Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Haibin Mao"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Molecular glue has been used as a broad term describing a class of protein interaction-promoting compounds. Here, the authors outline two unifying thermodynamic features to formally define molecular glues and guide their prospective discovery.
Externí odkaz:
https://doaj.org/article/9c7caa35a13e48688aeee09088ea7811
Autor:
Sumeet K. Singh, Andres Reyna, Xiaowen Xie, Haibin Mao, Meihuan Ji, Ning Zheng, Peter L. Hsu, Champak Chatterjee
Publikováno v:
Chemical Communications. 59:4063-4066
An efficient total chemical synthesis of site-specifically sumoylated histone H4 revealed its negative biochemical crosstalk with histone H2B ubiquitylation in vitro and in human cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6965314bf3529319c210807067a58f3f
https://doi.org/10.1039/d2cc06683a
https://doi.org/10.1039/d2cc06683a
Autor:
Nargis Parvin Laha, Ricardo F H Giehl, Esther Riemer, Danye Qiu, Naga Jyothi Pullagurla, Robin Schneider, Yashika Walia Dhir, Ranjana Yadav, Yeshambel Emewodih Mihiret, Philipp Gaugler, Verena Gaugler, Haibin Mao, Ning Zheng, Nicolaus von Wirén, Adolfo Saiardi, Saikat Bhattacharjee, Henning J Jessen, Debabrata Laha, Gabriel Schaaf
Publikováno v:
Plant Physiology. 190:2722-2738
The combinatorial phosphorylation of myo-inositol results in the generation of different inositol phosphates (InsPs), of which phytic acid (InsP6) is the most abundant species in eukaryotes. InsP6 is also an important precursor of the higher phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfe353a5cd5d22c92b164f02b27c5e5
https://doi.org/10.1093/plphys/kiac425
https://doi.org/10.1093/plphys/kiac425
Autor:
Ru, Zhang, Yang, Liu, Wenjun, Wang, Yandong, Xu, Zuzhen, Wang, Huan, Zhong, Chenchen, Tang, Jing, Wang, Hongyang, Sun, Haibin, Mao, Jinpeng, Yan
Publikováno v:
Fish & Shellfish Immunology. 127:23-34
Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a crucial role in the Toll-like receptor/IL-1R signal pathway, which mediates the downstream signal transduction involved in innate and adaptive immunity. In the present study, an IRAK4 homolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d39b77afd7ad9c18d30c5277e22659
https://doi.org/10.1016/j.fsi.2022.05.056
https://doi.org/10.1016/j.fsi.2022.05.056
Autor:
Laha, Nargis Parvin, Giehl, Ricardo F. H., Riemer, Esther, Danye Qiu, Pullagurla, Naga Jyothi, Schneider, Robin, Yashika Walia Dhir, Yadav, Ranjana, Mihiret, Yeshambel Emewodih, Gaugler, Philipp, Gaugler, Verena, Haibin Mao, Ning Zheng, von Wirén, Nicolaus, Saiardi, Adolfo, Bhattacharjee, Saikat, Jessen, Henning J., Laha, Debabrata, Schaaf, Gabriel
Publikováno v:
Plant Physiology; Dec2022, Vol. 190 Issue 4, p2722-2738, 17p
Autor:
Gabriel Schaaf, Eva Maria Schaefer, Hitika Gulabani, Yashika Walia Dhir, Zhaleh Haghighat Shishavan, Philipp Gaugler, Nargis Parvin Laha, Debabrata Laha, Haibin Mao, Ricardo Fabiano Hettwer Giehl, Adolfo Saiardi, Saikat Bhattacharjee, Nicolaus von Wirén, Ning Zheng, Henning J. Jessen
The combinatorial phosphorylation ofmyo-inositolresults in the generation of different inositol phosphates (InsP), of which phytic acid (InsP6) is the most abundant species in eukaryotes. InsP6is also the precursor of higher phosphorylated forms call
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35e96eb8708e863901fe1f6bca6ced2
https://doi.org/10.1101/2020.04.23.058487
https://doi.org/10.1101/2020.04.23.058487
Autor:
Chuanlong Zang, Zhixue Xu, Xiayun Wei, Chuanzheng Zhou, Yan Ding, Xiaozhe Zhang, Ning Zheng, Hong Lin, Qiuyu Fu, Yang Su, Li Liu, Sining He, Xiaoli Yang, Feng Rao, Haibin Mao, Yasong Cui, Tao Wang, Niu Huang, Lilin Du, Yi Wei
Publikováno v:
Proc Natl Acad Sci U S A
The Cullin-RING ligases (CRLs) are the largest family of ubiquitin E3s activated by neddylation and regulated by the deneddylase COP9 signalosome (CSN). The inositol polyphosphate metabolites promote the formation of CRL–CSN complexes, but with unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221f4d64cf24c205875e883ce6165f62
https://pubmed.ncbi.nlm.nih.gov/32156730
https://pubmed.ncbi.nlm.nih.gov/32156730
Autor:
Ignacia Echeverria, Sarah A. Block, Lan Huang, Ning Zheng, Andrej Sali, Ilan E. Chemmama, Scott D. Rychnovsky, Clinton Yu, Craig B. Gutierrez, Haibin Mao
Publikováno v:
Proc Natl Acad Sci U S A
The COP9 signalosome (CSN) is an evolutionarily conserved eight-subunit (CSN1–8) protein complex that controls protein ubiquitination by deneddylating Cullin-RING E3 ligases (CRLs). The activation and function of CSN hinges on its structural dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3134808c938db391e7f2dc8d22b7c3c6
https://pubmed.ncbi.nlm.nih.gov/32034103
https://pubmed.ncbi.nlm.nih.gov/32034103
Autor:
Craig Gutierrez, Ilan E. Chemmama, Haibin Mao, Clinton Yu, Ignacia Echeverria, Sarah Block, Scott D. Rychnovsky, Ning Zheng, Andrej Sali, Lan Huang
This repository contains the modeling files and the analysis related to the article "Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling"C.Gutierrez*,I.E.Chemmama*,et al.Proceedings o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557c822582e0d630e880450ca69806a2
Autor:
Thomas R. Hinds, Fabrizio Ticchiarelli, Ottoline Leyser, Ning Zheng, Nitzan Shabek, Haibin Mao
Publikováno v:
Nature
Nature, vol 563, iss 7733
Nature, vol 563, iss 7733
The strigolactones, a class of plant hormones, regulate many aspects of plant physiology. In the inhibition of shoot branching, the α/β hydrolase D14-which metabolizes strigolactone-interacts with the F-box protein D3 to ubiquitinate and degrade th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202e0f655eff7b57951ef9622e214af4
http://europepmc.org/articles/PMC6265067
http://europepmc.org/articles/PMC6265067