Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Haichuan Duan"'
Publikováno v:
The FASEB Journal. 32
Publikováno v:
Drug Metabolism and Disposition. 43:1773-1780
Plasma membrane monoamine transporter (PMAT) is a major uptake-2 monoamine transporter that shares extensive substrate and inhibitor overlap with organic cation transporters 1–3 (OCT1–3). Currently, there are no PMAT-specific inhibitors available
Publikováno v:
CCWC
Smart life assistant starts from collecting every possible data about a user and makes intelligent use of such data to support user. SuperCaly easily organizes daily life around one of the most important personal tool: the calendar. SuperCaly extends
Publikováno v:
Journal of Biological Chemistry. 289:27055-27064
Drug-induced taste disturbance is a common adverse drug reaction often triggered by drug secretion into saliva. Very little is known regarding the molecular mechanisms underlying salivary gland transport of xenobiotics, and most drugs are assumed to
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 45(7)
Methamphetamine is one of the most abused illicit drugs with roughly 1.2 million users in the United States alone. A large portion of methamphetamine and its metabolites is eliminated by the kidney with renal clearance larger than glomerular filtrati
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 47(12)
1. Beta-carbolines are indole alkaloids with a wide range of pharmacological and toxicological activities. Beta-carbolines are structurally related to the neurotoxin 1-methyl-4-phenylpyridinium (MPP+), a known substrate of organic cation transporters
Autor:
Jinwoo Lee, Colin R. Jefcoate, Haichuan Duan, Ibrahim Musaitif, Yee Hoon Foong, Tiegang Tong, Takeshi Yamazaki
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Frontiers in Endocrinology
Frontiers in Endocrinology
The cholesterol transfer function of steroidogenic acute regulatory protein (StAR) is uniquely integrated into adrenal cells, with mRNA translation and protein kinase A (PKA) phosphorylation occurring at the mitochondrial outer membrane (OMM). The St
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 359(3)
Renal transporter-mediated drug-drug interactions (DDIs) are of significant clinical concern, as they can adversely impact drug disposition, efficacy, and toxicity. Emerging evidence suggests that human renal organic cation transporter 2 (hOCT2) and
Publikováno v:
Journal of chemical neuroanatomy.
Plasma membrane monoamine transporter (PMAT) is a newly discovered monoamine transporter belonging to the equilibrative nucleoside transporter family. Highly expressed in the brain, PMAT represents a major uptake2 transporter that may play a role in
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 339:376-385
Plasma membrane monoamine transporter (PMAT) is a new polyspecific transporter that interacts with a wide range of structurally diverse organic cations. To map the physicochemical descriptors of cationic compounds that allow interaction with PMAT, we