Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Hai-Shu Lin"'
Autor:
Kefa Li, Yanhong Luo, Weiwei Hu, Jinjin Yang, Danting Zhang, Huan Wei, Tingting You, Hai-Shu Lin, Zhihe Kuang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6764 (2024)
The SPRY domain-containing SOCS box proteins SPSB1, SPSB2, and SPSB4 utilize their SPRY/B30.2 domain to interact with a short region in the N-terminus of inducible nitric oxide synthase (iNOS), and recruit an E3 ubiquitin ligase complex to polyubiqui
Externí odkaz:
https://doaj.org/article/fe81faeafd3d40f8a89ab1b896a3564c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7083 (2022)
The immediate and delayed metabolic changes in rats treated with valproate (VPA), a drug used for the treatment of epilepsy, were profiled. An established approach using dried blood spots (DBS) as sample matrices for gas chromatography/mass spectrome
Externí odkaz:
https://doaj.org/article/1547609ea3bb4a15beda6723a5b0a2be
Autor:
Qingfeng He, Fengjiao Bu, Qizhen Wang, Min Li, Jiaying Lin, Zhijia Tang, Wen Yao Mak, Xiaomei Zhuang, Xiao Zhu, Hai-Shu Lin, Xiaoqiang Xiang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4485 (2022)
Schizandrol A (SZA) and schizandrol B (SZB) are two active ingredients of Wuzhi capsule (WZC), a Chinese proprietary medicine commonly prescribed to alleviate tacrolimus (FK-506)-induced hepatoxicity in China. Due to their inhibitory effects on cytoc
Externí odkaz:
https://doaj.org/article/a7002d6ee7a24e6ca985394595a841f1
Autor:
Min Li, Qingfeng He, Li Yao, Xiaofeng Wang, Zhijia Tang, Xiao Zhu, Hai-Shu Lin, Xiaoqiang Xiang
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1194 (2021)
Propylthiouracil (PTU) is commonly prescribed for the management of hyperthyroidism and thyrotoxicosis. Although the exact mechanism of action is not fully understood, PTU is associated with hepatoxicity in pediatric population. Glucuronidation media
Externí odkaz:
https://doaj.org/article/a8d10f0df6d343ab9a5a1a043188ee4c
Autor:
Lei Li, Haisheng He, Sifang Jiang, Jianping Qi, Yi Lu, Ning Ding, Hai-Shu Lin, Wei Wu, Xiaoqiang Xiang
Publikováno v:
Molecules, Vol 26, Iss 5, p 1271 (2021)
The application of physiologically based pharmacokinetic models to nanoparticles is still very restricted and challenging, owing to the complicated in vivo transport mechanisms involving nanoparticles, including phagocytosis, enhanced permeability an
Externí odkaz:
https://doaj.org/article/6777dfb550094769ba396db4f9e85e66
Autor:
Qingfeng He, Fengjiao Bu, Hongyan Zhang, Qizhen Wang, Zhijia Tang, Jing Yuan, Hai-Shu Lin, Xiaoqiang Xiang
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 198 (2021)
Wuzhi capsule (WZC) is commonly prescribed with tacrolimus in China to ease drug-induced hepatotoxicity. Two abundant active ingredients, schisantherin A (STA) and schisandrin A (SIA) are known to inhibit CYP3A enzymes and increase tacrolimus’s exp
Externí odkaz:
https://doaj.org/article/21e56a8aaf6142c88c6dcf8b026a692b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1141 (2021)
Artemether, an artemisinin derivative, is used in the management of life-threatening severe malaria. This study aimed to develop an intravenous dosage form of artemether using nanotechnology. Artemether-loaded zein nanoparticles were prepared by modi
Externí odkaz:
https://doaj.org/article/027ae1e996134db9a3a86cc1a816928a
Publikováno v:
Journal of Functional Foods, Vol 22, Iss , Pp 122-131 (2016)
To evaluate the potential of oxyresveratrol (OXY), a dietary polyphenol with various health-promoting activities as a nutraceutical/functional food ingredient, its absolute oral bioavailability (F) was examined in Sprague-Dawley rats. Upon single int
Externí odkaz:
https://doaj.org/article/d0ba337a92a14440a52a9360e8bd1b50
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Isorhapontigenin (trans–3,5,4′-trihydroxy–3′–methoxystilbene, ISO), a dietary resveratrol (trans–3,5,4′–trihydroxystilbene) derivative, possesses various health-promoting activities. To further evaluate its medicinal poten
Externí odkaz:
https://doaj.org/article/92bd06422ad14508b505789345482da1
Publikováno v:
Journal of Functional Foods, Vol 11, Iss , Pp 352-362 (2014)
This study aimed to evaluate the suitability of pterostilbene for anti-inflammatory application. The in vitro anti-inflammatory activities of pterostilbene were assessed using resveratrol, piceatannol and resveratrol trimethyl ether as comparators wh
Externí odkaz:
https://doaj.org/article/a9212240eba841ec96a14a5a96e4b354