Zobrazeno 1 - 10
of 1 096
pro vyhledávání: '"Hai SONG"'
Autor:
Ying Jin, Yuefeng Wu, Alexandre Reuben, Liang Zhu, Carl M. Gay, Qingzhe Wu, Xintong Zhou, Haomin Mo, Qi Zheng, Junyu Ren, Zhaoyuan Fang, Teng Peng, Nan Wang, Liang Ma, Lungevity PANSHI Initiative Consortium, Yun Fan, Hai Song, Jianjun Zhang, Ming Chen
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Small cell lung cancer (SCLC) is an aggressive pulmonary neuroendocrine malignancy featured by cold tumor immune microenvironment (TIME), limited benefit from immunotherapy, and poor survival. The spatial heterogeneity of TIME significantly
Externí odkaz:
https://doaj.org/article/13c7204465ef49f6b7c5296892d33b0a
Autor:
Huan Deng, Yamei Chen, Li Wang, Yibi Zhang, Qingqing Hang, Peijing Li, Peng Zhang, Jing Ji, Hai Song, Ming Chen, Ying Jin
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Our previous study revealed that PI3K/AKT/mTOR signaling was associated with SCLC radioresistance. SBC2 cells were used as primary radioresistance models, while H446 cells were continuously exposed to ionizing radiation (IR) to develop acqui
Externí odkaz:
https://doaj.org/article/4edf5f8e8c5f43feb1808681c2688a7a
Autor:
Ailing Wu, Zhongyue Li, Yilong Wang, Yi Chen, Jinkai Peng, Mengying Zhu, Yueyue Li, Hai Song, Dongming Zhou, Chudi Zhang, Yao Lv, Zhengyan Zhao
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Oncolytic viruses have recently been proven to be an effective and promising cancer therapeutic strategy, but there is rare data about oncolytic therapy in esophageal squamous cell carcinoma (ESCC), especially oncolytic measles virotherapy.
Externí odkaz:
https://doaj.org/article/7bfedc5c205a4432bcc21444cf0834bc
Publikováno v:
Advanced Intelligent Systems, Vol 5, Iss 6, Pp n/a-n/a (2023)
Histopathology is a critical approach for diagnostic tasks and precision treatment. However, histopathological deep learning tools for auto‐identification remain poorly developed. Meanwhile, the interpretation of the computer vision attention into
Externí odkaz:
https://doaj.org/article/44e07553afbc479f9450f029b247d8a4
Autor:
Yonggang Zou, Qi Zheng, Bin Jiang, Yuning Liu, Yanhua Xu, Liang Ma, Zonghao Hu, Ming Wu, Hai Song
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-13 (2022)
Abstract Necroptotic cell death is mediated by a super-molecular complex called necrosome which consists of receptor-interacting protein kinase 1 and 3 (RIPK1, RIPK3) and mixed-lineage kinase domain-like protein (MLKL). The role of these kinases has
Externí odkaz:
https://doaj.org/article/2a64ce600bee4535b519160110c8d9bb
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundTo provide a reference for hospital drug selection and rational clinical drug selection based on the evaluation of the safety, nutritional quality, and economy of 27 manufacturers of five varieties (18AA, 18AA-I, 18AA-II, 18AA-IV, 18AA-V) o
Externí odkaz:
https://doaj.org/article/319202af89ea4699a461a9f89b8c3ed8
Publikováno v:
工程科学学报, Vol 42, Iss 7, Pp 862-868 (2020)
Due to moisture in the ore, auxiliary material, and ladle refractory material, the hydrogen element is easily enriched in molten steel. In the metallurgy process, some hydrogen atoms form bubbles and are removed by gravity, whearas others solidify in
Externí odkaz:
https://doaj.org/article/ad565972e9384a6db7feedbe5e677ced
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. Overexpression or activation of epidermal growth factor receptor (EGFR) occurs commonly in multiple human cancers and promotes tumorigenesis. However, the underlying molecula
Externí odkaz:
https://doaj.org/article/95c37b4a35fe473c86704f8fc5cc3fea
Autor:
Ruyuan Zhou, Qirou Wu, Mengqiu Wang, Seema Irani, Xiao Li, Qian Zhang, Fansen Meng, Shengduo Liu, Fei Zhang, Liming Wu, Xia Lin, Xiaojian Wang, Jian Zou, Hai Song, Jun Qin, Tingbo Liang, Xin-Hua Feng, Yan Jessie Zhang, Pinglong Xu
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001122 (2021)
The Hippo-YAP pathway responds to diverse environmental cues to manage tissue homeostasis, organ regeneration, tumorigenesis, and immunity. However, how phosphatase(s) directly target Yes-associated protein (YAP) and determine its physiological activ
Externí odkaz:
https://doaj.org/article/1c1a795a50ae4782ad49dfdef46b4e3e
Autor:
Qi Zheng, Yonggang Zou, Peng Teng, Zhenghua Chen, Yuefeng Wu, Xiaoyi Dai, Xiya Li, Zonghao Hu, Shengjun Wu, Yanhua Xu, Weiguo Zou, Hai Song, Liang Ma
Publikováno v:
Cells, Vol 11, Iss 14, p 2191 (2022)
Shear stress exerted by the blood stream modulates endothelial functions through altering gene expression. KLF2 and KLF4, the mechanosensitive transcription factors, are promoted by laminar flow to maintain endothelial homeostasis. However, how the e
Externí odkaz:
https://doaj.org/article/8a967e5132734153a0a6469bad16331d