Zobrazeno 1 - 10
of 57
pro vyhledávání: '"HaiSu Wan"'
Autor:
Senlin Yin, Keying Lu, Tao Tan, Jie Tang, Jingkuan Wei, Xu Liu, Xinlei Hu, Haisu Wan, Wei Huang, Yong Fan, Dan Xie, Yang Yu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Non-human primates share many features with humans and are an important animal model in neuroscience. Here, the authors present a comprehensive transcriptomic and open chromatin atlas of the rhesus macaque brain.
Externí odkaz:
https://doaj.org/article/6147a42a6f784b2a96238a771b8f2ce9
Autor:
Yong Cao, Xiaoyan Wang, Li Tang, Yan Li, Xueqin Song, Xu Liu, Mingying Li, Feng Chen, Haisu Wan
Publikováno v:
PeerJ, Vol 8, p e8662 (2020)
Background A number of homeobox genes have been implicated in the development of various cancers. However, the role of engrailed 2 (EN2), a member of the homeobox gene superfamily, in esophageal squamous cell carcinoma (ESCC) remains unknown. Methods
Externí odkaz:
https://doaj.org/article/28732d9a03054116a4ee1ad3bfc5bc1b
Autor:
Yingcheng Yang, Xiaoping Tang, Xueqin Song, Li Tang, Yong Cao, Xu Liu, Xiaoyan Wang, Yan Li, Minglan Yu, Haisu Wan, Feng Chen
Publikováno v:
PeerJ, Vol 7, p e6629 (2019)
Background Identification of specific biomarkers is important for the diagnosis and treatment of non-small cell lung cancer (NSCLC). HOXC6 is a homeodomain-containing transcription factor that is highly expressed in several human cancers; however, it
Externí odkaz:
https://doaj.org/article/027d8c871c9840a78949d9b1a80128a5
Autor:
Li Tang, Yong Cao, Xueqin Song, Xiaoyan Wang, Yan Li, Minglan Yu, Mingying Li, Xu Liu, Fang Huang, Feng Chen, Haisu Wan
Publikováno v:
PeerJ, Vol 7, p e6607 (2019)
Background HOXC6 is a member of the HOX gene family. The elevated expression of this gene occurs in prostate and breast cancers. However, the role of HOXC6 in esophageal squamous cell carcinoma (ESCC) remains largely uninvestigated. Methods The expre
Externí odkaz:
https://doaj.org/article/dbb183de157142999f896e5155ec29f4
Publikováno v:
Chinese Journal of Lung Cancer, Vol 18, Iss 1, Pp 55-58 (2015)
Octamer-binding transcription factor 4 (OCT4) belongs to the POU-homeodomain family of transcription factors and binds to an octamer motif, ATGCAAAT. OCT4 is the key transcription factor that is involved in the maintenance of pluripotency and self-re
Externí odkaz:
https://doaj.org/article/d069285f257347539364a7ca318f3a23
Publikováno v:
Chinese Journal of Lung Cancer, Vol 17, Iss 12, Pp 870-876 (2014)
Lentiviral vectors are currently very effective tools in molecular and cell experiment. Lentiviral vector, a kind of retroviral vectors, has a number of unique advantages in target gene transferation, for example, the ability of transfection to the d
Externí odkaz:
https://doaj.org/article/3b98c6a2b9664ed0930b6a4aa3960a7e
Publikováno v:
Chinese Journal of Lung Cancer, Vol 17, Iss 7, Pp 563-568 (2014)
Background and objective In vitro site-directed mutagenesis is a routine technique in molecular biology labs. However, although there are numbers of related methods available, most of these methods are not suitable for introducing mutations into larg
Externí odkaz:
https://doaj.org/article/f4fe5cff795e4b2a9bd0b18b7d828d81
Publikováno v:
Chinese Journal of Lung Cancer, Vol 17, Iss 6, Pp 469-473 (2014)
Background and objective The methods for introducing point mutations into target genes are important for dissecting the relationship of gene structure and function. Up to date, there are numbers of protocols available for the purpose. However, many o
Externí odkaz:
https://doaj.org/article/f8446799c60b44f3bc9618c0e43d3e4a
Publikováno v:
Chinese Journal of Lung Cancer, Vol 13, Iss 8, Pp 763-768 (2010)
Background and objective Invasion and metastasis is one of malignant phenotype of lung cancer and the important cause of the death of lung cancer patients. The aim of this study is to explore the methylation profile difference in different metastatic
Externí odkaz:
https://doaj.org/article/f99b455dfb2144b5be613d505d6abde3
Publikováno v:
Chinese Journal of Lung Cancer, Vol 13, Iss 5, Pp 506-510 (2010)
Background and objective Glutathione S-transferase M1 (GSTM1) is an important phase II metabolic enzyme gene which involves metabolism of various carcinogens in human body. Many studies showed that GSTM1 genetic polymorphism was associated with lung
Externí odkaz:
https://doaj.org/article/1d666360b7d54b649d4f8443c27051bd