Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Haiguo Sun"'
Autor:
Hongjian Qin, Zijian Han, Emmanuel Mintah Bonku, Haiguo Sun, Abdullajon Odilov, Fuqiang Zhu, Safomuddin Abduahadi, Weiliang Zhu, Jingshan Shen, Haji A. Aisa
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Amides are important intermediates in organic chemistry and the pharmaceutical industry, but their low reactivity requires catalysts and/or severe reaction conditions for esterification. Here, a novel approach was devised to convert amides i
Externí odkaz:
https://doaj.org/article/2d0296056171457d831e32f0f08b6e31
Publikováno v:
IBRO Neuroscience Reports, Vol 14, Iss , Pp 129-137 (2023)
Prior studies examining the effects of cocaine on the dynorphin/kappa opioid receptor (Dyn/KOR) system primarily focus on non-contingent cocaine exposure, but the effects of self-administration, which more closely reflects human drug-taking behaviors
Externí odkaz:
https://doaj.org/article/938a3f9a138a4c8497cbaea5aa21a894
Autor:
Yunping Hu, Haiguo Sun, Rick T. Owens, Zhennan Gu, Jansheng Wu, Yong Q. Chen, Joseph T. O'Flaherty, Iris J. Edwards
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 10, Pp 826-836 (2010)
Evidence indicates that diets enriched in n-3 polyunsaturated fatty acids (n-3 PUFAs) reduce the risk of prostate cancer, but biochemical mechanisms are unclear. Syndecan-1 (SDC-1), a transmembrane heparan sulfate proteoglycan, supports the integrity
Externí odkaz:
https://doaj.org/article/cd2c1cc3e26d4082bc3039a8fbd69a41
Autor:
Yunping Hu, Haiguo Sun, Rick T. Owens, Jiansheng Wu, Yong Q. Chen, Isabelle M. Berquin, Donna Perry, Joseph T. O'Flaherty, Iris J. Edwards
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 10, Pp 1042-1053 (2009)
Epidermal growth factor receptor (EGFR) and androgen receptor (AR) pathways play pivotal roles in prostate cancer progression. Therefore, agents with dual-targeting ability may have important therapeutic potential. Decorin, a proteoglycan present in
Externí odkaz:
https://doaj.org/article/ef65541785d046ef8f907e8c77f76205
Autor:
Joseph T O'Flaherty, Yungping Hu, Rhonda E Wooten, David A Horita, Michael P Samuel, Michael J Thomas, Haiguo Sun, Iris J Edwards
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45480 (2012)
A 15-LOX, it is proposed, suppresses the growth of prostate cancer in part by converting arachidonic, eicosatrienoic, and/or eicosapentaenoic acids to n-6 hydroxy metabolites. These metabolites inhibit the proliferation of PC3, LNCaP, and DU145 prost
Externí odkaz:
https://doaj.org/article/f38c19b8db4d4e26bfae1cf6f486c568
Autor:
Haiguo Sun, Yunping Hu, Zhennan Gu, Martha D Wilson, Yong Q Chen, Lawrence L Rudel, Mark C Willingham, Iris J Edwards
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20502 (2011)
Long chain n-3 PUFA have been shown to have chemopreventive properties against breast cancer through various mechanisms. One pathway, studied in human breast cancer cell lines, involves upregulation of the proteoglycan, syndecan-1 (SDC-1) by n-3 PUFA
Externí odkaz:
https://doaj.org/article/128990d2278f4808913ea17b9be9e06d
Autor:
Haiguo Sun, Mengyu Xi, Qiang Jin, Zhengdan Zhu, Yani Zhang, Guihua Jia, Guanghao Zhu, Mengru Sun, Hongwei Zhang, Xuelian Ren, Yong Zhang, Zhijian Xu, He Huang, Jingshan Shen, Bo Li, Guangbo Ge, Kaixian Chen, Weiliang Zhu
Publikováno v:
Journal of Medicinal Chemistry. 65:11840-11853
Site-selective lysine modification of peptides and proteins in aqueous solutions or in living cells is still a big challenge today. Here, we report a novel strategy to selectively quinolylate lysine residues of peptides and proteins under native cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acd1b9f0a6986c02fb999859863123a
https://doi.org/10.1021/acs.jmedchem.2c00937
https://doi.org/10.1021/acs.jmedchem.2c00937
Autor:
Anna Neel, James D. Miller, Shiyu Wang, Minghao Li, Jonathan C. Mayer, Haiguo Sun, Brian McCool, Rong Chen
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06c39d0c06a0a1edf81a1dbecdfa0bb3
https://doi.org/10.1124/jpet.122.254020
https://doi.org/10.1124/jpet.122.254020
Autor:
Paliarin, Franciely, Duplantis, Chelsea, Jones, Andrea F., Cucinello-Ragland, Jessica, Basavanhalli, Samhita, Blaze, Emily, Doré, Evan, Neel, Anna Isabella, Haiguo Sun, Rong Chen, Edwards, Scott, Gilpin, Nicholas W., Messing, Robert O., Maiya, Rajani
Publikováno v:
eNeuro; Jul2023, Vol. 10 Issue 7, p1-16, 16p
Autor:
Jinfeng Zhou, Hui Zhang, Ke Hu, Zhijian Xu, Yao Cheng, Jumei Shi, Kang Lu, Qilin Feng, Weiliang Zhu, Bo Li, Gege Chen, Xiaosong Wu, Ye Lu, Yingcong Wang, Liangning Hu, Lu Gao, Dongliang Song, Haiguo Sun
Publikováno v:
Cancer Letters. 478:45-55
Multiple myeloma (MM) is an incurable hematological malignancy, for which novel effective therapies are urgently needed. We synthesized a novel phosphoramide compound, DCZ0847, showing a potent anti-myeloma activity both in vitro and in vivo. DCZ0847
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebd9f5ba5798f87cb6080d6c6423139
https://doi.org/10.1016/j.canlet.2020.03.006
https://doi.org/10.1016/j.canlet.2020.03.006