Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Hailun Xia"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Sunitinib, a newly developed multi-targeted tyrosine kinase inhibitor (TKI), has become a common therapeutic option for managing advanced renal cell carcinoma (RCC). Examining the mechanism underlying the interaction between sunit
Externí odkaz:
https://doaj.org/article/88eb762f5aae4fe0a0f8b15f1fd87a9c
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 874-881 (2024)
Context Almonertinib is primarily metabolized by CYP3A4, so it could interact with a variety of drugs metabolized by CYP3A4, leading to the changes of systemic exposure.Objective For the purpose of this experiment, an ultra-performance liquid chromat
Externí odkaz:
https://doaj.org/article/1a2e8cd8b4c44c0384c3efa5674d718c
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/e5a8107d53f445dfa877f676d916b7c5
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ivacaftor is the first potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) protein approved for use alone in the treatment of cystic fibrosis (CF). Ivacaftor is primarily metabolized by CYP3A4 and therefore may interact with
Externí odkaz:
https://doaj.org/article/c55b021424b94df992213ae5b652d043
Autor:
Zhize Ye, Hailun Xia, Jinyu Hu, Ya-nan Liu, Anzhou Wang, Jian-ping Cai, Guo-xin Hu, Ren-ai Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116421- (2024)
Tofacitinib can effectively improve the clinical symptoms of rheumatoid arthritis (RA) patients. In this current study, a recombinant human CYP2C19 and CYP3A4 system was operated to study the effects of recombinant variants on tofacitinib metabolism.
Externí odkaz:
https://doaj.org/article/e521898341db4c25ac01509310f911d0
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
As a broad-spectrum antiviral, and especially as a popular drug for treating coronavirus disease 2019 (COVID‐19) today, arbidol often involves drug–drug interactions (DDI) when treating critical patients. This study established a rapid and effect
Externí odkaz:
https://doaj.org/article/6b95fff2c72944fbbd7ab0e4d71f6a6e
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Lacosamide, a third-generation novel antiepileptic drug, was first approved in 2008 as an adjunct to partial seizures. In 2014, the U.S. Food and Drug Administration (FDA) approved it as a single agent for partial seizures. Since epilepsy is a chroni
Externí odkaz:
https://doaj.org/article/67108a05abf341a5a7235695b061b1f1
Autor:
Hailun Xia, Xinkai Gao
Publikováno v:
IEEE Access, Vol 9, Pp 36475-36484 (2021)
In skeleton-based action recognition, the approaches based on graph convolutional networks(GCN) have achieved remarkable performance by modeling spatial-temporal graphs to explore the physical dependencies between body joints. However, these methods
Externí odkaz:
https://doaj.org/article/a361d49abe784318a6db4d289f74e5f9
Autor:
Hailun Xia, Meng Xiao
Publikováno v:
IEEE Access, Vol 8, Pp 206198-206206 (2020)
3D human pose estimation from a monocular RGB image is a challenging task in computer vision because of depth ambiguity in a single RGB image. As most methods consider joint locations independently which can lead to an overfitting problem on specific
Externí odkaz:
https://doaj.org/article/7a9bb165d4994b9d8d4a1de350299040
Autor:
Xinmei Song, Xiaolan Xue, Hailun Xia, Li Jin, Anyang Tao, Yaoda Wang, Junchuan Liang, Yuzhu Liu, Pengbo Zhang, Zuoxiu Tie, Yitao Long, Zhong Jin
Publikováno v:
Energy Storage Materials. 55:426-435
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e146b8621c8ff80c2aaa109dbc2e2022
https://doi.org/10.1016/j.ensm.2022.11.052
https://doi.org/10.1016/j.ensm.2022.11.052