agent under clinical development for Huntington disease (HD), has recently been shown to confer behavioural improvements that are coupled with prevention of atrophy of the white matter (WM)-rich corpus callosum (CC) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841f37d1e4b6994a413723ba0fdd2992
https://doi.org/10.1007/s12035-018-1393-1
https://doi.org/10.1007/s12035-018-1393-1
Autor:
Karen Pierce, Kristen J. Brennand, Anthony Wynshaw-Boris, Cynthia Carter Barnes, Chen Fu, Yuan Tian, Ana P.D. Mendes, Patricia Cristina Baleeiro Beltrão-Braga, Haim Belinson, Krishna C. Vadodaria, Daniel H. Geschwind, Yanelli Nunez, Eric Courchesne, Jing Ou, Himanish Ghosh, Cleber A. Trujillo, Lisa T. Eyler, Maria C. Marchetto, Tiziano Pramparo, Rebecca Wright, Lawrence F. Eichenfield, Alysson R. Muotri, Fred H. Gage, Krishnan Padmanabhan, Beatriz C.G. Freitas
Publikováno v:
Molecular psychiatry
Molecular psychiatry, vol 22, iss 6
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Molecular psychiatry, vol 22, iss 6
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Autism spectrum disorders (ASD) are common, complex and heterogeneous neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD pathogenesis have been proposed based on genetic studies, brain pathology and imaging, but a maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1116f268c27442f1a1fde94cb04773a
http://europepmc.org/articles/PMC5215991
http://europepmc.org/articles/PMC5215991
Autor:
Richard M. Locksley, Din L. Lin, Ricardo Valladares, Ophir D. Klein, Adam K. Savage, Susan V. Lynch, Yien-Ming Kuo, Haim Belinson, Douglas Fadrosh, Anthony Wynshaw-Boris, Ysbrand M. Nusse
Publikováno v:
JCI insight, vol 1, iss 10
Homeostasis of the gastrointestinal (GI) tract is controlled by complex interactions between epithelial and immune cells and the resident microbiota. Here, we studied the role of Wnt signaling in GI homeostasis using Disheveled 1 knockout (Dvl1–/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a346e91f2aa74d9d092877b7e38c8c
https://escholarship.org/uc/item/84x3b081
https://escholarship.org/uc/item/84x3b081
Autor:
Haim Belinson, Daniel M. Michaelson
Publikováno v:
Journal of Alzheimer's Disease. 17:469-481
This review focuses on apolipoprotein E4 (apoE4), the most prevalent genetic risk factor of Alzheimer's disease, and on in vivo and in vitro model studies of the mechanisms underlying its pathological phenotype. The review will first center on in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4511dc214d5f07c8675ddc10818b72
https://doi.org/10.3233/jad-2009-1065
https://doi.org/10.3233/jad-2009-1065
Autor:
Daniel M. Michaelson, Haim Belinson
Publikováno v:
Journal of Neural Transmission. 116:1427-1434
Apolipoprotein E4 (ApoE4), the most prevalent genetic risk factor for Alzheimer's disease, is histopathologically associated with increased deposition of amyloid-beta and brain inflammation and with impaired neuronal plasticity and repair. We have re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be074f348248fc629123ac0d5a1b12a
https://doi.org/10.1007/s00702-009-0218-9
https://doi.org/10.1007/s00702-009-0218-9
Publikováno v:
Journal of Neurochemistry. 103:1031-1040
The allele E4 of apolipoprotein E4 (apoE4), which is the most prevalent genetic risk factor of Alzheimer's disease (AD), inhibits synaptogenesis and neurogenesis and stimulates apoptosis in brains of apoE4 transgenic mice that have been exposed to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878643c0b12d3a728f91baeca34fb0ec
https://doi.org/10.1111/j.1471-4159.2007.04810.x
https://doi.org/10.1111/j.1471-4159.2007.04810.x
Autor:
Tiziano Pramparo, Cynthia Carter Barnes, Jian-Bing Fan, Sarah S. Murray, Nicholas J. Schork, Eric Courchesne, Hai Ri Li, Maggie Chow, Xiang-Dong Fu, Anthony Wynshaw-Boris, Haim Belinson, Craig April, Mary E. Winn, Lauren A. Weiss
Publikováno v:
PLoS genetics, vol 8, iss 3
PLoS Genetics
PLoS Genetics, Vol 8, Iss 3, p e1002592 (2012)
Chow, ML; Pramparo, T; Winn, ME; Barnes, CC; Li, HR; Weiss, L; et al.(2012). Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genetics, 8(3). doi: 10.1371/journal.pgen.1002592. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/172879gx
PLoS Genetics
PLoS Genetics, Vol 8, Iss 3, p e1002592 (2012)
Chow, ML; Pramparo, T; Winn, ME; Barnes, CC; Li, HR; Weiss, L; et al.(2012). Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genetics, 8(3). doi: 10.1371/journal.pgen.1002592. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/172879gx
Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56520f7976413fe2b5693110d9cac9ca
https://escholarship.org/uc/item/172879gx
https://escholarship.org/uc/item/172879gx
Autor:
Moran Frenkel, Eliezer Masliah, Haim Belinson, Daniel M. Michaelson, Rakez Kayed, Lia Zepa, Zehavit Kariv-Inbal
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
International Journal of Alzheimer's Disease
International Journal of Alzheimer's Disease
Activating the amyloid cascade by inhibiting the Aβ-degrading enzyme neprilysin in targeted replacement mice, which express either apoE4 or apoE3, results in the specific accumulation of oligomerized Aβ42 in hippocampal CA1 neurons of the apoE4 mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edac6f64c215fdca597a8ac2cfcee28
https://doaj.org/article/cb1bfef81d92434aa6dfa693133c056b
https://doaj.org/article/cb1bfef81d92434aa6dfa693133c056b