Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Haigen Shen"'
Publikováno v:
Synlett. 31:41-44
The copper-catalyzed radical bis(trifluoromethylation) of alkynes and 1,3-enynes is described. With Cu(CH3CN)4BF4 as the catalyst, the reaction of arylalkynes with Togni reagent II and (bpy)Zn(CF3)2at room temperature affords the corresponding 1,2-bi
Publikováno v:
Chem. 5:940-949
Summary Direct trifluoromethylation of C(sp3)–H bonds, especially in late stages, remains a formidable challenge. Herein, we describe the copper-catalyzed benzylic C(sp3)–H trifluoromethylation. With Cu(I) or Cu(II) as the catalyst, (bpy)Zn(CF3)2
Publikováno v:
Angewandte Chemie International Edition. 58:2510-2513
Reported herein is an unprecedented protocol for trifluoromethylation of unactivated aliphatic C(sp3 )-H bonds. With Cu(OTf)2 as the catalyst, the reaction of N-fluoro-substituted carboxamides (or sulfonamides) with Zn(CF3 )2 complexes provides the c
Publikováno v:
Angewandte Chemie. 131:2532-2535
Publikováno v:
Organic Letters. 20:7062-7065
The copper-mediated C(sp2)-H trifluoromethylation of aldehydes is described. The reaction of aldehydes with (bpy)Cu(CF3)3, Et3SiH, and K2S2O8 in aqueous acetone at room temperature provides the corresponding trifluoromethyl ketones in satisfactory yi
Publikováno v:
Journal of the American Chemical Society. 141(29)
We report herein an unprecedented protocol for aminotrifluoromethylation of alkenes. With Cu(OTf)2 as the catalyst, the reaction of alkenes, (bpy)Zn(CF3)2, and N-fluorobis(benzenesulfonyl)imide (NFSI) at room temperature provides the corresponding am
Publikováno v:
Organic letters. 21(13)
The copper-catalyzed ring-opening C-trifluoromethylation of cycloalkanone oximes with Zn(CF3)2 complexes is described. The reaction proceeds in dichloromethane under mild conditions, providing an efficient and general entry to γ- or δ-CF3-substitut
Publikováno v:
Organic Letters. 19:698-701
The trifluoromethylalkynylation of unactivated alkenes with alkynyl sulfones and Togni's reagent was developed. The reaction was catalyzed by 2,4,6-trimethylpyridine, leading to various β-trifluoromethylated alkynes under metal-free conditions with
Publikováno v:
Angewandte Chemie (International ed. in English). 58(8)
Reported herein is an unprecedented protocol for trifluoromethylation of unactivated aliphatic C(sp
Publikováno v:
Organic letters. 20(22)
The copper-mediated C(sp