Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Haim, Meshulam"'
Autor:
Ginny G. Farías, Juan A. Godoy, Mary C. Vázquez, Rellie Adani, Haim Meshulam, Jesús Avila, Gabi Amitai, Nibaldo C. Inestrosa
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 176-183 (2005)
Changes in signal transduction are implicated in neuronal responses to the Alzheimer's amyloid-β-peptide (Aβ), which include neurotransmitter systems and pathways involved in the maintenance of the nervous system. We report here that a new bifuncti
Externí odkaz:
https://doaj.org/article/db85b3ed207248358c7d637449a36bd5
Publikováno v:
International Immunopharmacology. 7:1129-1139
Experimental autoimmune encephalomyelitis (EAE) is a central nervous system (CNS) inflammatory model in which MOG-specific T-cells initiate an autoimmune attack leading to demyelinization and consequently, neurological damage and morbidity. As EAE pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c09b140d6cd3e375657a85e41743ce
https://doi.org/10.1016/j.intimp.2007.03.009
https://doi.org/10.1016/j.intimp.2007.03.009
Autor:
Shelly Yishay, Leonid Gaidukov, Michal Lindenbaum, Peter Bel, Gabriel Amitai, Guy Yacov, Dan S. Tawfik, Shai Teitlboim, R. Adani, Moshe Kushnir, Haim Meshulam, Olga Khersonsky
Publikováno v:
FEBS Journal. 273:1906-1919
We addressed the ability of various organophosphorus (OP) hydrolases to catalytically scavenge toxic OP nerve agents. Mammalian paraoxonase (PON1) was found to be more active than Pseudomonas diminuta OP hydrolase (OPH) and squid O,O-di-isopropyl flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8c982247a704c961c35033dab122ce8
https://doi.org/10.1111/j.1742-4658.2006.05198.x
https://doi.org/10.1111/j.1742-4658.2006.05198.x
Autor:
Nibaldo C. Inestrosa, Gabi Amitai, Jesús Avila, Ginny G. Farías, R. Adani, Haim Meshulam, Juan A. Godoy, Mary Carmen Vázquez
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 176-183 (2005)
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
instname
Changes in signal transduction are implicated in neuronal responses to the Alzheimer's amyloid-β-peptide (Aβ), which include neurotransmitter systems and pathways involved in the maintenance of the nervous system. We report here that a new bifuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e4757e3c56c461c7e33c749f283b8f
https://doi.org/10.1016/j.nbd.2004.09.012
https://doi.org/10.1016/j.nbd.2004.09.012
Publikováno v:
Journal of Applied Toxicology. 26:81-87
Certain organophosphorus (OP) nerve agents (e.g. soman) induce neuroinflammatory processes during acute poisoning. An increased level of typical inflammation markers was also observed in poisoning by alkylating agents such as sulfur mustard (HD). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6e8e041f63300de785452836f203a1
https://doi.org/10.1002/jat.1111
https://doi.org/10.1002/jat.1111
Autor:
Orli Eisenberg, Yishai Karton, Daniele Marciano, Rachel Haring, Abraham Fisher, Zipora Pittel, Rachel Brandeis, Haim Meshulam, Eliahu Heldman, Nira Bar-Ner, Naomi Eshhar
Publikováno v:
Journal of Physiology-Paris. 92:337-340
M1 selective agonists from the AF series (e.g. AF102B, AF150(S)), via m1 muscarinic receptors, activate distinct signal transductions, enhance amyloid precursors proteins secretion from transfected cells and primary cell cultures, show neurotrophic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971914d532748def2f93a2dc9ef5d28e
https://doi.org/10.1016/s0928-4257(99)80001-1
https://doi.org/10.1016/s0928-4257(99)80001-1
Autor:
Eliahu Heldman, Haim Meshulam, Jacob Barg, Abraham Fisher, Rachel Haring, A. Wengier, David Gurwitz, H.D. Danenberg, Ronit Pinkas-Kramarski, Y. Karton, Z. Pittel, D. Marciano
Publikováno v:
Biochemical and Biophysical Research Communications. 213:15-23
Processing of beta-amyloid precursor protein (APP) is coupled to several neurotransmitter receptors, including m1 muscarinic (m1AChR), and is associated with decreased amyloid deposition. Muscarinic agonist-stimulated APP secretion and membrane APP w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea054acd4316154646fd0898783ecb14
https://doi.org/10.1006/bbrc.1995.2092
https://doi.org/10.1006/bbrc.1995.2092
Autor:
Abraham Fisher, Yishai Karton, Zvi Vogel, Zipora Pittel, David Gurwitz, Rachel Brandeis, Rachel Haring, Menahem Segal, Dov Barak, Eliahu Heldman, Haim Meshulam, Daniele Marciano
Publikováno v:
Annals of the New York Academy of Sciences. 695:300-303
Rigid analogs of acetylcholine (ACh) were designed for selective actions at muscarinic receptor (mAChR) subtypes and distinct second messenger systems. AF102B, AF150, and AF151 are such rigid analogs of ACh. AF102B, AF150 and AF151 are centrally acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0301b68bfffd096ced1f2ead1690ecf3
https://doi.org/10.1111/j.1749-6632.1993.tb23070.x
https://doi.org/10.1111/j.1749-6632.1993.tb23070.x
Autor:
Rachel Haring, Daniele Marciano, Eliahu Heldman, David Gurwitz, Haim Meshulam, Rachel Brandeis, Abraham Fisher, Dov Barak, Ishai Karton, Zipora Pittel, Zvi Vogel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:839-844
Rigid analogs of acetylcholine offer an opportunity for selective actions at muscarinic receptor subtypes, since restricted conformational mobility alters the capacity of ligands to adapt to subtle differences in receptor structure. AF102B , a highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d02494e2795d848cb0c6fde76898d0
https://doi.org/10.1016/s0960-894x(00)80541-7
https://doi.org/10.1016/s0960-894x(00)80541-7
Autor:
O. Limanovich, Shai Teitlboim, Gabriel Amitai, Shelly Yishay, R. Adani, Lily Raveh, Liat Tveria, Guy Yacov, Haim Meshulam
Publikováno v:
Chemico-biological interactions. 175(1-3)
Organophosphorus hydrolases (OPH) such as mammalian plama paraoxonase (PON1) detoxify asymmetric toxic organophosphorus (OP) nerve agents by preferentially hydrolyzing the less toxic P(+) optical isomer. In order to develop new OPHs with broader ster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4534967fdcb290fc9b4a421235e0ce69
https://pubmed.ncbi.nlm.nih.gov/18588863
https://pubmed.ncbi.nlm.nih.gov/18588863