Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Haihua Xiao"'
Autor:
Hanchen Zhang, Nicolás Montesdeoca, Dongsheng Tang, Ganghao Liang, Minhui Cui, Chun Xu, Lisa-Marie Servos, Tiejun Bing, Zisis Papadopoulos, Meifang Shen, Haihua Xiao, Yingjie Yu, Johannes Karges
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract The majority of anticancer agents have a reduced or even complete loss of a therapeutic effect within hypoxic tumors. To overcome this limitation, research efforts have been devoted to the development of therapeutic agents with biological me
Externí odkaz:
https://doaj.org/article/9ebf02fca74846939ced22799b624dfa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Cationic polymers have great potential for cancer therapy due to their unique interactions with cancer cells. However, their clinical application remains limited by their high toxicity. Here we show a cell membrane-targeting cationic polymer
Externí odkaz:
https://doaj.org/article/b169713cf709467d9e1e7087d4e43a02
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Glaucoma is an irreversible blinding eye disease characterized by retinal ganglion cell (RGC) death.Previous studies have demonstrated that protecting mitochondria and activating the CaMKII/CREB signaling pathway can effectively protect RGC
Externí odkaz:
https://doaj.org/article/c55a79cb476a4872b961d03aeb13884a
Autor:
Fanqiang Bu, Xiaoxu Kang, Dongsheng Tang, Fang Liu, Lin Chen, Pengfei Zhang, Wenli Feng, Yingjie Yu, Guofeng Li, Haihua Xiao, Xing Wang
Publikováno v:
Bioactive Materials, Vol 33, Iss , Pp 341-354 (2024)
Nitric oxide (NO) enhanced photodynamic therapy (PDT) is a promising approach to overcome drug tolerance and resistance to biofilm but is limited by its short excitation wavelengths and low yield of reactive oxygen species (ROS). Herein, we develop a
Externí odkaz:
https://doaj.org/article/23f7d3db4b5c454abb3923c65c5cc2d3
Autor:
Fangzhou Chen, Lin Liu, Dongsheng Tang, Hanchen Zhang, Nier Wu, Lin Wang, Hongbo Li, Haihua Xiao, Dongsheng Zhou
Publikováno v:
Advanced Science, Vol 11, Iss 17, Pp n/a-n/a (2024)
Abstract Mild‐heat photothermal antibacterial therapy avoids heat‐induced damage to normal tissues but causes bacterial tolerance. The use of photothermal therapy in synergy with chemodynamic therapy is expected to address this issue. Herein, two
Externí odkaz:
https://doaj.org/article/fb197ff14ec3400ab893d1c7b5099220
Publikováno v:
Materials Today Advances, Vol 21, Iss , Pp 100457- (2024)
Externí odkaz:
https://doaj.org/article/b4a699d140194c20a6e2f9fabc1d4920
Autor:
Huiling Zhou, Dongsheng Tang, Yingjie Yu, Lingpu Zhang, Bin Wang, Johannes Karges, Haihua Xiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Tumor metastases are considered the leading cause of cancer-associated deaths. While clinically applied drugs have demonstrated to efficiently remove the primary tumor, metastases remain poorly accessible. To overcome this limitation, herein
Externí odkaz:
https://doaj.org/article/019475404bf544f7bf3e49365cf861e2
Autor:
Yongchao Gao, Hanchen Zhang, Lin Tang, Feifei Li, Li Yang, Haihua Xiao, Johannes Karges, Weihua Huang, Wei Zhang, Chaoyong Liu
Publikováno v:
Advanced Science, Vol 11, Iss 4, Pp n/a-n/a (2024)
Abstract Poor immunogenicity seriously hampers the broader implementation of antitumor immunotherapy. Enhanced immunogenicity capable of achieving greater antitumor immunity is urgently required. Here, a novel polymer that contains hydrophobic ferroc
Externí odkaz:
https://doaj.org/article/39ec65a897da43c590aac496dd00cde9
Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract Photodynamic therapy (PDT) has been widely employed in tumor treatment due to its effectiveness. However, the tumor hypoxic microenvironment which is caused by abnormal vasculature severely limits the efficacy of PDT. Furthermore, the abnorm
Externí odkaz:
https://doaj.org/article/498b7e3aab54476facdb916003de27f4
Autor:
Hui Tao, Jia Tan, Hanchen Zhang, Hong Ren, Ziyi Cai, Hanhan Liu, Bingyu Wen, Jiaqi Du, Gaoyang Li, Shijie Chen, Haihua Xiao, Zhihong Deng
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract The cGAS‐STING pathway, as a vital innate immune signaling pathway, has attracted considerable attention in tumor immunotherapy research. However, STING agonists are generally incapable of targeting tumors, thus limiting their clinical app
Externí odkaz:
https://doaj.org/article/b881673f00de40cf8188ca368386c4fe