Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Haihe Ruan"'
Autor:
Juan Yu, Chaoyang Xiong, Baowen Zhuo, Zengqi Wen, Jie Shen, Cuifang Liu, Luyuan Chang, Kehui Wang, Min Wang, Chenyi Wu, Xudong Wu, Xueqin Xu, Haihe Ruan, Guohong Li
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107953- (2020)
Summary: Chromatin dynamics play a critical role in cell fate determination and maintenance by regulating the expression of genes essential for development and differentiation. In mouse embryonic stem cells (mESCs), maintenance of pluripotency coinci
Externí odkaz:
https://doaj.org/article/535649a3840e43bc8bcee137095351da
Publikováno v:
Nucleic Acids Research
Nucleosome is the basic structural unit of chromatin, and its dynamics plays critical roles in the regulation of genome functions. However, how the nucleosome structure is regulated by histone variants in vivo is still largely uncharacterized. Here,
Autor:
Haihe Ruan, Xiaolin Bi, Ursula Adams, Li Tao, Yanglu Yang, Meng-Qiu Dong, Shengyi Peng, Songshu Meng, Zengqiang Yuan, Qi Xie, Tie-Mei Li
Publikováno v:
Journal of Biological Chemistry. 289:34205-34213
E2F1 and FOXO3 are two transcription factors that have been shown to participate in cellular senescence. Previous report reveals that E2F1 enhanced cellular senescence in human fibroblast cells, while FOXO transcription factors play against senescenc
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
Autor:
Resham L Gurung, Marzia Fumagalli, Anitha Suram, Utz Herbig, Fabrizio d'Adda di Fagagna, Raffaella Di Micco, Aurora Cerutti, Neena Mirani, Haihe Ruan, Priyanka L. Patel, Virginia Boccardi, Jessica Kaplunov, Manoor Prakash Hande
Publikováno v:
The EMBO Journal. 31:2839-2851
In normal human somatic cells, telomere dysfunction causes cellular senescence, a stable proliferative arrest with tumour suppressing properties. Whether telomere dysfunction-induced senescence (TDIS) suppresses cancer growth in humans, however, is u
Autor:
Haihe Ruan, Yuh-Hwa Wang
Publikováno v:
Journal of Molecular Biology. 383:292-300
Both chromatin structure and formation of triplex DNA at expanded GAA TTC repeats have been shown to regulate the FXN gene silencing, which causes Friedreich's ataxia. Recent studies have suggested that the presence of heterochromatin at the long exp
Autor:
Ting Yao, Junnan Fang, Zhouliang Yu, Guohong Li, Wenqiang Deng, Ping Chen, Rui-Ming Xu, Yun Wei, Haihe Ruan, Qinglong You, Li Huang, Yan Teng, Yuting Liu
Specific recognition of centromere-specific histone variant CENP-A-containing chromatin by CENP-N is an essential process in the assembly of the kinetochore complex at centromeres prior to mammalian cell division. However, the mechanisms of CENP-N re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aea1e7275304d4e125c5ef9668d14c5
https://europepmc.org/articles/PMC4441053/
https://europepmc.org/articles/PMC4441053/
Autor:
Haihe Ruan, Christopher E. Pearson, Yuh-Hwa Wang, Kerrie Nichol Edamura, Tohru Matsuura, Katharine A. Hagerman
Publikováno v:
Gene. 434(1-2)
Nucleosome packaging influences many aspects of DNA metabolism such as replication, repair and transcription, and via this link likely has further downstream effects on genome stability. The instability and expansion of repetitive sequences is associ
Autor:
Junnan Fang1,2, Yuting Liu1,2, Yun Wei1, Wenqiang Deng1,2, Zhouliang Yu1,2, Li Huang1, Yan Teng1, Ting Yao1, Qinglong You1,2, Haihe Ruan1, Ping Chen1, Rui-Ming Xu1, Guohong Li1 liguohong@sun5.ibp.ac.cn
Publikováno v:
Genes & Development. 2015, Vol. 29 Issue 10, p1058-1073. 16p.
Autor:
Qi Xie1, Shengyi Peng1,2, Li Tao1,3, Haihe Ruan1, Yanglu Yang1,2, Tie-Mei Li3, Adams, Ursula4, Songshu Meng5, Xiaolin Bi5, Meng-Qiu Dong3, Zengqiang Yuan1 zqyuan@sun5.ibp.ac.cn
Publikováno v:
Journal of Biological Chemistry. 12/5/2014, Vol. 289 Issue 49, p34205-34213. 9p.