Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Hailong Qi"'
Autor:
Hailong Qi, Zhongjie Sun, Tianle Gao, Yanling Yao, Yu Wang, Weiwei Li, Xudong Wang, Xiaofang Wang, Defang Liu, Jian-Dong Jiang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic efficacy and reduce dose-dependent
Externí odkaz:
https://doaj.org/article/12c3f4b5e99c4ee8a78a331490a652f8
Publikováno v:
Vaccines, Vol 12, Iss 8, p 873 (2024)
mRNA vaccines are leading a medical revolution. mRNA technologies utilize the host’s own cells as bio-factories to produce proteins that serve as antigens. This revolutionary approach circumvents the complicated processes involved in traditional va
Externí odkaz:
https://doaj.org/article/fbc1ad08746942c5b5d49360627c9d20
Autor:
Jianqiang Cai, Jianjun Zhao, Defang Liu, Huangfan Xie, Hailong Qi, Junfan Ma, Zhongjie Sun, Hong Zhao
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPostoperative adjuvant transcatheter arterial chemoembolization (TACE) following curative hepatectomy has been reported to improve the clinical outcomes of hepatocellular carcinoma (HCC) patients with microvascular invasion (MVI), but more
Externí odkaz:
https://doaj.org/article/095dbad9420e448d8cff6e5c5a1efd5e
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1103 (2022)
Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have been approved for clinical use. SARS-CoV-2 neutralizing antibody titers after immunization are widely used as an evaluation indicator, and the roles of cellular immun
Externí odkaz:
https://doaj.org/article/9775cea612b04469a697e366d55cf2dd
Publikováno v:
Vaccines, Vol 10, Iss 3, p 407 (2022)
SARS-CoV-2 spike (S) variants that may evade antibody-mediated immunity are emerging. Evidence shows that vaccines with a stronger immune response are still effective against mutant strains. Here, we report a targeted type 1 conventional dendritic (c
Externí odkaz:
https://doaj.org/article/e10a3f732ee44c35beb0e868a103eb38
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 126-129 (2018)
The M2 isoform of pyruvate kinase (PKM2) is a potential antitumor therapeutic target. In this study, we designed and synthesised a series of 2, 3-didithiocarbamate substituted naphthoquinones as PKM2 inhibitors based on the lead compound 3k that we p
Externí odkaz:
https://doaj.org/article/079dde823e554c6da30f7c651925427a
Autor:
Pan Wang, Fan Mei, Jiapan Hu, Minglu Zhu, Hailong Qi, Xi Chen, Ruiqi Li, Michael A. McNutt, Yuxin Yin
Publikováno v:
Cell Reports, Vol 19, Iss 12, Pp 2627-2641 (2017)
Summary: PTEN (phosphatase and tensin homology deleted on chromosome 10) has multiple functions, and recent studies have shown that the PTEN family has isoforms. The roles of these PTEN family members in biologic activities warrant specific evaluatio
Externí odkaz:
https://doaj.org/article/6b98cd98f9be4e519fb35eae0bb1abd8
Publikováno v:
Energies, Vol 13, Iss 22, p 5951 (2020)
Solar photovoltaic (PV) power generation has strong intermittency and volatility due to its high dependence on solar radiation and other meteorological factors. Therefore, the negative impact of grid-connected PV on power systems has become one of th
Externí odkaz:
https://doaj.org/article/b4cca46cb8504625bd3d079886aef590
Autor:
Shengjuan Hu, Yan Zhou, Yanhong Deng, Yang Bo, Xianmei Chen, Wei Yang, Ruichun Shi, Wei Zhao, Zhanbing Hou, Jianping Hu, Jianguo Liu, Xilong Zhang, Heli Yong, Ping Wang, Fei Li, Hailong Qi, Xiaoyun Wang, Lijuan Jin, Ting Cui, Haijiang Yong, Xue Li, Bin Yang, Yuehua Yu, Bin Ma, Lei Fu, Xuemei Wang, Zhen Ma, Na Tang, Yanjie You, Jianyang Guo, Xiaobing Yu, Li Yao, Ruiping Gao, Yanling Li, Ruijuan Xin, Jianfang Liu, Zhenzi Cao, Hongliang Li, Linke Ma, Shoucheng Ma, Ying Cao, Yuanyuan Tang, Jun Liu, Qian Hao, Xiaofei Li, Xuemei Li, Rui Mu, Min Niu, Xiaoming Su, Hengjun Gao
Publikováno v:
Helicobacter. 28
Autor:
Xianling, Ning, Hailong, Qi, Yuyao, Yuan, Ridong, Li, Yuanyuan, Wang, Zhiqiang, Lin, Yuxin, Yin
Publikováno v:
European journal of pharmacology. 934
Ferroptosis is a non-apoptotic cell death characterized by iron-mediated ROS accumulation and increasing lipid peroxidation. The activation of ferroptosis results in the destruction of cancer cells and overcoming the drug resistance associated with e