Toxoplasma gondii ROP17 inhibits the innate immune response of HEK293T cells to promote its survival

Autor: Jie-Xi Li, Hai-Kuo Yan, Xing-Quan Zhu, Dan Chen, Hany M. Elsheikha, Bin-Tao Zhai, Jun-Jun He

Publikováno v: Parasitology Research. 118:783-792

Toxoplasma gondii secretes a group of rhoptry-secreted kinases (ROPs), which play significant roles in promoting intracellular infection. T. gondii rhoptry organelle protein 17 (ROP17) is one of these important effector proteins. However, its role in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc12a7c411ac815f64d9c6d60b05fb4
https://doi.org/10.1007/s00436-019-06215-y

Tissue distribution of deoxynivalenol in piglets following intravenous administration

Autor: Xianhui Huang, Huan-zhong Din, Zhenling Zeng, Pei-cheng Lu, Wei-cheng Li, Hai-kuo Yan, Deng Xianbai, Yong-jiang Ma, Xiao-long Fan

Publikováno v: Journal of Integrative Agriculture, Vol 14, Iss 10, Pp 2058-2064 (2015)

Contamination of deoxynivalenol (DON) in grains is common worldwide and pigs are particularly susceptible to this mycotoxin. The distribution of DON in porcine tissues following intravenous administration was investigated in this study. Fifteen pigs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed11c1ceea991fb3ea9798bf6cb17f90
https://doi.org/10.1016/s2095-3119(14)60942-4

Vaccination with a DNA Vaccine Coding for Perforin-Like Protein 1 and MIC6 Induces Significant Protective Immunity against Toxoplasma gondii

Autor: Yang Zhou, Gui-Lian Yang, Hai-Kuo Yan, Eskild Petersen, Hao-Xin Li, Rui-Qing Lin, Hui-Qun Song, Dong-Hui Zhou, Xing-Quan Zhu, Di Ren, Zi-Guo Yuan

Publikováno v: Yan, H-K, Yuan, Z-G, Song, H-Q, Petersen, E, Zhou, Y, Ren, D, Zhou, D-H, Li, H-X, Lin, R-Q, Yang, G-L & Zhu, X-Q 2012, ' Vaccination with a DNA vaccine coding for perforin-like protein 1 and MIC6 induces significant protective immunity against Toxoplasma gondii ', Clinical and Vaccine Immunology (Online), vol. 19, no. 5, pp. 684-9 . https://doi.org/10.1128/CVI.05578-11

Host cell invasion byToxoplasma gondiiis tightly related to microneme protein 6 (MIC6) andT. gondiiperforin-like protein 1 (TgPLP1). In this study, we constructed a DNA vaccine expressing a TgPLP1/MIC6 fusion protein using the pIRESneo vector, and we

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https://doi.org/10.1128/cvi.05578-11

Genetic variation among Clonorchis sinensis isolates from different geographic regions in China revealed by sequence analyses of four mitochondrial genes

Autor: Guiling Liu, F. C. Zou, Hui-Qun Song, Xing-Quang Zhu, Zi-Guo Yuan, R. Q. Lin, X.Q. Cai, Hai-Kuo Yan, B. Li, Juan Li, D.H. Zhou

Publikováno v: Journal of helminthology. 86(4)

The present study examined sequence variation in four mitochondrial (mt) genes, namely cytochrome c oxidase subunits 1 (cox1) and 2 (cox2), and NADH dehydrogenase subunits 1 and 2 (nad1 and nad2) among Clonorchis sinensis isolates from different ende

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https://pubmed.ncbi.nlm.nih.gov/22152452

Toxoplasma gondii: protective immunity against experimental toxoplasmosis induced by a DNA vaccine encoding the perforin-like protein 1

Autor: Min-Jun Xu, Zi-Guo Yuan, Xiu-Ling Zhong, Hai-Kuo Yan, Xiu-Xiang Zhang, Xing-Quan Zhu, Eskild Petersen, Xu-Li Chen, Dong-Hui Zhou, Rui-Qing Lin, Yong He, Quan Liu

Publikováno v: Yan, H-K, Yuan, Z-G, Petersen, E, Zhang, X-X, Zhou, D-H, Liu, Q, He, Y, Lin, R-Q, Xu, M-J, Chen, X-L, Zhong, X-L & Zhu, X-Q 2011, ' Toxoplasma gondii: protective immunity against experimental toxoplasmosis induced by a DNA vaccine encoding the perforin-like protein 1 ', Experimental Parasitology, vol. 128, no. 1, pp. 38-43 . https://doi.org/10.1016/j.exppara.2011.02.005

Toxoplasma gondii is an important zoonotic parasite infecting about one third of the world population, causing congenital infections and eye disease. T. gondii perforin-like protein 1 (TgPLP1) is believed to be involved in the acute virulence of T. g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f9c95d567f5ee40bd550a345de1ce4
https://pure.au.dk/portal/da/publications/toxoplasma-gondii-protective-immunity-against-experimental-toxoplasmosis-induced-by-a-dna-vaccine-encoding-the-perforinlike-protein-1(ab9e2bee-24b8-4c30-8109-0477a8dd2975).html