Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hailong Mi"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Exploring the mechanism of breast cancer metastasis and searching for new drug therapeutic targets are still the focuses of current research. RNA-binding proteins (RBPs) may affect breast cancer metastasis by regulating alternative splicing
Externí odkaz:
https://doaj.org/article/e517bb9553544f3ba515a42b51c5b1a3
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
Autor:
Huan Li, Chao Song, Yang Zhang, Guohao Liu, Hailong Mi, Yachao Li, Zhiye Chen, Xiaoyu Ma, Po Zhang, Lidong Cheng, Peng Peng, Hongtao Zhu, Zirong Chen, Minhai Dong, Sui Chen, Hao Meng, QunGen Xiao, Honglian Li, Qiulian Wu, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Dongsheng Guo, Wenchao Zhou, Lin Zhou, Feng Mao, Jeremy N. Rich, Xingjiang Yu
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) is a lethal cancer characterized by hypervascularity and necrosis associated with hypoxia. Here, it is found that hypoxia preferentially induces the actin‐binding protein, Transgelin (TAGLN), in GBM stem cells (GSCs). Me
Externí odkaz:
https://doaj.org/article/95216e81a5c74d7e8e6af9ccdf165215
Autor:
Fang Wang, Jingruo Li, Lin Li, Zhuo Chen, Nan Wang, Mingzhi Zhu, Hailong Mi, Youyi Xiong, Guangcheng Guo, Yuanting Gu
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Breast cancer (BC) threatens the health of women around the world. Researchers have proved that hsa_circ_0005505 (circ_IRAK3) facilitates BC cell invasion and migration, but the regulatory mechanisms of circ_IRAK3 in BC remain mos
Externí odkaz:
https://doaj.org/article/9b4ef1953e104a96815dcc892c5f1a5e
Autor:
Cuifang Ye, Huan Li, Yachao Li, Yang Zhang, Guohao Liu, Hailong Mi, Honglian Li, Qungen Xiao, Li Niu, Xingjiang Yu
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104872- (2022)
Summary: Glioma stem cells (GSCs) in the hypoxic niches contribute to tumor initiation, progression, and recurrence in glioblastoma (GBM). Hypoxia induces release of high-mobility group box 1 (HMGB1) from tumor cells, promoting the development of tum
Externí odkaz:
https://doaj.org/article/cd8cbc0aa2f84355b2eceee8f11724a6
Autor:
Hongtao Zhu, Dan Liu, Lidong Cheng, Jingdian Liu, Guanghui Wang, Huan Li, Yang Zhang, Hailong Mi, Suojun Zhang, Kai Shu, Xingjiang Yu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Malignant glioma is the most common solid tumor of the adult brain, with high lethality and poor prognosis. Hence, identifying novel and reliable biomarkers can be advantageous for diagnosing and treating glioma. Several galectins encoded by LGALS ge
Externí odkaz:
https://doaj.org/article/98c1156444324a1882fbf91940f9a614
Publikováno v:
Cancer Management and Research. 14:3245-3269
Cofilin, as a depolymerization factor of actin filaments, has been widely studied. Evidences show that cofilin has a role in actin structural reorganization and dynamic regulation. In recent years, several studies have demonstrated a regulatory role
Publikováno v:
Cell Cycle
Breast cancer remains a general-threat event in the health of women. Currently, increasing records indicate that long non-coding RNA maternally expressed 3 (MEG3) plays a central role in breast cancer. The current research focused on the function of
Autor:
Yuanting Gu, Xiaochun Wang, Nan Wang, Youyi Xiong, Fang Wang, Hailong Mi, Lin Li, Mingzhi Zhu
Publikováno v:
OncoTargets and Therapy. 13:657-666
Background Increasing evidence implies the participation of long non-coding RNAs (lncRNAs) in chemoresistance to cancer treatment. Their role and molecular mechanisms in breast cancer chemoresistance, nevertheless, are yet not considerably elucidated
Autor:
Hailong Mi, Nan Wang, Yuanting Gu, Fang Wang, Pengwei Lv, Lin Li, Mingzhi Zhu, Mingti Fu, Youyi Xiong, Chaochao Zhong
Publikováno v:
OncoTargets and Therapy. 12:10671-10679
Introduction Long non-coding RNAs (lncRNAs) were found to regulate many biological processes including cancer development, immunology and other diseases. LncRNA HULC was found to be oncogenes in many cancer progression. However, the role of HULC in t
Autor:
Youyi Xiong, Hailong Mi, Nan Wang, Fang Wang, Lin Li, Mingzhi Zhu, Xiaochun Wang, Yuanting Gu
Publikováno v:
European Journal of Pharmacology. 839:66-75
The emergence of drug resistance is still a daunting challenge for the effective therapy of cancer patients. miRNAs have been elucidated as an important regulator in chemoresistance of anti-cancer drugs. miR-381 is found to exert tumor-suppressive ef