Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Hailiang Sun"'
Autor:
Feng Guo, Xianglin Ji, Chuxiao Xiong, Hailiang Sun, Zhenghua Liang, Richard Yan-Do, Baowen Gai, Feng Gao, Linfeng Huang, Zhongping Li, Becki Yi Kuang, Peng Shi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The use of combinatorial siRNAs shows great promise for drug discovery, but the identification of safe and effective siRNA combinations remains challenging. Here, we develop a massively multiplexed technology for systematic screening of siRN
Externí odkaz:
https://doaj.org/article/bb06ba9b06864a35bb1181bea8bef155
Autor:
Zaolan Liang, Xia Lin, Lihong Sun, Kimberly M. Edwards, Wenjun Song, Hailiang Sun, Yanmin Xie, Fangmei Lin, Shiman Ling, Tingting Liang, Biying Xiao, Jiaqi Wang, Min Li, Chin-Yu Leung, Huachen Zhu, Nisha Bhandari, Raghavan Varadarajan, Min Z. Levine, Malik Peiris, Robert Webster, Vijaykrishna Dhanasekaran, Nancy H. L. Leung, Benjamin J. Cowling, Richard J. Webby, Mariette Ducatez, Mark Zanin, Sook-San Wong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pandemic, we investigate the reacti
Externí odkaz:
https://doaj.org/article/222177c2a96944b098415e28af694ad7
Autor:
Hailiang Sun, Yongcui Wang, Hanlin Liu, Zifeng Pang, Xinxin Cui, Rui Zhao, Yanwei Liu, Xiaoyun Qu, Mian Huang, Changwen Ke, Ming Liao
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundThe 2009 pandemic H1N1 influenza A virus (pdm09) continue to evolve, and few studies have systemically analyzed the evolution, replication, and transmission of pmd09 viruses in China.MethodsTo better understand the evolution and pathogenici
Externí odkaz:
https://doaj.org/article/0805116e72564e2eb39ff54784be19ae
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Progranulin (PGRN) plays an important role in influenza virus infection. To gain insight into the potential molecular mechanisms by which PGRN regulates influenza viral replication, proteomic analyzes of whole mouse lung tissue from wild-type (WT) ve
Externí odkaz:
https://doaj.org/article/581a1fe156ca4c3cb1e5d7273f8d4c5d
Autor:
Weiqiang Li, Yating Song, Yuqing Du, Zhanhong Huang, Meng Zhang, Zuxian Chen, Zhuoliang He, Yangbao Ding, Junsheng Zhang, Luxiang Zhao, Hailiang Sun, Peirong Jiao
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
The innate immune response is a host defense mechanism that induces type I interferon and proinflammatory cytokines. Tripartite motif (TRIM) family proteins have recently emerged as pivotal regulators of type I interferon production in mammals. Here,
Externí odkaz:
https://doaj.org/article/23a87160521e4380b302115ea23707b9
Autor:
Xinxin Cui, Jinhuan Ma, Zifeng Pang, Lingzhi Chi, Cuishan Mai, Hanlin Liu, Ming Liao, Hailiang Sun
Publikováno v:
Virologica Sinica (16740769); Apr2024, Vol. 39 Issue 2, p205-217, 13p
Publikováno v:
Natural Gas Industry B, Vol 7, Iss 3, Pp 278-284 (2020)
Laboratory hydrate formation process simulation provides a theoretical support for determining the dynamic revolution behaviors of actual hydrate reservoirs. In view of this, based on the ITS electrical resistance tomography (ERT) module, a dedicated
Externí odkaz:
https://doaj.org/article/61b9f058c6f040a98e3e7102afc073ad
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Since the outbreak of SARS-CoV-2 in 2019, the Chinese horseshoe bats were considered as a potential original host of SARS-CoV-2. In addition, cats, tigers, lions, mints, and ferrets were naturally or experimentally infected with SARS-CoV-2. For the s
Externí odkaz:
https://doaj.org/article/31bfbc7b30a74559a623ad0e4aad7109
Publikováno v:
Viruses, Vol 15, Iss 2, p 391 (2023)
Oxidative stress plays a vital role in viral replication. Tripartite motif containing 16 (TRIM16) is involved in diverse cellular processes. However, the role of TRIM16 in oxidative stress induced by infection of the highly pathogenic H5N1 avian infl
Externí odkaz:
https://doaj.org/article/6c7363fd5dec43ff8247ac09695ff21b
Publikováno v:
Viruses, Vol 14, Iss 8, p 1752 (2022)
The clade 2.3.4.4b H5N8 avian influenza viruses (AIVs) have caused the loss of more than 33 million domestic poultry worldwide since January 2020. Novel H5N6 reassortants with hemagglutinin (HA) from clade 2.3.4.4b H5N8 AIVs are responsible for multi
Externí odkaz:
https://doaj.org/article/bdba514ebafd4a8c833ae41cda4f91b2