Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Haihe WANG"'
Autor:
Wanhua Cai, Dade Rong, Jiayu Ding, Xiaomei Zhang, Yuwei Wang, Ying Fang, Jing Xiao, Shulan Yang, Haihe Wang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Microtubule polymerization is usually considered as the upstream of apoptotic cell death induced by taxanes, but recently published studies provide more insights into the mechanisms responsible for the antineoplastic effect of tax
Externí odkaz:
https://doaj.org/article/cb2d25d1f4fe429291e1fa9d88ce13bb
Publikováno v:
Liver Research, Vol 7, Iss 1, Pp 56-70 (2023)
Autophagy is a highly conserved process in which cytosolic contents are degraded by the lysosome, which plays an important role in energy and nutrient balance, and protein or organelle quality control. The liver is the most important organ for metabo
Externí odkaz:
https://doaj.org/article/cf7c6647f777429c8375a148196780e9
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10610- (2022)
Objective: We tried to identify novel molecular subtypes of acute myeloid leukemia (AML) associated with histone methylation and established a relevant scoring system to predict treatment response and prognosis of AML. Methods: Gene expression data a
Externí odkaz:
https://doaj.org/article/903b1fb5ba894ca49e7ad3a97476bc68
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGut microbiome plays a crucial role in the formation and progression of colorectal cancer (CRC). To better identify the underlying gene-level pathogenic mechanisms of microbiome-associated CRC, we applied our newly developed Reverse Microbi
Externí odkaz:
https://doaj.org/article/e6daf9de66774d66942d46800af50ead
Autor:
Jie Yuan, Jianchen Yu, Yun Huang, Zhenjian He, Jia Luo, Yun Wu, Yingchun Zheng, Jueheng Wu, Xun Zhu, Haihe Wang, Mengfeng Li
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Zika virus (ZIKV) infection is a global health problem, and its complications, including congenital Zika syndrome and Guillain-Barré syndrome, constitute a continued threat to humans. Unfortunately, effective therapeutics against
Externí odkaz:
https://doaj.org/article/1025291a14314950bfa7cffe2e15e366
Autor:
Hui Li, Mingming Zhang, Yanli Wei, Farhan Haider, Yitong Lin, Wen Guan, Yanbin Liu, Shaoyang Zhang, Ronghua Yuan, Xia Yang, Shulan Yang, Haihe Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-17 (2020)
Abstract Background HER2-positive breast cancer is usually associated to the more aggressive progression and the worse prognosis, but the mechanism underlying the innate resistance to HER2-targeted therapy remains elusive. The scaffold protein SH3-do
Externí odkaz:
https://doaj.org/article/3f84a2e1c12a4e5f937947bcf7d93bed
Autor:
Yongqun He, Haihe Wang, Jie Zheng, Daniel P. Beiting, Anna Maria Masci, Hong Yu, Kaiyong Liu, Jianmin Wu, Jeffrey L. Curtis, Barry Smith, Alexander V. Alekseyenko, Jihad S. Obeid
Publikováno v:
Journal of Biomedical Semantics, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Host-microbiome interactions (HMIs) are critical for the modulation of biological processes and are associated with several diseases. Extensive HMI studies have generated large amounts of data. We propose that the logical represen
Externí odkaz:
https://doaj.org/article/f741cfba19274b27b9b0504b6bd064ff
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Alterations in the gut microbiome have been associated with various human diseases. Most existing gut microbiome studies stopped at the stage of identifying microbial alterations between diseased or healthy conditions. As inspired by reverse vaccinol
Externí odkaz:
https://doaj.org/article/d521c1e6fef14c9f9bbfa4d45129c604
Autor:
Wenliang Zhang, Shaoyang Zhang, Wen Guan, Zhicong Huang, Jianqiu Kong, Chunlong Huang, Haihe Wang, Shulan Yang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Accumulating evidence show that Poly C Binding Protein 1 (PCBP1) is deleted in distinct types of tumors as a novel tumor suppressor, but its tumor suppression mechanism remains elusive. Here, we firstly describe that downregulation of PCBP1 is signif
Externí odkaz:
https://doaj.org/article/f150099c3e484d629c3b778e338da70e
Autor:
Mingming Zhang, Yanli Wei, Yanbin Liu, Wen Guan, Xiaomei Zhang, Jianqiu Kong, Hui Li, Shulan Yang, Haihe Wang
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: Cancer stem cells (CSCs) are responsible for tumor initiation, chemoresistance, metastasis, and relapse, but the underlying molecular origin of CSCs remains elusive. Here we identified that metastatic phosphatase of regenerating liver 3 (PRL
Externí odkaz:
https://doaj.org/article/64568ffd16ff48e1bab5e7cb53349e47