Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Haibao Shang"'
Autor:
Jue Wang, Wen Zheng, Shuquan Zheng, Ye Yuan, Wei Wen, Weiyi Cui, Lifang Xue, Xueting Sun, Haibao Shang, Hongyan Zhang, Rui-Ping Xiao, Shan Gao, Xiuqin Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 68-77 (2023)
Angiopoietin-like protein 3 (ANGPTL3) is an important regulator of lipoproteins by inhibiting both lipoprotein and endothelial lipases. It has been intensively investigated as a drug target for the treatment of dyslipidemia. In the present study, a m
Externí odkaz:
https://doaj.org/article/d61838593eed4ab0953d2fb0db6b93ed
Autor:
Xiaohai Zhou, Chenyang Zhang, Xueying Wu, Xinli Hu, Yan Zhang, Xuelian Wang, Lixia Zheng, Peng Gao, Jianyong Du, Wen Zheng, Haibao Shang, Keping Hu, Zhengfan Jiang, Yu Nie, Shengshou Hu, Rui-Ping Xiao, Xiaojun Zhu, Jing-Wei Xiong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Dusp6, an ERK specific phosphatase, was identified as a regenerative repressor during zebrafish heart regeneration. Here, the authors show that Dusp6 deficiency improves post infarctional cardiac repair by predominantly attenuating neutrophil-mediate
Externí odkaz:
https://doaj.org/article/52019d9b29114e4d8bfd914f95194350
Autor:
Mao Zhang, Junxia Zhang, Wenjia Zhang, Qingmei Hu, Li Jin, Peng Xie, Wen Zheng, Haibao Shang, Yan Zhang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Heart failure is a syndrome in which the heart cannot pump enough blood to meet the body's needs, resulting from impaired ventricular filling or ejection of blood. Heart failure is still a global public health problem and remains a substantial unmet
Externí odkaz:
https://doaj.org/article/610462c3e8024b65a8ef5cb679f3fc2a
Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys
Autor:
Wen Zheng, Yuli Liu, Haibao Shang, Yan Zhang, Dongwei Ma, Ning Hou, Jue Wang, Xueting Sun, Ying Peng, Lin Pan, Zhilong Wang, Xinran Tang, Rui-Ping Xiao, Xiuqin Zhang
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a global epidemic afflicting 20–30% in the general population. The animal model of NAFLD available at the present are less clinically relevant. In this study. We aimed to establish a
Externí odkaz:
https://doaj.org/article/ad5dd20963db45d08650576f2b8775d6
Autor:
Yao Xiao, Can Wang, Jia-Yu Chen, Fujian Lu, Jue Wang, Ning Hou, Xiaomin Hu, Fanxin Zeng, Dongwei Ma, Xueting Sun, Yi Ding, Yan Zhang, Wen Zheng, Yuli Liu, Haibao Shang, Wenzhen Zhu, Chensheng Han, Yulin Zhang, Kunfu Ouyang, Liangyi Chen, Ju Chen, Rui-Ping Xiao, Chuan-Yun Li, Xiuqin Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Hyperinsulinemia can precede the development of insulin resistance. Here the authors identify a PKD2 mutation that leads to hyperinsulinemia and insulin resistance in Rhesus monkey and show that PKD2 deficiency promotes beta cell insulin secretion by
Externí odkaz:
https://doaj.org/article/cbdb7808618149698d196802ee3bf15d
Autor:
Junxia Zhang, Ruqi Liang, Kai Wang, Wenjia Zhang, Mao Zhang, Li Jin, Peng Xie, Wen Zheng, Haibao Shang, Qingmei Hu, Jiayi Li, Gengjia Chen, Fujian Wu, Feng Lan, Lipeng Wang, Shi-Qiang Wang, Yongfeng Li, Yong Zhang, Jinghao Liu, Fengxiang Lv, Xinli Hu, Rui-Ping Xiao, Xiaoguang Lei, Yan Zhang
Publikováno v:
Circulation. 145:1154-1168
Background: Cardiac ischemia/reperfusion (I/R) injury has emerged as an important therapeutic target for ischemic heart disease, the leading cause of morbidity and mortality worldwide. At present, there is no effective therapy for reducing cardiac I/
Autor:
Jue, Wang, Wen, Zheng, Shuquan, Zheng, Ye, Yuan, Wei, Wen, Weiyi, Cui, Lifang, Xue, Xueting, Sun, Haibao, Shang, Hongyan, Zhang, Rui-Ping, Xiao, Shan, Gao, Xiuqin, Zhang
Publikováno v:
Molecular therapy. Nucleic acids. 31
Angiopoietin-like protein 3 (ANGPTL3) is an important regulator of lipoproteins by inhibiting both lipoprotein and endothelial lipases. It has been intensively investigated as a drug target for the treatment of dyslipidemia. In the present study, a m
Autor:
Yuan Yao, Fan Li, Mao Zhang, Li Jin, Peng Xie, Dairu Liu, Junxia Zhang, Xinli Hu, Fengxiang Lv, Haibao Shang, Wen Zheng, Xueting Sun, Jiaxin Duanmu, Fujian Wu, Feng Lan, Rui-Ping Xiao, Yan Zhang
Publikováno v:
Circ Res
Background: CaMKII (Ca 2+ /calmodulin-dependent kinase II) plays a central role in cardiac ischemia/reperfusion (I/R) injury—an important therapeutic target for ischemic heart disease. In the heart, CaMKII-δ is the predominant isoform and further
Autor:
Xueting Sun, Yao Xiao, Can Wang, Xiuqin Zhang, Zhimin Wang, Ning Hou, Yumei Li, Ye Yuan, Wen Zheng, Weiyi Cui, Zezhong Li, Yan Zhang, Jue Wang, Huiping Shi, Haibao Shang, Rui-Ping Xiao, Chuan-Yun Li, Dongwei Ma, Yuli Liu, Fanxin Zeng, Wei Wen
Publikováno v:
Journal of Molecular and Cellular Cardiology. 125:50-60
Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by destructive polyarthritis and systemic complications. It increases cardiovascular morbidity and mortality. However, the mechanism underlying RA-related cardiac damage remai
Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys
Autor:
Ying Peng, Yuli Liu, Dongwei Ma, Yan Zhang, Xiuqin Zhang, Xinran Tang, Jue Wang, Ning Hou, Zhilong Wang, Wen Zheng, Rui-Ping Xiao, Lin Pan, Haibao Shang, Xueting Sun
Publikováno v:
Diabetology & Metabolic Syndrome
Diabetology & Metabolic Syndrome, Vol 10, Iss 1, Pp 1-10 (2018)
Diabetology & Metabolic Syndrome, Vol 10, Iss 1, Pp 1-10 (2018)
Background Non-alcoholic fatty liver disease (NAFLD) is a global epidemic afflicting 20–30% in the general population. The animal model of NAFLD available at the present are less clinically relevant. In this study. We aimed to establish a NAFLD mod