Výsledky vyhledávání

SPE-HPLC-MS/MS method for the trace analysis of tobacco-specific N -nitrosamines and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in rabbit plasma using tetraazacalix[2]arene[2]triazine-modified silica as a sorbent

Autor: Jianxun Zhang, Sheng Wang, Qidong Zhang, Wenjie Zhao, Hailei Lang, Shusheng Zhang, Chunqiang Yang, Lei Wang

Publikováno v: Journal of Separation Science. 36:2664-2671

Tobacco-specific N-nitrosamines (TSNAs), including N'-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, N'-nitrosoanatabine, and N'-nitrosoanabasine, have been implicated as a source of carcinogenicity in tobacco and cigarette smoke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7b7b303de4ce030108923c702be55e
https://doi.org/10.1002/jssc.201300219

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Simultaneous determination of NNK and its seven metabolites in rabbit blood by hydrophilic interaction liquid chromatography–tandem mass spectrometry

Autor: Qidong Zhang, Juan Wang, Mao Jian, Baojun Cao, Sheng Wang, Jianxun Zhang, Hailei Lang, Beibei Zhao, Lei Wang

Publikováno v: Analytical and Bioanalytical Chemistry. 405:2083-2089

A hydrophilic interaction liquid chromatographic-tandem mass spectrometric (HILIC-MS-MS) method for investigation of the in vivo metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a potent carcinogen, in rabbit blood has been develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050673181d1e1da3e671a5978549659f
https://doi.org/10.1007/s00216-012-6641-z

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Simultaneous determination of NNK and its metabolites in mouse tissue for evaluating the effects of chronic alcohol consumption on the metabolism of NNK in mouse liver and lung

Autor: Houwei Ji, Mingfei Feng, Junhui Liu, Baojun Cao, Qidong Zhang, Hailei Lang, Jianxun Zhang

Publikováno v: Analytical and bioanalytical chemistry. 406(18)

A hydrophilic-interaction liquid chromatography-tandem mass spectrometry (HILIC-MS-MS) method was developed for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its metabolites in mouse liver and lung. The limits of detec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416b127bb028716e0d39df8d9dd3b73e
https://pubmed.ncbi.nlm.nih.gov/24817362

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Analysis of N'-nitrosonornicotine and its metabolites in rabbit blood with liquid chromatography/tandem mass spectrometric method

Autor: Shihao Sun, Sheng Wang, Beibei Zhao, Mao Jian, Hailei Lang, Jianxun Zhang, Juan Wang

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 899

N′-nitrosonornicotine (NNN) is a strong carcinogen. The metabolic study of NNN in vivo will help us to further understand it, however, trace detection in complex matrices requires highly sensitive detection methods. After the chromatographic condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820b609cc9ce4f9a28ec7274bb25eaf2
https://pubmed.ncbi.nlm.nih.gov/22647942

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Erratum to: Simultaneous determination of NNK and its seven metabolites in rabbit blood by hydrophilic interaction liquid chromatography–tandem mass spectrometry

Autor: Hailei Lang, Sheng Wang, Qidong Zhang, Beibei Zhao, Lei Wang, Baojun Cao, Juan Wang, Jian Mao, Jianxun Zhang

Publikováno v: Analytical and Bioanalytical Chemistry. 405:5615-5615

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddd9435db86947743c1e36cb9d71c375
https://doi.org/10.1007/s00216-013-6966-2

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