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of 2
pro vyhledávání: '"Hailey Doyle"'
Autor:
Cédric Diot, Aurian P. García-González, Andre F. Vieira, Melissa Walker, Megan Honeywell, Hailey Doyle, Olga Ponomarova, Yomari Rivera, Huimin Na, Hefei Zhang, Michael Lee, Carissa P. Olsen, Albertha J. M. Walhout
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, Diot et al. use the nematode Caenorhabditis elegans as a model to identify off-target toxicity mechanisms for tamoxifen, and find that these include fatty acid metabolism and cell death, which can be modulated by different bacterial species.
Externí odkaz:
https://doaj.org/article/d1e6384868304dae8858d56f74222a07
Autor:
Cédric Diot, Aurian P. García-González, Andre F. Vieira, Melissa Walker, Megan Honeywell, Hailey Doyle, Olga Ponomarova, Yomari Rivera, Huimin Na, Hefei Zhang, Michael Lee, Carissa P. Olsen, Albertha J.M. Walhout
Publikováno v:
Nature communications. 13(1)
Tamoxifen is a selective estrogen receptor (ER) modulator that is used to treat ER-positive breast cancer, but that at high doses kills both ER-positive and ER-negative breast cancer cells. We recapitulate this off-target effect in Caenorhabditis ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2db983811451915972fe561aa6c23eb
https://pubmed.ncbi.nlm.nih.gov/36151093
https://pubmed.ncbi.nlm.nih.gov/36151093