Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Haider Inam"'
Autor:
Thu Nguyen-Anh Tran, Nathan B. Wikle, Emmy Albert, Haider Inam, Emily Strong, Karel Brinda, Scott M. Leighow, Fuhan Yang, Sajid Hossain, Justin R. Pritchard, Philip Chan, William P. Hanage, Ephraim M. Hanks, Maciej F. Boni
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background When three SARS-CoV-2 vaccines came to market in Europe and North America in the winter of 2020–2021, distribution networks were in a race against a major epidemiological wave of SARS-CoV-2 that began in autumn 2020. Rapid and o
Externí odkaz:
https://doaj.org/article/cb937e87c69747779b6d269f47db0b01
Autor:
Haider Inam, Ivan Sokirniy, Yiyun Rao, Anushka Shah, Farnaz Naeemikia, Edward O'Brien, Cheng Dong, David M. McCandlish, Justin R. Pritchard
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103343- (2021)
Summary: Genomic data can facilitate personalized treatment decisions by enabling therapeutic hypotheses in individual patients. Mutual exclusivity has been an empirically useful signal for identifying activating mutations that respond to single agen
Externí odkaz:
https://doaj.org/article/f98a7049c703493fbae9b06d38862432
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 3951-3963.e4 (2020)
Summary: Rationally designing drugs that last longer in the face of biological evolution is a critical objective of drug discovery. However, this goal is thwarted by the diversity and stochasticity of evolutionary trajectories that drive uncertainty
Externí odkaz:
https://doaj.org/article/4b1b504584ba4c028c270886dafe7cbd
Autor:
Nadkarni, Sanjay, Haider, Inam
Publikováno v:
Worldwide Hospitality and Tourism Themes, 2022, Vol. 14, Issue 6, pp. 572-578.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/WHATT-05-2022-0054
Autor:
Mickaël Marloye, Haider Inam, Connor J. Moore, Tyler R. Mertens, Aude Ingels, Marilin Koch, Michal O. Nowicki, Véronique Mathieu, Justin R. Pritchard, Samuel G. Awuah, Sean E. Lawler, Franck Meyer, François Dufrasne, Gilles Berger
Publikováno v:
Inorg Chem Front
We disclose novel amphiphilic ruthenium and osmium complexes that auto-assemble into nanomedicines with potent antiproliferative activity by inhibition of mitochondrial respiration. The self-assembling units were rationally designed from the [M(p-cym
Autor:
Maciej F. Boni, Emmy Albert, Fuhan Yang, Scott M. Leighow, Thu Nguyen Anh Tran, Philip A. Chan, William P. Hanage, Ephraim M. Hanks, Nathan B. Wikle, Karel Brinda, Emily R Strong, Justin R. Pritchard, Haider Inam, Sajid Hossain
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Background When three SARS-CoV-2 vaccines came to market in Europe and North America in the winter of 2020–2021, distribution networks were in a race against a major epidemiological wave of SARS-CoV-2 that began in autumn 2020. Rapid and optimized
Autor:
Mickaël Marloye, François Dufrasne, Vinciane Debaille, Michel Gelbcke, Connor J. Moore, Haider Inam, Justin R. Pritchard, Franck Meyer, Gilles Berger
Publikováno v:
JBIC. Journal of biological inorganic chemistry
Ruthenium (Ru) and osmium (Os) complexes are of sustained interest in cancer research and may be alternative to platinum-based therapy. We detail here three new series of ruthenium and osmium complexes, supported by physico-chemical characterizations
Autor:
Stephen J. Elledge, Kady A. Dennis, Haider Inam, Peter M. Bruno, Connor J. Moore, John Sheehe, Justin R. Pritchard, Mengrou Lu, Michael T. Hemann
Publikováno v:
Proc Natl Acad Sci U S A
Small molecules can affect many cellular processes. The disambiguation of these effects to identify the causative mechanisms of cell death is extremely challenging. This challenge impacts both clinical development and the interpretation of chemical g
Autor:
Thu Nguyen-Anh Tran, Nathan B Wikle, Fuhan Yang, Haider Inam, Scott Leighow, Bethany Gentilesco, Philip Chan, Emmy Albert, Emily R Strong, Justin R Pritchard, William P Hanage, Ephraim M Hanks, Forrest W. Crawford, Maciej F Boni
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
In emergency epidemic and pandemic settings, public health agencies need to be able to measure the population-level attack rate, defined as the total percentage of the population infected thus far. During vaccination campaigns in such settings, publi
Autor:
Anushka Shah, Edward P. O'Brien, Yiyun Rao, Haider Inam, Cheng Dong, Farnaz Naeemikia, David M. McCandlish, Justin R. Pritchard, Ivan Sokirniy
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103343-(2021)
iScience, Vol 24, Iss 11, Pp 103343-(2021)
Summary Genomic data can facilitate personalized treatment decisions by enabling therapeutic hypotheses in individual patients. Mutual exclusivity has been an empirically useful signal for identifying activating mutations that respond to single agent