Výsledky vyhledávání

Akademický článek

Molecular identification of wines using in situ liquid SIMS and PCA analysis

Autor: Cuixia Cheng, Yadong Zhou, Holden M. Nelson, Tasneem Ahmadullah, Hailan Piao, Zhaoying Wang, Wenxiao Guo, Jun-Gang Wang, Guosong Lai, Zihua Zhu

Publikováno v: Frontiers in Chemistry, Vol 11 (2023)

Composition analysis in wine is gaining increasing attention because it can provide information about the wine quality, source, and nutrition. In this work, in situ liquid secondary ion mass spectrometry (SIMS) was applied to 14 representative wines,

Externí odkaz: https://doaj.org/article/8b79378732f14b39aee80d97145204e0

Zobrazit plný text záznamu

Supplementary Methods from Construction of an Immunotoxin, D2C7-(scdsFv)-PE38KDEL, Targeting EGFRwt and EGFRvIII for Brain Tumor Therapy

Autor: Darell D. Bigner, Ira H. Pastan, Chien-Tsun Kuan, Roger E. McLendon, Carol J. Wikstrand, Hailan Piao, Scott E. Szafranski, Charles N. Pegram, Stephen T. Keir, Xuhui Bao, Vidyalakshmi Chandramohan

Supplementary Methods - PDF file 94K, The supplementary methods section describes the following: Construction, expression and purification of different EGFRvIII deletion mutants, cloning of variable heavy (VH) and variable light (VL) domains of P588

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9fc021499967905c42beb95c7bfd54
https://doi.org/10.1158/1078-0432.22447884.v1

Zobrazit plný text záznamu

Supplementary Figures 1-9 from Construction of an Immunotoxin, D2C7-(scdsFv)-PE38KDEL, Targeting EGFRwt and EGFRvIII for Brain Tumor Therapy

Supplementary Figures 1-9 - Supplementary Figures 1-9 - PDF file 516K, Supplementary Figure S1. Deduced amino acid sequence of the D2C7 scFv cloned from D2C7 hybridoma. VH (A) and VL (B) antigen-binding regions of the D2C7 scFv. Amino acid numbering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3c8becb44d363b42717644935e5b6d
https://doi.org/10.1158/1078-0432.22447887

Zobrazit plný text záznamu

Data from Construction of an Immunotoxin, D2C7-(scdsFv)-PE38KDEL, Targeting EGFRwt and EGFRvIII for Brain Tumor Therapy

Purpose: The EGF receptor gene (EGFR) is most frequently amplified and overexpressed, along with its deletion mutant, EGFRvIII, in glioblastoma. We tested the preclinical efficacy of the recombinant immunotoxin, D2C7-(scdsFv)-PE38KDEL, which is react

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f430ba6f517228132aa45ef5e49135
https://doi.org/10.1158/1078-0432.c.6521244.v1

Zobrazit plný text záznamu

Proteome specialization of anaerobic fungi during ruminal degradation of recalcitrant plant fiber

Publikováno v: The ISME Journal
ISME Journal
ISME Journal, 2021, 15 (2), pp.421-434. ⟨10.1038/s41396-020-00769-x⟩
ISME Journal, Nature Publishing Group, 2021, 15 (2), pp.421-434. ⟨10.1038/s41396-020-00769-x⟩
The ISME journal, vol 15, iss 2

The rumen harbors a complex microbial mixture of archaea, bacteria, protozoa and fungi that efficiently breakdown plant biomass and its complex dietary carbohydrates into soluble sugars that can be fermented and subsequently converted into metabolite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108be42b230d4b85b99bb8286a839728
http://europepmc.org/articles/PMC8026616

Zobrazit plný text záznamu

A 2.08 Å resolution structure of HLB5, a novel cellulase from the anaerobic gut bacterium Parabacteroides johnsonii DSM 18315

Autor: Gyorgy Babnigg, Hailan Piao, Matthias Hess, Jamey C. Mack, Charles G. Brooke, Changsoo Chang, Andrzej Joachimiak

Publikováno v: Protein science : a publication of the Protein Society, vol 28, iss 4

Cellulases play a significant role in the degradation of complex carbohydrates. In the human gut, anaerobic bacteria are essential to the well-being of the host by producing these essential enzymes that convert plant polymers into simple sugars that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023aa607fac1719e0cca6ca73f076b16
https://doi.org/10.1002/pro.3582

Zobrazit plný text záznamu

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

Autor: Zhen Zhang, Chen Lin, Hailan Piao, L. Xie, Xuhui Bao, Darell D. Bigner, Qingfu Zhang

Publikováno v: Cancer Management and Research

Liyi Xie,1–3 Chen Lin,4 Qingfu Zhang,5 Hailan Piao,6 Darell D Bigner,3,7 Zhen Zhang,1,2 Xuhui Bao8 1Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; 2Department of Oncology, Shanghai Medical College, Fudan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8541623dcdab098bc41c4dccad2e2e48
https://doi.org/10.2147/cmar.s163510

Zobrazit plný text záznamu

Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial

Autor: Darell D. Bigner, Scott E. Szafranski, Chien-Tsun Kuan, Charles N. Pegram, Ira Pastan, Vidyalakshmi Chandramohan, Hailan Piao

Publikováno v: Applied Microbiology and Biotechnology. 101:2747-2766

D2C7-(scdsFv)-PE38KDEL (D2C7-IT) is a novel recombinant Pseudomonas exotoxin A-based immunotoxin (IT), targeting both wild-type epidermal growth factor receptor (EGFRwt) and mutant EGFR variant III (EGFRvIII) proteins overexpressed in glioblastomas.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914855de5a7df46007c7254cec087f67
https://doi.org/10.1007/s00253-016-8063-x

Zobrazit plný text záznamu

Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy

Autor: Shengli Zhao, Xiu-Rong Ren, Jiangbo Wang, Herbert Kim Lyerly, Hailan Piao, Wei Chen, Michael A. Morse, Robert A. Mook, Takuya Osada, Richard T. Premont

The Wnt signaling pathway, known for regulating genes critical to normal embryonic development and tissue homeostasis, is dysregulated in many types of cancer. Previously, we identified that the anthelmintic drug niclosamide inhibited Wnt signaling b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a37212059ac5ed8f9e1c2b56b66efd5
https://europepmc.org/articles/PMC6643999/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání