Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Hai Ning Shi"'
Publikováno v:
FEBS Open Bio, Vol 11, Iss 5, Pp 1476-1486 (2021)
NADPH oxidase (NOX) is a membrane‐bound enzyme complex that generates reactive oxygen species (ROS). Mutations in NOX subunit genes have been implicated in the pathogenesis of inflammatory bowel disease (IBD), indicating a crucial role for ROS in r
Externí odkaz:
https://doaj.org/article/0951ea51226a42aaaa2beeb8225a1ee0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Food allergies and other immune-mediated diseases have become serious health concerns amongst infants and children in developed and developing countries. The absence of available cures limits disease management to allergen avoidance and symptomatic t
Externí odkaz:
https://doaj.org/article/6519f8c524f443b0b09405e694f95b8b
Autor:
Chien Wen Su, Chih-Yu Chen, Lefei Jiao, Shao Rong Long, Tangyou Mao, Qiaorong Ji, Shane O’Donnell, Catherine Stanton, Shasha Zheng, W. Allan Walker, Bobby J. Cherayil, Hai Ning Shi
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 763-778 (2020)
Background & Aims: Epidemiological and animal studies have indicated an inverse correlation between the rising prevalence of obesity and metabolic syndrome and exposure to helminths. Whether helminth-induced immune response contributes to microbiota
Externí odkaz:
https://doaj.org/article/01e98e3d5c2846b5853a9c651ae97299
Autor:
Tangyou Mao, Chien-Wen Su, Qiaorong Ji, Chih-Yu Chen, Rongjun Wang, Deepak Vijaya Kumar, Jinggang Lan, Lefei Jiao, Hai Ning Shi
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Hyaluronan is a glycosaminoglycan polymer that has been shown to play an important role in homeostasis of the gastrointestinal tract. However, its mechanistic significance in gastrointestinal epithelial barrier elements remain unexplored. Here, our r
Externí odkaz:
https://doaj.org/article/78e7708c6b1c4eb5bbfa8ea08107b48e
Autor:
Jaime Belkind-Gerson, Hannah K. Graham, Justin Reynolds, Ryo Hotta, Nandor Nagy, Lily Cheng, Michal Kamionek, Hai Ning Shi, Carol M. Aherne, Allan M. Goldstein
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Mechanisms mediating adult enteric neurogenesis are largely unknown. Using inflammation-associated neurogenesis models and a transgenic approach, we aimed to understand the cell-source for new neurons in infectious and inflammatory colitis.
Externí odkaz:
https://doaj.org/article/98a0aa1a66ae46da8336099aaa713215
Autor:
Wei Zhang, Lefei Jiao, Ruixin Liu, Yu Zhang, Qiaorong Ji, Huan Zhang, Xiang Gao, Yan Ma, Hai Ning Shi
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203701 (2018)
This experiment was conducted to investigate the effect of exposure to high altitude and low oxygen on intestinal microbial communities using mice as an animal model. Fecal microbiota from mice housed in a control environment representing 2,200 meter
Externí odkaz:
https://doaj.org/article/ad22e1ddb41848f68a860d7812b1ff49
Autor:
Shao Rong Long, Zhong Quan Wang, Ruo Dan Liu, Li Na Liu, Ling Ge Li, Peng Jiang, Xi Zhang, Zi Fang Zhang, Hai Ning Shi, Jing Cui
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-10 (2014)
Abstract Background Nudix hydrolases (Nd) is a widespread superfamily, which is found in all classes of organism, hydrolyse a wide range of organic pyrophosphates and has a ‘housecleaning’ function. The previous study showed that Trichinella spir
Externí odkaz:
https://doaj.org/article/53bc0bf1326c4c03bdf902f5afadb769
Autor:
Yali Li, Meili Lv, Chienwen Su, Shaorong Long, Wei Zhang, Kara L. Conway, Weifen Li, Ramnik J. Xavier, Hai Ning Shi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a major cause of acute gastroenteritis in humans. During infection, reactive oxygen species (ROS), generated from NADPH oxidase (a multisubunit enzyme complex), are required for pathogen kil
Externí odkaz:
https://doaj.org/article/970a787f3d3d4567875dbe1d9ab7d249
Autor:
Hai Ning Shi, Allan Walker
Publikováno v:
Canadian Journal of Gastroenterology, Vol 18, Iss 8, Pp 493-500 (2004)
In humans, intestinal defences develop during gestation and, at full term, have the capacity to respond in an appropriate manner to infectious agents and foreign antigens. Before an active protective response can occur, however, the gut must first be
Externí odkaz:
https://doaj.org/article/73c7188879154fd99f9c496a0e6b999b
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2987 (2014)
Infections with intestinal helminth and bacterial pathogens, such as enteropathogenic Escherichia coli, continue to be a major global health threat for children. To determine whether and how an intestinal helminth parasite, Heligomosomoides polygyrus
Externí odkaz:
https://doaj.org/article/2026b5bcb58a469bab80b5028a32c213