Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hailan Yao"'
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 39, Iss , Pp 59-68 (2024)
Objectives: The rising threat of antibiotic resistance poses a significant challenge to public health. The research on the new direction of resistance mechanisms is crucial for overcoming this hurdle. This study examines metabolic changes by comparin
Externí odkaz:
https://doaj.org/article/f67f8bcb5b024317a3a0e8a72f36fa9f
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35326- (2024)
Background: Staphylococcus aureus (S. aureus), a prevalent human pathogen known for its propensity to cause severe infections, has exhibited a growing resistance to antibiotics. Lysine acetylation (Kac) is a dynamic and reversible protein post-transl
Externí odkaz:
https://doaj.org/article/79eed497e13e46db83655c338dcc62ae
Publikováno v:
Atmosphere, Vol 14, Iss 7, p 1071 (2023)
Extreme meteorological events can influence air quality. In March 2021, northern China experienced a severe dust event, leading to widespread air quality deterioration. Using reanalysis datasets and station data, we investigate the synoptic weather p
Externí odkaz:
https://doaj.org/article/c82615fd388940ed9855074c4067a3a4
Autor:
Ruifang Wang, Kexin Zong, Juan Song, Qinqin Song, Dong Xia, Mi Liu, Haijun Du, Zhiqiang Xia, Hailan Yao, Jun Han
Publikováno v:
Viruses, Vol 15, Iss 5, p 1137 (2023)
Viral myocarditis (VMC) is a common disease characterized by cardiac inflammation. AC-73, an inhibitor of CD147, disrupts the dimerization of CD147, which participates in the regulation of inflammation. To explore whether AC-73 could alleviate cardia
Externí odkaz:
https://doaj.org/article/8f8462887519438bb64b0043e459e478
Autor:
Yanling Feng, Guanhua Xue, Junxia Feng, Chao Yan, Jinghua Cui, Lin Gan, Rui Zhang, Hanqin Zhao, Wenjian Xu, Nannan Li, Shiyu Liu, Shuheng Du, Weiwei Zhang, Hailan Yao, Jun Tai, Lijuan Ma, Ting Zhang, Dong Qu, Yongxiang Wei, Jing Yuan
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
New Delhi metallo-β-lactamase, a metallo-β-lactamase carbapenemase type, mediates resistance to most β-lactam antibiotics including penicillins, cephalosporins, and carbapenems. Therefore, it is important to detect blaNDM genes in children’s cli
Externí odkaz:
https://doaj.org/article/d1e7c9b3aea14059903b315f2c7f7f8b
Autor:
Feng He, Zonghui Xiao, Hailan Yao, Sen Li, Miao Feng, Wei Wang, Zhewei Liu, Zhuo Liu, Jianxin Wu
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background The P38 mitogen-activated protein kinase (MAPK) pathway plays an essential role in CVB3-induced diseases. We previously demonstrated microRNA-21 has potential inhibitory effect on the MAP2K3 which locates upstream of P38 MAPK and
Externí odkaz:
https://doaj.org/article/3f7d2fa24d8f425e8d69201f848f07dc
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Interleukin (IL)-37 has emerged as a novel anti-inflammatory cytokine that play an immunosuppressive role in regulating inflammatory response. This study aimed to measure IL-37 levels in the plasma and peripheral blood mononuclear
Externí odkaz:
https://doaj.org/article/1e6530e8184442949955cc99ffe6d4b0
Autor:
Jonas Elias Schweig, Hailan Yao, David Beaulieu-Abdelahad, Ghania Ait-Ghezala, Benoit Mouzon, Fiona Crawford, Michael Mullan, Daniel Paris
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-25 (2017)
Abstract The pathology of Alzheimer’s disease (AD) is characterized by dystrophic neurites (DNs) surrounding extracellular Aβ-plaques, microgliosis, astrogliosis, intraneuronal tau hyperphosphorylation and aggregation. We have previously shown tha
Externí odkaz:
https://doaj.org/article/3df914653fbb490c9478c2c0d2e6afe0
Autor:
Juanjuan Li, Junhui Li, Jianguo Li, Hailan Yao, Fang Liu, James F Gusella, Xiaodong Shi, Xiaoli Chen
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 11, Pp n/a-n/a (2019)
Abstract Background Pediatric myelodysplastic syndromes (MDS) display clonal genomic instability that can lead to acquisition of other hematological disorders, usually by loss of heterozygosity. Immunodeficiency caused by uniparental disomy (UPD) has
Externí odkaz:
https://doaj.org/article/e5cbd2c2f69643a491adea9f5029a250
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Several genetic variants of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) have been shown to increase the risk of developing Alzheimer’s disease (AD) supporting a role of microglia and immune cells in the pathobiology of AD. We have
Externí odkaz:
https://doaj.org/article/b2c8987ae5ab49f488f1f60efe1afd9c