Three-Year Outcomes of Oral Antibiotics vs Intravenous and Oral Antibiotics for Uncomplicated Acute Appendicitis: A Secondary Analysis of the APPAC II Randomized Clinical Trial.

Autor: Selänne L; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Haijanen J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Sippola S; Department of Surgery, Helsinki University Hospital, Helsinki, Finland., Hurme S; Department of Biostatistics, University of Turku and Turku University Hospital, Turku, Finland., Rautio T; Department of Surgery, Oulu University Hospital, Oulu, Finland.; Medical Research Center Oulu, University of Oulu, Oulu, Finland., Nordström P; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland., Rantanen T; Department of Surgery, Kuopio University Hospital, Kuopio, Finland.; Department of Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Pinta T; Department of Surgery, Seinäjoki Central Hospital, Seinäjoki, Finland., Ilves I; Department of Surgery, Mikkeli Central Hospital, Mikkeli, Finland., Mattila A; Wellbeing Services County of Central Finland, Hospital Nova of Central Finland, Jyväskylä, Finland., Rintala J; Department of Surgery, Oulu University Hospital, Oulu, Finland.; Department of Surgery, Rovaniemi Central Hospital, Rovaniemi, Finland., Marttila H; Department of Hospital Hygiene and Infection Control, Turku University Hospital, Turku, Finland., Meriläinen S; Department of Surgery, Oulu University Hospital, Oulu, Finland.; Medical Research Center Oulu, University of Oulu, Oulu, Finland., Laukkarinen J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland., Sävelä EL; Department of Surgery, Satakunta Central Hospital, Pori, Finland., Paajanen H; Department of Surgery, Mikkeli Central Hospital, Mikkeli, Finland., Grönroos J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Salminen P; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland.; Department of Surgery, Satakunta Central Hospital, Pori, Finland.

Publikováno v: JAMA surgery [JAMA Surg] 2024 Jul 01; Vol. 159 (7), pp. 727-735.

Appendiceal microbiome in uncomplicated and complicated acute appendicitis: A prospective cohort study.

Autor: Vanhatalo S; Research Center for Infections and Immunity, Institute of Biomedicine, University of Turku, Turku, Finland.; Laboratory Division, Department of Clinical Microbiology, Turku University Hospital, Turku, Finland., Munukka E; Faculty of Medicine, Microbiome Biobank, University of Turku and Turku University Hospital, Turku, Finland.; Biocodex Nordics, Espoo, Finland., Kallonen T; Research Center for Infections and Immunity, Institute of Biomedicine, University of Turku, Turku, Finland.; Laboratory Division, Department of Clinical Microbiology, Turku University Hospital, Turku, Finland.; Faculty of Medicine, Microbiome Biobank, University of Turku and Turku University Hospital, Turku, Finland., Sippola S; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Grönroos J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Haijanen J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Hakanen AJ; Research Center for Infections and Immunity, Institute of Biomedicine, University of Turku, Turku, Finland.; Laboratory Division, Department of Clinical Microbiology, Turku University Hospital, Turku, Finland.; Faculty of Medicine, Microbiome Biobank, University of Turku and Turku University Hospital, Turku, Finland., Salminen P; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland.

Publikováno v: PloS one [PLoS One] 2022 Oct 14; Vol. 17 (10), pp. e0276007. Date of Electronic Publication: 2022 Oct 14 (Print Publication: 2022).

Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial.

Autor: Salminen P; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Sippola S; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland.; Department of Surgery, Jyväskylä Central Hospital, Jyväskylä, Finland., Haijanen J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Nordström P; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland., Rantanen T; Department of Surgery, Kuopio University Hospital, Kuopio, Finland.; Department of Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Rautio T; Department of Surgery, Oulu University Hospital, Oulu, Finland.; Medical Research Centre Oulu, University of Oulu, Oulu, Finland., Sallinen V; Gastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Löyttyniemi E; Department of Biostatistics, University of Turku, Turku, Finland., Hurme S; Department of Biostatistics, University of Turku, Turku, Finland., Tammilehto V; Department of Radiology, Turku University Hospital, Turku, Finland., Laukkarinen J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland., Savolainen H; Department of Surgery, Kuopio University Hospital, Kuopio, Finland.; Department of Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Meriläinen S; Department of Surgery, Oulu University Hospital, Oulu, Finland.; Medical Research Centre Oulu, University of Oulu, Oulu, Finland., Leppäniemi A; Gastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Grönroos J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland.

Publikováno v: The British journal of surgery [Br J Surg] 2022 May 16; Vol. 109 (6), pp. 503-509.

Diagnostic accuracy using low-dose versus standard radiation dose CT in suspected acute appendicitis: prospective cohort study.

Autor: Haijanen J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Sippola S; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland.; Department of Surgery, Jyväskylä Central Hospital, Jyväskylä, Finland., Tammilehto V; Department of Radiology, Medical Imaging Centre of Southwest Finland, Turku University Hospital, Turku, Finland., Grönroos J; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Mäntyoja S; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland., Löyttyniemi E; Department of Biostatistics, University of Turku, Turku, Finland., Niiniviita H; Department of Radiology, Medical Imaging Centre of Southwest Finland, Turku University Hospital, Turku, Finland.; Department of Medical Physics, Turku University Hospital, Turku, Finland., Salminen P; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.; Department of Surgery, University of Turku, Turku, Finland.

Publikováno v: The British journal of surgery [Br J Surg] 2021 Dec 01; Vol. 108 (12), pp. 1483-1490.

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