Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Haifei Gao"'
Autor:
Virginie Malard, Virginie Cendret, Florence Djedaïni-Pilard, Vincent Moreau, Marc François-Heude, Chantal Pichon, Patrick Midoux, François M. Lemoine, Véronique Mateo, Téo Gallego, Haifei Gao, Cristine Gonçalves
Publikováno v:
Carbohydrate Research
Carbohydrate Research, Elsevier, 2020, 487, pp.107877. ⟨10.1016/j.carres.2019.107877⟩
Carbohydrate Research, Elsevier, 2020, 487, pp.107877. ⟨10.1016/j.carres.2019.107877⟩
International audience; Mannose Receptor (MR) and DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) are two mannose-specific targets for antigens carried by liposomes but DC-SIGN is more specific of DCs. Here, DC targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f25dfed5b021c4ff04cfa7547e432a4
https://hal.archives-ouvertes.fr/hal-02522179/file/S0008621519305105.pdf
https://hal.archives-ouvertes.fr/hal-02522179/file/S0008621519305105.pdf
Autor:
Haifei Gao, Ludger Johannes, Jean-Claude Florent, Eva Y. Chi, Jaroslaw Majewski, Erik B. Watkins
Publikováno v:
Nano letters. 19(10)
Biomembranes are hard to compress laterally, and membrane area compressibility has not been associated with biological processes. Using X-ray surface scattering, we observed that bacterial Shiga toxin compresses lipid packing in a gel phase monolayer
Publikováno v:
International Journal of Pharmaceutics. 601:120566
Here, we report the synthesis of 3,6,9-trioxaundecan-1-{4-[(2-Chloroethyl)Ethylamino)]-Benzylamino},11-Azide (CEBA). CEBA alkylates the N7 of guanine of DNA thanks its chloroethyl group and can be coupled by a strain-promoted azide-alkyne cycloadditi
Autor:
Weria Pezeshkian, Senthil Arumugam, John Hjort Ipsen, Ludger Johannes, Ulrike Becken, Patricia Bassereau, Julian C. Shillcock, Haifei Gao, Jean-Claude Florent
Publikováno v:
ACS Nano
Pezeshkian, W, Gao, H, Arumugam, S, Becken, U, Bassereau, P, Florent, J C, Ipsen, J H, Johannes, L & Shillcock, J C 2017, ' Mechanism of Shiga Toxin Clustering on Membranes ', ACS Nano, vol. 11, no. 1, pp. 314-324 . https://doi.org/10.1021/acsnano.6b05706
Pezeshkian, W, Gao, H, Arumugam, S, Becken, U, Bassereau, P, Florent, J C, Ipsen, J H, Johannes, L & Shillcock, J C 2017, ' Mechanism of Shiga Toxin Clustering on Membranes ', ACS Nano, vol. 11, no. 1, pp. 314-324 . https://doi.org/10.1021/acsnano.6b05706
The bacterial Shiga toxin interacts with its cellular receptor, the glycosphingolipid globotriaosylceramide (Gb3 or CD77), as a first step to entering target cells. Previous studies have shown that toxin molecules cluster on the plasma membrane, desp
Autor:
Yan Niu, Guanyu Yang, Chao Wang, Fengrong Xu, Ping Xu, Lei Liang, Haifei Gao, Peng Liu, Qi Sun
Publikováno v:
Letters in Drug Design & Discovery. 10:297-302
Autor:
Paul-Alain Jaffrès, Loïc Lemiègre, Virginie Malard, Cristine Gonçalves, Julie Barbeau, Thierry Benvegnu, Haifei Gao, Allan Quelen, Chantal Pichon, Patrick Midoux, Mathieu Berchel
Publikováno v:
Carbohydrate Research
Carbohydrate Research, Elsevier, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩
Carbohydrate Research, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩
Carbohydrate Research, Elsevier, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩
Carbohydrate Research, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩
International audience; An archaeal diether lipid possessing a tri-antenna of α-D-mannopyranoside linked via an oligoethylene spacer to a (2S)-2-(phytanyloxy)-3-(hexadecyloxy)propanoic acid backbone (TriMan-Diether) was designed and synthesized. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323ad6e37d8c5fda837d9b8f4353e32c
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01398046
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01398046
Publikováno v:
Chemical Biology & Drug Design. 80:775-780
A series of 3, 5-disubstituted benzimidamides were synthesized and biologically evaluated as potential BACE1 inhibitors. Both the targeted compounds (benzimidamides) and the synthetic intermediates (benzonitriles) were tested for their BACE1 inhibito
Autor:
Chao Ma, Guanyu Yang, Hongwei Jin, Haifei Gao, Fengrong Xu, Peng Liu, Yongjian Li, Yan Niu, Chao Wang, Ping Xu
Publikováno v:
Chemical Biology & Drug Design. 79:972-980
This article describes the identification of two small molecular inhibitors for β-secretase by integrating virtual screening with fluorescence resonance energy transfer bioassay. A ligand-based pharmacophore model was developed, and the sequential v
Autor:
Jean-Claude Florent, Patricia Bassereau, John Hjort Ipsen, Weria Pezeshkian, Senthil Arumugam, Ludger Johannes, Haifei Gao, Julian C. Shillcock, Ulrike Becken
Publikováno v:
ACS Nano. 12:2079-2079
Autor:
Ludger Johannes, Thomas Arnold, Jean-Claude Florent, Nathalie Chopin, Haifei Gao, Bernd Struth, Erik B. Watkins, Andrew J. C. Dennison
Publikováno v:
Biophysical journal 107(5), 1146-1155 (2014). doi:10.1016/j.bpj.2014.07.023
Globotriaosylceramide (Gb3), a glycosphingolipid found in the plasma membrane of animal cells, is the endocytic receptor of the bacterial Shiga toxin. Using x-ray reflectivity (XR) and grazing incidence x-ray diffraction (GIXD), lipid monolayers cont