Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Haifa Hallaq"'
Autor:
Haifa Hallaq, Katherine T. Murray, Jennifer D. Kunic, Alfred L. George, Dao W. Wang, K. Sam Wells
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 302:H782-H789
Na+current derived from expression of the cardiac isoform SCN5A is reduced by receptor-mediated or direct activation of protein kinase C (PKC). Previous work has suggested a possible role for loss of Na+channels at the plasma membrane in this effect,
Autor:
Haifa Hallaq, M.D. Alexander Leaf
Publikováno v:
Nutrition Reviews. 50:402-406
Autor:
Koji Fukuda, Zhenjiang Yang, Jianxun Yi, Dao W. Wang, Prakash C. Viswanathan, K. Sam Wells, Katherine T. Murray, Haifa Hallaq, Jingsong Zhou, Wangzhen Shen
Publikováno v:
Cardiovascular Research. 72:250-261
Na(+) current derived from expression of the principal cardiac Na(+) channel, Na(v)1.5, is increased by activation of protein kinase A (PKA). This effect is blocked by inhibitors of cell membrane recycling, or removal of a cytoplasmic endoplasmic ret
Autor:
Clifford W. Bogue, James L. McGrath, Harris C. Jacobs, Emese Pinter, Martina Brueckner, Haifa Hallaq, Josephine Enciso, Hemaxi Vasavada, Xiaobing Jiang, Caroline J. Zeiss, Joseph A. Madri, Christine M. Wilson
Publikováno v:
Development. 131:5197-5209
The homeobox gene Hhex has recently been shown to be essential for normal liver, thyroid and forebrain development. Hhex–/– mice die by mid-gestation (E14.5) and the cause of their early demise remains unclear. Because Hhex is expressed in the de
Autor:
Harold A. Spurgeon, Salvatore Pepe, Alexander Leaf, Konstantin Y. Bogdanov, Haifa Hallaq, Edward G. Lakatta
Publikováno v:
Proceedings of the National Academy of Sciences. 91:8832-8836
The effect of docosahexaenoic acid (DHA; C22:6) on dihydropyridine (DHP) interaction with L-type Ca2+ channel current (ICa), cytosolic Ca2+ (Cai), and cell contraction in isolated adult rat cardiac myocytes was studied. The DHP L-type Ca(2+)-channel
Autor:
Zhenjiang Yang, Katherine T. Murray, Carrie F. Browning, Amy-Joan L. Ham, Matthew R Hall, Haifa Hallaq, Andrew J. Link, Meagan Jane Mcgrath, Christina Anne Mitchell, Jan Esker, Liudmila V. Yermalitskaya
Publikováno v:
Cardiovascular research. 78(3)
Aims Protein–protein interactions are critical for the normal membrane trafficking, localization, and function of voltage-gated ion channels. In human heart, the Shaker-related voltage-gated K+ channel KCNA5 α-subunit forms the major basis of an a
Publikováno v:
Proceedings of the National Academy of Sciences. 87:7834-7838
Isolated neonatal cardiac myocytes have been utilized as a model for the study of cardiac arrhythmogenic factors. The myocytes respond to the toxic effects of a potent cardiac glycoside, ouabain at 0.1 mM, by an increase in their spontaneous beating
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(10)
A specially prepared dog model of myocardial infarction was used to test the efficacy of the long-chain polyunsaturated fish oil omega 3 fatty acids eicosapentaenoic (20:5 n-3) and docosahexaenoic (22:6 n-3) acids to prevent ischemia-induced malignan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 89(5)
The highly unsaturated n-3 fatty acids from fish oils, eicosapentaenoic acid [EPA; C20:5 (n-3)] and docosahexanoic acid [DHA; C22:6 (n-3)], prevent the toxicity of high concentrations of the cardiac glycoside ouabain to isolated neonatal rat cardiac